Indirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic Partnership
Abstract
This study elucidates how a cyanobacterial primary producer acclimates to heterotrophic partnership by modulating the expression levels of key metabolic genes. Heterotrophic bacteria can indirectly regulate the physiology of the photoautotrophic primary producers, resulting in physiological changes identified here, such as increased intracellular ROS. Some of the interactions inferred from this model system represent putative principles of metabolic coupling in phototrophic-heterotrophic partnerships. The mechanisms by which microbes interact in communities remain poorly understood. Here, we interrogated specific interactions between photoautotrophic and heterotrophic members of a model consortium to infer mechanisms that mediate metabolic coupling and acclimation to partnership. This binary consortium was composed of a cyanobacterium,Thermosynechococcus elongatusBP-1, which supported growth of an obligate aerobic heterotroph,Meiothermus ruberstrain A, by providing organic carbon, O2, and reduced nitrogen. Species-resolved transcriptomic analyses were used in combination with growth and photosynthesis kinetics to infer interactions and the environmental context under which they occur. We found that the efficiency of biomass production and resistance to stress induced by high levels of dissolved O2 increased, beyond axenic performance, as a result of heterotrophic partnership. Coordinated transcriptional responses transcending both species were observed and used to infer specific interactions resulting from the synthesis and exchange of resources. Themore »
- Authors:
-
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Washington State Univ., Pullman, WA (United States)
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
- Pennsylvania State Univ., University Park, PA (United States)
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab.
- Pennsylvania State Univ., University Park, PA (United States); Montana State Univ., Bozeman, MT (United States)
- Publication Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Biological and Environmental Research (BER)
- OSTI Identifier:
- 1626177
- Grant/Contract Number:
- AC06-76RL01830; 49356
- Resource Type:
- Accepted Manuscript
- Journal Name:
- mSystems
- Additional Journal Information:
- Journal Volume: 2; Journal Issue: 2; Journal ID: ISSN 2379-5077
- Publisher:
- American Society for Microbiology
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; Microbiology; consortia; cyanobacteria; heterotroph; microbial interactions; transcriptome
Citation Formats
Bernstein, Hans C., McClure, Ryan S., Thiel, Vera, Sadler, Natalie C., Kim, Young-Mo, Chrisler, William B., Hill, Eric A., Bryant, Donald A., Romine, Margaret F., Jansson, Janet K., Fredrickson, Jim K., and Beliaev, Alexander S. Indirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic Partnership. United States: N. p., 2017.
Web. doi:10.1128/msystems.00181-16.
Bernstein, Hans C., McClure, Ryan S., Thiel, Vera, Sadler, Natalie C., Kim, Young-Mo, Chrisler, William B., Hill, Eric A., Bryant, Donald A., Romine, Margaret F., Jansson, Janet K., Fredrickson, Jim K., & Beliaev, Alexander S. Indirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic Partnership. United States. https://doi.org/10.1128/msystems.00181-16
Bernstein, Hans C., McClure, Ryan S., Thiel, Vera, Sadler, Natalie C., Kim, Young-Mo, Chrisler, William B., Hill, Eric A., Bryant, Donald A., Romine, Margaret F., Jansson, Janet K., Fredrickson, Jim K., and Beliaev, Alexander S. Tue .
"Indirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic Partnership". United States. https://doi.org/10.1128/msystems.00181-16. https://www.osti.gov/servlets/purl/1626177.
