Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]
Abstract
Here, we disclose a novel, heterogeneous catalytic approach for selective coupling of C1 of N-aryltetrahydroisoquinolines with C3 of indoles in the presence of mesoporous manganese oxides. Our work involves a detailed mechanistic investigation of the reaction on the catalyst surface, backed by DFT computational studies, to understand the superior catalytic activity of manganese oxides.
- Authors:
-
- Univ. of Connecticut, Storrs, CT (United States)
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Publication Date:
- Research Org.:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1456820
- Grant/Contract Number:
- AC05-00OR22725
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Green Chemistry
- Additional Journal Information:
- Journal Volume: 19; Journal Issue: 22; Journal ID: ISSN 1463-9262
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Dutta, B., Sharma, Vinit K., Sassu, N., Dang, Y., Weerakkody, C., Macharia, J., Miao, R., Howell, A. R., and Suib, Steven L. Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]. United States: N. p., 2017.
Web. doi:10.1039/C7GC01919J.
Dutta, B., Sharma, Vinit K., Sassu, N., Dang, Y., Weerakkody, C., Macharia, J., Miao, R., Howell, A. R., & Suib, Steven L. Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]. United States. https://doi.org/10.1039/C7GC01919J
Dutta, B., Sharma, Vinit K., Sassu, N., Dang, Y., Weerakkody, C., Macharia, J., Miao, R., Howell, A. R., and Suib, Steven L. Wed .
"Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]". United States. https://doi.org/10.1039/C7GC01919J. https://www.osti.gov/servlets/purl/1456820.
@article{osti_1456820,
title = {Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]},
author = {Dutta, B. and Sharma, Vinit K. and Sassu, N. and Dang, Y. and Weerakkody, C. and Macharia, J. and Miao, R. and Howell, A. R. and Suib, Steven L.},
abstractNote = {Here, we disclose a novel, heterogeneous catalytic approach for selective coupling of C1 of N-aryltetrahydroisoquinolines with C3 of indoles in the presence of mesoporous manganese oxides. Our work involves a detailed mechanistic investigation of the reaction on the catalyst surface, backed by DFT computational studies, to understand the superior catalytic activity of manganese oxides.},
doi = {10.1039/C7GC01919J},
journal = {Green Chemistry},
number = 22,
volume = 19,
place = {United States},
year = {Wed Sep 27 00:00:00 EDT 2017},
month = {Wed Sep 27 00:00:00 EDT 2017}
}
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