Enhanced 1H-X D-HMQC performance through improved 1H homonuclear decoupling

Perras, Frédéric A.; Goh, Tian Wei; Wang, Lin -Lin; Huang, Wenyu; Pruski, Marek

doi:10.1016/j.ssnmr.2019.01.001

Title: Enhanced ¹H-X D-HMQC performance through improved ¹H homonuclear decoupling

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Abstract

The sensitivity of solid-state NMR experiments that utilize ¹H zero-quantum heteronuclear dipolar recoupling, such as D-HMQC, is compromised by poor homonuclear decoupling. This leads to a rapid decay of recoupled magnetization and an inefficient recoupling of long-range dipolar interactions, especially for nuclides with low gyromagnetic ratios. We investigated the use, in symmetry-based ¹H heteronuclear recoupling sequences, of a basic R element that was principally designed for efficient homonuclear decoupling. By shortening the time required to suppress the effects of homonuclear dipolar interactions to the duration of a single inversion pulse, spin diffusion was effectively quenched and long-lived recoupled coherence lifetimes could be obtained. Furthermore we show, both theoretically and experimentally, that these modified sequences can yield considerable sensitivity improvements over the current state-of-the-art methods and applied them to the indirect detection of 89Y in a metal-organic framework.

Authors:

Perras, Frédéric A. ^[1];

^[2]; Wang, Lin -Lin ^[1];

^[2]; Pruski, Marek ^[2]

Ames Lab., Ames, IA (United States)
Ames Lab. and Iowa State Univ., Ames, IA (United States)

Publication Date:: Thu Jan 10 00:00:00 EST 2019

Research Org.:: Ames Lab., Ames, IA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1494939

Alternate Identifier(s):: OSTI ID: 1547877

Report Number(s):: IS-J-9865
Journal ID: ISSN 0926-2040

Grant/Contract Number:: AC02-07CH11358

Resource Type:: Accepted Manuscript

Journal Name:: Solid State Nuclear Magnetic Resonance

Additional Journal Information:: Journal Volume: 98; Journal Issue: C; Journal ID: ISSN 0926-2040

Publisher:: Elsevier

Country of Publication:: United States

Language:: English

Subject:: 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; Heteronuclear correlation; Homonuclear decoupling; Solid-state NMR; Symmetry-based recoupling

Citation Formats


                    Perras, Frédéric A., Goh, Tian Wei, Wang, Lin -Lin, Huang, Wenyu, and Pruski, Marek. Enhanced 1H-X D-HMQC performance through improved 1H homonuclear decoupling.  United States: N. p., 2019. 
Web.  doi:10.1016/j.ssnmr.2019.01.001.

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                    Perras, Frédéric A., Goh, Tian Wei, Wang, Lin -Lin, Huang, Wenyu, & Pruski, Marek. Enhanced 1H-X D-HMQC performance through improved 1H homonuclear decoupling.  United States.  https://doi.org/10.1016/j.ssnmr.2019.01.001

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                    Perras, Frédéric A., Goh, Tian Wei, Wang, Lin -Lin, Huang, Wenyu, and Pruski, Marek. Thu .  
"Enhanced 1H-X D-HMQC performance through improved 1H homonuclear decoupling".  United States.  https://doi.org/10.1016/j.ssnmr.2019.01.001.  https://www.osti.gov/servlets/purl/1494939.

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@article{osti_1494939,

  title        = {Enhanced 1H-X D-HMQC performance through improved 1H homonuclear decoupling},

  author       = {Perras, Frédéric A. and Goh, Tian Wei and Wang, Lin -Lin and Huang, Wenyu and Pruski, Marek},

  abstractNote = {The sensitivity of solid-state NMR experiments that utilize 1H zero-quantum heteronuclear dipolar recoupling, such as D-HMQC, is compromised by poor homonuclear decoupling. This leads to a rapid decay of recoupled magnetization and an inefficient recoupling of long-range dipolar interactions, especially for nuclides with low gyromagnetic ratios. We investigated the use, in symmetry-based 1H heteronuclear recoupling sequences, of a basic R element that was principally designed for efficient homonuclear decoupling. By shortening the time required to suppress the effects of homonuclear dipolar interactions to the duration of a single inversion pulse, spin diffusion was effectively quenched and long-lived recoupled coherence lifetimes could be obtained. Furthermore we show, both theoretically and experimentally, that these modified sequences can yield considerable sensitivity improvements over the current state-of-the-art methods and applied them to the indirect detection of 89Y in a metal-organic framework.},

  doi          = {10.1016/j.ssnmr.2019.01.001},

  journal      = {Solid State Nuclear Magnetic Resonance},

  number       = C,

  volume       = 98,

  place        = {United States},

  year         = {Thu Jan 10 00:00:00 EST 2019},

  month        = {Thu Jan 10 00:00:00 EST 2019}

}

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Title: Enhanced 1H-X D-HMQC performance through improved 1H homonuclear decoupling

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Title: Enhanced ¹H-X D-HMQC performance through improved ¹H homonuclear decoupling