@article{osti_1626177,
title = {Indirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic Partnership},
author = {Bernstein, Hans C. and McClure, Ryan S. and Thiel, Vera and Sadler, Natalie C. and Kim, Young-Mo and Chrisler, William B. and Hill, Eric A. and Bryant, Donald A. and Romine, Margaret F. and Jansson, Janet K. and Fredrickson, Jim K. and Beliaev, Alexander S.},
abstractNote = {This study elucidates how a cyanobacterial primary producer acclimates to heterotrophic partnership by modulating the expression levels of key metabolic genes. Heterotrophic bacteria can indirectly regulate the physiology of the photoautotrophic primary producers, resulting in physiological changes identified here, such as increased intracellular ROS. Some of the interactions inferred from this model system represent putative principles of metabolic coupling in phototrophic-heterotrophic partnerships. The mechanisms by which microbes interact in communities remain poorly understood. Here, we interrogated specific interactions between photoautotrophic and heterotrophic members of a model consortium to infer mechanisms that mediate metabolic coupling and acclimation to partnership. This binary consortium was composed of a cyanobacterium,Thermosynechococcus elongatusBP-1, which supported growth of an obligate aerobic heterotroph,Meiothermus ruberstrain A, by providing organic carbon, O2, and reduced nitrogen. Species-resolved transcriptomic analyses were used in combination with growth and photosynthesis kinetics to infer interactions and the environmental context under which they occur. We found that the efficiency of biomass production and resistance to stress induced by high levels of dissolved O2 increased, beyond axenic performance, as a result of heterotrophic partnership. Coordinated transcriptional responses transcending both species were observed and used to infer specific interactions resulting from the synthesis and exchange of resources. The cyanobacterium responded to heterotrophic partnership by altering expression of core genes involved with photosynthesis, carbon uptake/fixation, vitamin synthesis, and scavenging of reactive oxygen species (ROS). IMPORTANCEThis study elucidates how a cyanobacterial primary producer acclimates to heterotrophic partnership by modulating the expression levels of key metabolic genes. Heterotrophic bacteria can indirectly regulate the physiology of the photoautotrophic primary producers, resulting in physiological changes identified here, such as increased intracellular ROS. Some of the interactions inferred from this model system represent putative principles of metabolic coupling in phototrophic-heterotrophic partnerships.},
doi = {10.1128/msystems.00181-16},
journal = {mSystems},
number = 2,
volume = 2,
place = {United States},
year = {Tue Mar 07 00:00:00 EST 2017},
month = {Tue Mar 07 00:00:00 EST 2017}
}
Web of Science
Figures / Tables:
Works referenced in this record:
Microenvironmental Control of Photosynthesis and Photosynthesis-Coupled Respiration in an Epilithic Cyanobacterial Biofilm1
journal, October 1996
- Kuhl, Michael; Glud, Ronnie Nohr; Ploug, Helle
- Journal of Phycology, Vol. 32, Issue 5
Complete Genome Structure of the Thermophilic Cyanobacterium Thermosynechococcus elongatus BP-1
journal, January 2002
- Nakamura, Y.
- DNA Research, Vol. 9, Issue 4, p. 123-130
Unlocking the Constraints of Cyanobacterial Productivity: Acclimations Enabling Ultrafast Growth
journal, July 2016
- Bernstein, Hans C.; McClure, Ryan S.; Hill, Eric A.
- mBio, Vol. 7, Issue 4
Microbial Consortia Engineering for Cellular Factories: in Vitro to in Silico Systems
journal, October 2012
- Bernstein, Hans C.; Carlson, Ross P.
- Computational and Structural Biotechnology Journal, Vol. 3, Issue 4
Peroxiredoxins in Plants and Cyanobacteria
journal, August 2011
- Dietz, Karl-Josef
- Antioxidants & Redox Signaling, Vol. 15, Issue 4
The Dark Side of the Mushroom Spring Microbial Mat: Life in the Shadow of Chlorophototrophs. I. Microbial Diversity Based on 16S rRNA Gene Amplicons and Metagenomic Sequencing
journal, June 2016
- Thiel, Vera; Wood, Jason M.; Olsen, Millie T.
- Frontiers in Microbiology, Vol. 7
Widespread Production of Extracellular Superoxide by Heterotrophic Bacteria
journal, May 2013
- Diaz, J. M.; Hansel, C. M.; Voelker, B. M.
- Science, Vol. 340, Issue 6137
Microbial Community Metabolic Modeling: A Community Data-Driven Network Reconstruction: COMMUNITY DATA-DRIVEN METABOLIC NETWORK MODELING
journal, June 2016
- Henry, Christopher S.; Bernstein, Hans C.; Weisenhorn, Pamela
- Journal of Cellular Physiology, Vol. 231, Issue 11
Trade-offs between microbiome diversity and productivity in a stratified microbial mat
journal, November 2016
- Bernstein, Hans C.; Brislawn, Colin; Renslow, Ryan S.
- The ISME Journal, Vol. 11, Issue 2
Functional and Structural Characterization of the 2/2 Hemoglobin from Synechococcus sp. PCC 7002,
journal, August 2010
- Scott, Nancy L.; Xu, Yu; Shen, Gaozhong
- Biochemistry, Vol. 49, Issue 33
Multi-Omic Dynamics Associate Oxygenic Photosynthesis with Nitrogenase-Mediated H2 Production in Cyanothece sp. ATCC 51142
journal, November 2015
- Bernstein, Hans C.; Charania, Moiz A.; McClure, Ryan S.
