Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers
- Authors:
-
[1];
- Pennsylvania State Univ., University Park, PA (United States)
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- Harvard Medical School, Boston, MA (United States)
- Publication Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE National Nuclear Security Administration (NNSA); National Science Foundation (NSF); National Institutes of Health (NIH)
- OSTI Identifier:
- 1627260
- Alternate Identifier(s):
- OSTI ID: 1663186
- Report Number(s):
- LA-UR-18-28993
Journal ID: ISSN 1553-7358; TRN: US2200431
- Grant/Contract Number:
- 89233218CNA000001; DMS-1714654; R01-AI028433; R01-OD011095; P01-AI131365; AI114448; UM1 AI068636
- Resource Type:
- Accepted Manuscript
- Journal Name:
- PLoS Computational Biology (Online)
- Additional Journal Information:
- Journal Name: PLoS Computational Biology (Online); Journal Volume: 15; Journal Issue: 7; Journal ID: ISSN 1553-7358
- Publisher:
- Public Library of Science
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES; Biochemistry & Molecular Biology; Mathematical & Computational Biology; Biological Science
Citation Formats
Conway, Jessica M., Perelson, Alan S., and Li, Jonathan Z. Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers. United States: N. p., 2019.
Web. doi:10.1371/journal.pcbi.1007229.
Conway, Jessica M., Perelson, Alan S., & Li, Jonathan Z. Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers. United States. https://doi.org/10.1371/journal.pcbi.1007229
Conway, Jessica M., Perelson, Alan S., and Li, Jonathan Z. Wed .
"Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers". United States. https://doi.org/10.1371/journal.pcbi.1007229. https://www.osti.gov/servlets/purl/1627260.
@article{osti_1627260,
title = {Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers},
author = {Conway, Jessica M. and Perelson, Alan S. and Li, Jonathan Z.},
abstractNote = {},
doi = {10.1371/journal.pcbi.1007229},
journal = {PLoS Computational Biology (Online)},
number = 7,
volume = 15,
place = {United States},
year = {Wed Jul 24 00:00:00 EDT 2019},
month = {Wed Jul 24 00:00:00 EDT 2019}
}
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Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs
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- Proceedings of the National Academy of Sciences, Vol. 96, Issue 26
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HIV Controllers: A Homogeneous Group of HIV-1--Infected Patients with Spontaneous Control of Viral Replication
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- Clinical Infectious Diseases, Vol. 41, Issue 7
Pharmacogenetics of Plasma Efavirenz Exposure after Treatment Discontinuation: An Adult AIDS Clinical Trials Group Study
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Evidence That Intermittent Structured Treatment Interruption, but Not Immunization with ALVAC‐HIV vCP1452, Promotes Host Control of HIV Replication: The Results of AIDS Clinical Trials Group 5068
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- Jacobson, Jeffrey M.; Pat Bucy, R.; Spritzler, John
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A Randomized, Partially Blinded Phase 2 Trial of Antiretroviral Therapy, HIV‐Specific Immunizations, and Interleukin‐2 Cycles to Promote Efficient Control of Viral Replication (ACTG A5024)
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Interruption of Antiretroviral Treatment in HIV‐Infected Patients with Preserved Immune Function Is Associated with a Low Rate of Clinical Progression: A Prospective Study by AIDS Clinical Trials Group 5170
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AIDS Clinical Trials Group 5197: A Placebo‐Controlled Trial of Immunization of HIV‐1–Infected Persons with a Replication‐Deficient Adenovirus Type 5 Vaccine Expressing the HIV‐1 Core Protein
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Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
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HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time
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Stochastic Analysis of Pre- and Postexposure Prophylaxis against HIV Infection
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- SIAM Journal on Applied Mathematics, Vol. 73, Issue 2
PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors
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- Blood, Vol. 109, Issue 11
Modeling the within-host dynamics of HIV infection
journal, September 2013
- Perelson, Alan S.; Ribeiro, Ruy M.
- BMC Biology, Vol. 11, Issue 1
What do we measure when we measure cell-associated HIV RNA
journal, January 2018
- Pasternak, Alexander O.; Berkhout, Ben
- Retrovirology, Vol. 15, Issue 1
Multistage models of carcinogenesis.
journal, November 1985
- Armitage, P.
- Environmental Health Perspectives, Vol. 63
A Stochastic Model of Latently Infected Cell Reactivation and Viral Blip Generation in Treated HIV Patients
journal, April 2011
- Conway, Jessica M.; Coombs, Daniel
- PLoS Computational Biology, Vol. 7, Issue 4
HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study
journal, November 2017
- Henrich, Timothy J.; Hatano, Hiroyu; Bacon, Oliver
- PLOS Medicine, Vol. 14, Issue 11
Safety and Immunogenicity of Therapeutic DNA Vaccination in Individuals Treated with Antiretroviral Therapy during Acute/Early HIV-1 Infection
journal, May 2010
- Rosenberg, Eric S.; Graham, Barney S.; Chan, Ellen S.
- PLoS ONE, Vol. 5, Issue 5
HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission
journal, July 2015
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Intracellular Pharmacokinetics of Antiretroviral Drugs in HIV-Infected Patients, and their Correlation with Drug Action
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