An age-specific biokinetic model for iodine
Abstract
This study reviews age-specific biokinetic data for iodine in humans and extends to pre-adult ages the baseline parameter values of the author’s previously published model for systemic iodine in adult humans. Compared with the ICRP’s current age-specific model for iodine introduced in Publication 56 (1989), the present model provides a more detailed description of the behavior of iodine in the human body; predicts greater cumulative (integrated) activity in the thyroid for short-lived isotopes of iodine; predicts similar cumulative activity in the thyroid for isotopes with half-time greater than a few hours; and, for most iodine isotopes, predicts much greater cumulative activity in salivary glands, stomach wall, liver, and kidneys.
- Publication Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1409264
- Grant/Contract Number:
- AC05-00OR22725
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Journal of Radiological Protection
- Additional Journal Information:
- Journal Volume: 37; Journal Issue: 4; Journal ID: ISSN 0952-4746
- Publisher:
- IOP Publishing
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 61 RADIATION PROTECTION AND DOSIMETRY; iodine; biokinetics; model; age-specific
Citation Formats
Leggett, Richard Wayne. An age-specific biokinetic model for iodine. United States: N. p., 2017.
Web. doi:10.1088/1361-6498/aa8d30.
Leggett, Richard Wayne. An age-specific biokinetic model for iodine. United States. https://doi.org/10.1088/1361-6498/aa8d30
Leggett, Richard Wayne. Thu .
"An age-specific biokinetic model for iodine". United States. https://doi.org/10.1088/1361-6498/aa8d30. https://www.osti.gov/servlets/purl/1409264.
@article{osti_1409264,
title = {An age-specific biokinetic model for iodine},
author = {Leggett, Richard Wayne},
abstractNote = {This study reviews age-specific biokinetic data for iodine in humans and extends to pre-adult ages the baseline parameter values of the author’s previously published model for systemic iodine in adult humans. Compared with the ICRP’s current age-specific model for iodine introduced in Publication 56 (1989), the present model provides a more detailed description of the behavior of iodine in the human body; predicts greater cumulative (integrated) activity in the thyroid for short-lived isotopes of iodine; predicts similar cumulative activity in the thyroid for isotopes with half-time greater than a few hours; and, for most iodine isotopes, predicts much greater cumulative activity in salivary glands, stomach wall, liver, and kidneys.},
doi = {10.1088/1361-6498/aa8d30},
journal = {Journal of Radiological Protection},
number = 4,
volume = 37,
place = {United States},
year = {Thu Oct 26 00:00:00 EDT 2017},
month = {Thu Oct 26 00:00:00 EDT 2017}
}
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Works referencing / citing this record:
Adaptive biokinetic modelling of iodine-131 in thyroid cancer treatments: implications on individualised internal dosimetry
journal, November 2018
- Guiu-Souto, Jacobo; Neira-Castro, Sara; Sánchez-García, Manuel
- Journal of Radiological Protection, Vol. 38, Issue 4
Use of Iodine-131 to Tellurium-132 Ratios for Assessing the Relationships between Human Inhaled Radioactivity and Environmental Monitoring after the Accident in Fukushima
journal, March 2018
- Uchiyama, Koji; Miyashita, Masami; Tanishima, Yoshinobu
- International Journal of Environmental Research and Public Health, Vol. 15, Issue 3
Repeated KI Prophylaxis in Case of Prolonged Exposure to Iodine Radioisotopes: Pharmacokinetic Studies in Adult Rats
journal, October 2018
- Phan, Guillaume; Chioukh, Rym; Suhard, David
- Pharmaceutical Research, Vol. 35, Issue 12
Use of Iodine-131 to Tellurium-132 Ratios for Assessing the Relationships between Human Inhaled Radioactivity and Environmental Monitoring after the Accident in Fukushima
journal, March 2018
- Uchiyama, Koji; Miyashita, Masami; Tanishima, Yoshinobu
- International Journal of Environmental Research and Public Health, Vol. 15, Issue 3