- Scientific Reports, Vol. 5, Issue 1
Optical properties of microbial mats: Light measurements with fiber-optic microprobes
book, January 1994
- Kühl, Michael; Lassen, Carsten; Jørgensen, Bo Barker
- Microbial Mats
HTSeq--a Python framework to work with high-throughput sequencing data
journal, September 2014
- Anders, S.; Pyl, P. T.; Huber, W.
- Bioinformatics, Vol. 31, Issue 2
Photo-oxidative Stress in a Xanthophyll-deficient Mutant of Chlamydomonas
journal, December 2003
- Baroli, Irene; Gutman, Benjamin L.; Ledford, Heidi K.
- Journal of Biological Chemistry, Vol. 279, Issue 8
Synthetic Escherichia coli consortia engineered for syntrophy demonstrate enhanced biomass productivity
journal, January 2012
- Bernstein, Hans C.; Paulson, Steven D.; Carlson, Ross P.
- Journal of Biotechnology, Vol. 157, Issue 1
Torn apart and reunited: impact of a heterotroph on the transcriptome of Prochlorococcus
journal, June 2016
- Biller, Steven J.; Coe, Allison; Chisholm, Sallie W.
- The ISME Journal, Vol. 10, Issue 12
The cost of photoinhibition
journal, March 2011
- Raven, John A.
- Physiologia Plantarum, Vol. 142, Issue 1
Isolation, subunit composition and interaction of the NDH-1 complexes from Thermosynechococcus elongatus BP-1
journal, August 2005
- Zhang, Pengpeng; Battchikova, Natalia; Paakkarinen, Virpi
- Biochemical Journal, Vol. 390, Issue 2
A cyanophycin synthetase from Thermosynechococcus elongatus BP-1 catalyzes primer-independent cyanophycin synthesis
journal, November 2008
- Arai, Toshinobu; Kino, Kuniki
- Applied Microbiology and Biotechnology, Vol. 81, Issue 1
The molecular dimension of microbial species: 2. Synechococcus strains representative of putative ecotypes inhabiting different depths in the Mushroom Spring microbial mat exhibit different adaptive and acclimative responses to light
journal, June 2015
- Nowack, Shane; Olsen, Millie T.; Schaible, George A.
- Frontiers in Microbiology, Vol. 6
Direct measurement and characterization of active photosynthesis zones inside wastewater remediating and biofuel producing microalgal biofilms
journal, March 2014
- Bernstein, Hans C.; Kesaano, Maureen; Moll, Karen
- Bioresource Technology, Vol. 156
Effects of Biodiversity on Ecosystem Functioning: a Consensus of Current Knowledge
journal, February 2005
- Hooper, D. U.; Chapin, F. S.; Ewel, J. J.
- Ecological Monographs, Vol. 75, Issue 1
Temporal discontinuity of nutrient limitation in plankton communities
journal, May 2010
- Davies, John-Mark; Nowlin, Weston H.; Matthews, Blake
- Aquatic Sciences, Vol. 72, Issue 4
Inference of interactions in cyanobacterial–heterotrophic co-cultures via transcriptome sequencing
journal, April 2014
- Beliaev, Alexander S.; Romine, Margie F.; Serres, Margrethe
- The ISME Journal, Vol. 8, Issue 11
Dependence of the Cyanobacterium Prochlorococcus on Hydrogen Peroxide Scavenging Microbes for Growth at the Ocean's Surface
journal, February 2011
- Morris, J. Jeffrey; Johnson, Zackary I.; Szul, Martin J.
- PLoS ONE, Vol. 6, Issue 2
Whole-genome microarray analyses of Synechococcus - Vibrio interactions
journal, October 2009
- Tai, Vera; Paulsen, Ian T.; Phillippy, Katherine
- Environmental Microbiology, Vol. 11, Issue 10
Cyanobacterial ecotypes in the microbial mat community of Mushroom Spring (Yellowstone National Park, Wyoming) as species-like units linking microbial community composition, structure and function
journal, October 2006
- Ward, David M.; Bateson, Mary M.; Ferris, Michael J.
- Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 361, Issue 1475
Parameters of photosynthesis: definitions, theory and interpretation of results
journal, January 1997
- Sakshaug, E.; Bricaud, A.; Dandonneau, Y.
