An Overview of Literature Topics Related to Current Concepts, Methods, Tools, and Applications for Cumulative Risk Assessment (2007–2016)
Abstract
Cumulative risk assessments (CRAs) address combined risks from exposures to multiple chemical and nonchemical stressors and may focus on vulnerable communities or populations. Significant contributions have been made to the development of concepts, methods, and applications for CRA over the past decade. Work in both human health and ecological cumulative risk has advanced in two different contexts. The first context is the effects of chemical mixtures that share common modes of action, or that cause common adverse outcomes. In this context two primary models are used for predicting mixture effects, dose addition or response addition. The second context is evaluating the combined effects of chemical and nonchemical (e.g., radiation, biological, nutritional, economic, psychological, habitat alteration, land-use change, global climate change, and natural disasters) stressors. CRA can be adapted to address risk in many contexts, and this adaptability is reflected in the range in disciplinary perspectives in the published literature. This article presents the results of a literature search and discusses a range of selected work with the intention to give a broad overview of relevant topics and provide a starting point for researchers interested in CRA applications.
- Authors:
-
[3]
- Johns Hopkins Univ., Baltimore, MD (United States). Department of Health Policy and Management, Bloomberg School of Public Health
- Oak Ridge Inst. for Science and Education (ORISE), Washington, DC (United States). Office of the Science Advisor, U.S. Environmental Protection Agency
- US Environmental Protection Agency (EPA), Washington, DC (United States). Office of the Science Advisor
- Publication Date:
- Research Org.:
- Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE; USEPA
- OSTI Identifier:
- 1628340
- Grant/Contract Number:
- SC0014664
- Resource Type:
- Accepted Manuscript
- Journal Name:
- International Journal of Environmental Research and Public Health
- Additional Journal Information:
- Journal Volume: 14; Journal Issue: 4; Journal ID: ISSN 1660-4601
- Publisher:
- MDPI
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES; Environmental Sciences & Ecology; Public, Environmental & Occupational Health
Citation Formats
Fox, Mary, Brewer, L., and Martin, Lawrence. An Overview of Literature Topics Related to Current Concepts, Methods, Tools, and Applications for Cumulative Risk Assessment (2007–2016). United States: N. p., 2017.
Web. doi:10.3390/ijerph14040389.
Fox, Mary, Brewer, L., & Martin, Lawrence. An Overview of Literature Topics Related to Current Concepts, Methods, Tools, and Applications for Cumulative Risk Assessment (2007–2016). United States. https://doi.org/10.3390/ijerph14040389
Fox, Mary, Brewer, L., and Martin, Lawrence. Fri .
"An Overview of Literature Topics Related to Current Concepts, Methods, Tools, and Applications for Cumulative Risk Assessment (2007–2016)". United States. https://doi.org/10.3390/ijerph14040389. https://www.osti.gov/servlets/purl/1628340.
@article{osti_1628340,
title = {An Overview of Literature Topics Related to Current Concepts, Methods, Tools, and Applications for Cumulative Risk Assessment (2007–2016)},
author = {Fox, Mary and Brewer, L. and Martin, Lawrence},
abstractNote = {Cumulative risk assessments (CRAs) address combined risks from exposures to multiple chemical and nonchemical stressors and may focus on vulnerable communities or populations. Significant contributions have been made to the development of concepts, methods, and applications for CRA over the past decade. Work in both human health and ecological cumulative risk has advanced in two different contexts. The first context is the effects of chemical mixtures that share common modes of action, or that cause common adverse outcomes. In this context two primary models are used for predicting mixture effects, dose addition or response addition. The second context is evaluating the combined effects of chemical and nonchemical (e.g., radiation, biological, nutritional, economic, psychological, habitat alteration, land-use change, global climate change, and natural disasters) stressors. CRA can be adapted to address risk in many contexts, and this adaptability is reflected in the range in disciplinary perspectives in the published literature. This article presents the results of a literature search and discusses a range of selected work with the intention to give a broad overview of relevant topics and provide a starting point for researchers interested in CRA applications.},
doi = {10.3390/ijerph14040389},
journal = {International Journal of Environmental Research and Public Health},
number = 4,
volume = 14,
place = {United States},
year = {Fri Apr 07 00:00:00 EDT 2017},
month = {Fri Apr 07 00:00:00 EDT 2017}
}
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Novel methods for integrated risk assessment of cumulative stressors — Results from the NoMiracle project
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Genotoxicity induced by pesticide mixtures: in-vitro studies on human peripheral blood lymphocytes
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Adverse Outcome Pathway (AOP) Development I: Strategies and Principles
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Community health assessment using self-organizing maps and geographic information systems
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Works referencing / citing this record:
Biomonitoring and Subsequent Risk Assessment of Combined Exposure to Phthalates in Iranian Children and Adolescents
journal, October 2018
- Zare Jeddi, Maryam; Eshaghi Gorji, Mohamad; Rietjens, Ivonne
- International Journal of Environmental Research and Public Health, Vol. 15, Issue 11
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