- Journal of Plankton Research, Vol. 19, Issue 11
Thermus ruber sp. nov., nom. rev.
journal, October 1984
- Loginova, L. G.; Egorova, L. A.; Golovacheva, R. S.
- International Journal of Systematic Bacteriology, Vol. 34, Issue 4
Transcriptional response of Prochlorococcus to co-culture with a marine Alteromonas: differences between strains and the involvement of putative infochemicals
journal, April 2016
- Aharonovich, Dikla; Sher, Daniel
- The ISME Journal, Vol. 10, Issue 12
Effect of mono- and dichromatic light quality on growth rates and photosynthetic performance of Synechococcus sp. PCC 7002
journal, September 2014
- Bernstein, Hans C.; Konopka, Allan; Melnicki, Matthew R.
- Frontiers in Microbiology, Vol. 5
Applications of cyanobacteria in biotechnology
journal, January 2009
- Abed, R. M. M.; Dobretsov, S.; Sudesh, K.
- Journal of Applied Microbiology, Vol. 106, Issue 1
Photosynthetic activities of a thermophilic blue-green alga
journal, September 1978
- Yamaoka, Takashi; Satoh, Kazuhiko; Katoh, Sakae
- Plant and Cell Physiology, Vol. 19, Issue 6
Photosynthetic accumulation of carbon storage compounds under CO2 enrichment by the thermophilic cyanobacterium Thermosynechococcus elongatus
journal, March 2012
- Eberly, Jed O.; Ely, Roger L.
- Journal of Industrial Microbiology & Biotechnology, Vol. 39, Issue 6
Metabolic Sources of Hydrogen Peroxide in Aerobically Growing Escherichia coli
journal, June 1995
- González-Flecha, Beatriz; Demple, Bruce
- Journal of Biological Chemistry, Vol. 270, Issue 23
Biogeochemical Controls and Feedbacks on Ocean Primary Production
journal, July 1998
- Falkowski, P. G.
- Science, Vol. 281, Issue 5374
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
journal, December 2014
- Love, Michael I.; Huber, Wolfgang; Anders, Simon
- Genome Biology, Vol. 15, Issue 12
Roles of xanthophyll carotenoids in protection against photoinhibition and oxidative stress in the cyanobacterium Synechococcus sp. strain PCC 7002
journal, December 2010
- Zhu, Yuehui; Graham, Joel E.; Ludwig, Marcus
- Archives of Biochemistry and Biophysics, Vol. 504, Issue 1
The Elip Family of Stress Proteins in the Thylakoid Membranes of Pro- and Eukaryota
book, January 2001
- Adamska, Iwona
- Regulation of Photosynthesis
Feedback-controlled LED photobioreactor for photophysiological studies of cyanobacteria
journal, April 2013
- Melnicki, Matthew R.; Pinchuk, Grigoriy E.; Hill, Eric A.
- Bioresource Technology, Vol. 134
The Elip Family of Stress Proteins in the Thylakoid Membranes of Pro- and Eukaryota
book, January 2001
- Adamska, Iwona
- Regulation of Photosynthesis
Temporal discontinuity of nutrient limitation in plankton communities
journal, May 2010
- Davies, John-Mark; Nowlin, Weston H.; Matthews, Blake
- Aquatic Sciences, Vol. 72, Issue 4
A cyanophycin synthetase from Thermosynechococcus elongatus BP-1 catalyzes primer-independent cyanophycin synthesis
journal, November 2008
- Arai, Toshinobu; Kino, Kuniki
- Applied Microbiology and Biotechnology, Vol. 81, Issue 1
Photosynthetic accumulation of carbon storage compounds under CO2 enrichment by the thermophilic cyanobacterium Thermosynechococcus elongatus
journal, March 2012
- Eberly, Jed O.; Ely, Roger L.
- Journal of Industrial Microbiology & Biotechnology, Vol. 39, Issue 6
Roles of xanthophyll carotenoids in protection against photoinhibition and oxidative stress in the cyanobacterium Synechococcus sp. strain PCC 7002
journal, December 2010
- Zhu, Yuehui; Graham, Joel E.; Ludwig, Marcus
- Archives of Biochemistry and Biophysics, Vol. 504, Issue 1
Feedback-controlled LED photobioreactor for photophysiological studies of cyanobacteria
journal, April 2013
- Melnicki, Matthew R.; Pinchuk, Grigoriy E.; Hill, Eric A.
- Bioresource Technology, Vol. 134
Direct measurement and characterization of active photosynthesis zones inside wastewater remediating and biofuel producing microalgal biofilms
journal, March 2014
- Bernstein, Hans C.; Kesaano, Maureen; Moll, Karen
- Bioresource Technology, Vol. 156
Synthetic Escherichia coli consortia engineered for syntrophy demonstrate enhanced biomass productivity
journal, January 2012
- Bernstein, Hans C.; Paulson, Steven D.; Carlson, Ross P.
- Journal of Biotechnology, Vol. 157, Issue 1
Functional and Structural Characterization of the 2/2 Hemoglobin from Synechococcus sp. PCC 7002,
journal, August 2010
- Scott, Nancy L.; Xu, Yu; Shen, Gaozhong
- Biochemistry, Vol. 49, Issue 33
Inference of interactions in cyanobacterial–heterotrophic co-cultures via transcriptome sequencing
journal, April 2014
- Beliaev, Alexander S.; Romine, Margie F.; Serres, Margrethe
- The ISME Journal, Vol. 8, Issue 11
Transcriptional response of Prochlorococcus to co-culture with a marine Alteromonas: differences between strains and the involvement of putative infochemicals
journal, April 2016
- Aharonovich, Dikla; Sher, Daniel
- The ISME Journal, Vol. 10, Issue 12
Multi-Omic Dynamics Associate Oxygenic Photosynthesis with Nitrogenase-Mediated H2 Production in Cyanothece sp. ATCC 51142
journal, November 2015
- Bernstein, Hans C.; Charania, Moiz A.; McClure, Ryan S.
- Scientific Reports, Vol. 5, Issue 1
Metabolic Sources of Hydrogen Peroxide in Aerobically Growing Escherichia coli
journal, June 1995
- González-Flecha, Beatriz; Demple, Bruce
- Journal of Biological Chemistry, Vol. 270, Issue 23
Functional Characterization and Quantification of the Alternative PsbA Copies in Thermosynechococcus elongatus and Their Role in Photoprotection
journal, July 2010
- Sander, Julia; Nowaczyk, Marc; Buchta, Joachim
- Journal of Biological Chemistry, Vol. 285, Issue 39
Peroxiredoxins in Plants and Cyanobacteria
journal, August 2011
- Dietz, Karl-Josef
- Antioxidants & Redox Signaling, Vol. 15, Issue 4
Complete Genome Structure of the Thermophilic Cyanobacterium Thermosynechococcus elongatus BP-1
journal, January 2002
- Nakamura, Y.
- DNA Research, Vol. 9, Issue 4, p. 123-130
Parameters of photosynthesis: definitions, theory and interpretation of results
journal, January 1997
- Sakshaug, E.; Bricaud, A.; Dandonneau, Y.
- Journal of Plankton Research, Vol. 19, Issue 11
Cyanobacterial ecotypes in the microbial mat community of Mushroom Spring (Yellowstone National Park, Wyoming) as species-like units linking microbial community composition, structure and function
journal, October 2006
- Ward, David M.; Bateson, Mary M.; Ferris, Michael J.
- Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 361, Issue 1475
Microenvironmental Control of Photosynthesis and Photosynthesis-Coupled Respiration in an Epilithic Cyanobacterial Biofilm1
journal, October 1996
- Kuhl, Michael; Glud, Ronnie Nohr; Ploug, Helle
- Journal of Phycology, Vol. 32, Issue 5
Applications of cyanobacteria in biotechnology
journal, January 2009
- Abed, R. M. M.; Dobretsov, S.; Sudesh, K.
- Journal of Applied Microbiology, Vol. 106, Issue 1
The cost of photoinhibition
journal, March 2011
- Raven, John A.
- Physiologia Plantarum, Vol. 142, Issue 1
Widespread Production of Extracellular Superoxide by Heterotrophic Bacteria
journal, May 2013
- Diaz, J. M.; Hansel, C. M.; Voelker, B. M.
- Science, Vol. 340, Issue 6137
Biogeochemical Controls and Feedbacks on Ocean Primary Production
journal, July 1998
- Falkowski, P. G.
- Science, Vol. 281, Issue 5374
Effect of Temperature and Light on Growth of and Photosynthesis by Synechococcus Isolates Typical of Those Predominating in the Octopus Spring Microbial Mat Community of Yellowstone National Park
journal, January 2006
- Allewalt, J. P.; Bateson, M. M.; Revsbech, N. P.
- Applied and Environmental Microbiology, Vol. 72, Issue 1
Draft Genome Sequence of the Deinococcus-Thermus Bacterium Meiothermus ruber Strain A
journal, March 2015
- Thiel, Vera; Tomsho, Lynn P.; Burhans, Richard
- Genome Announcements, Vol. 3, Issue 2
Circadian Rhythms in the Thermophilic Cyanobacterium Thermosynechococcus elongatus: Compensation of Period Length over a Wide Temperature Range
journal, August 2004
- Onai, Kiyoshi; Morishita, Megumi; Itoh, Shino
- Journal of Bacteriology, Vol. 186, Issue 15
Dependence of the Cyanobacterium Prochlorococcus on Hydrogen Peroxide Scavenging Microbes for Growth at the Ocean's Surface
journal, February 2011
- Morris, J. Jeffrey; Johnson, Zackary I.; Szul, Martin J.
- PLoS ONE, Vol. 6, Issue 2
Effects of Biodiversity on Ecosystem Functioning: a Consensus of Current Knowledge
journal, February 2005
- Hooper, D. U.; Chapin, F. S.; Ewel, J. J.
- Ecological Monographs, Vol. 75, Issue 1
Effect of mono- and dichromatic light quality on growth rates and photosynthetic performance of Synechococcus sp. PCC 7002
journal, September 2014
- Bernstein, Hans C.; Konopka, Allan; Melnicki, Matthew R.
- Frontiers in Microbiology, Vol. 5
The molecular dimension of microbial species: 2. Synechococcus strains representative of putative ecotypes inhabiting different depths in the Mushroom Spring microbial mat exhibit different adaptive and acclimative responses to light
journal, June 2015
- Nowack, Shane; Olsen, Millie T.; Schaible, George A.
- Frontiers in Microbiology, Vol. 6
Microbial Consortia Engineering for Cellular Factories: in Vitro to in Silico Systems
journal, October 2012
- Bernstein, Hans C.; Carlson, Ross P.
- Computational and Structural Biotechnology Journal, Vol. 3, Issue 4
Works referencing / citing this record:
Species-specific transcriptomic network inference of interspecies interactions
journal, May 2018
- McClure, Ryan S.; Overall, Christopher C.; Hill, Eric A.
- The ISME Journal, Vol. 12, Issue 8
Phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture
journal, January 2018
- Khan, Nymul; Maezato, Yukari; McClure, Ryan S.
- Scientific Reports, Vol. 8, Issue 1
Heterotroph Interactions Alter Prochlorococcus Transcriptome Dynamics during Extended Periods of Darkness
journal, May 2018
- Biller, Steven J.; Coe, Allison; Roggensack, Sara E.
- mSystems, Vol. 3, Issue 3
Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2
journal, May 2020
- Zhang, Li; Chen, Lei; Diao, Jinjin
- Biotechnology for Biofuels, Vol. 13, Issue 1
Effect of light wavelength on hot spring microbial mat biodiversity
journal, January 2018
- Nishida, Akifumi; Thiel, Vera; Nakagawa, Mayuko
- PLOS ONE, Vol. 13, Issue 1
The Ecology of Subaerial Biofilms in Dry and Inhospitable Terrestrial Environments
journal, September 2019
- Villa, Federica; Cappitelli, Francesca
- Microorganisms, Vol. 7, Issue 10
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journal, January 2018
- Khan, Nymul; Maezato, Yukari; McClure, Ryan S.
- Scientific Reports, Vol. 8, Issue 1
Reconciling Ecological and Engineering Design Principles for Building Microbiomes
journal, May 2019
- Bernstein, Hans C.
- mSystems, Vol. 4, Issue 3
Effect of light wavelength on hot spring microbial mat biodiversity
journal, January 2018
- Nishida, Akifumi; Thiel, Vera; Nakagawa, Mayuko
- PLOS ONE, Vol. 13, Issue 1
Model Microbial Consortia as Tools for Understanding Complex Microbial Communities
journal, October 2018
- Haruta, Shin; Yamamoto, Kyosuke
- Current Genomics, Vol. 19, Issue 8
Figures / Tables found in this record: