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Title: Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice

Abstract

In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. In this paper, perylene-3,4,9,10-tetracarboxylic diiimide-based near-infrared-absorptive organic nanoparticles are reported as an efficient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect

Authors:
 [1];  [2];  [3];  [4];  [5];  [2];  [2];  [2];  [3];  [2];  [3];  [2];  [2]
  1. Nanjing Univ. of Posts & Telecommunications, Nanjing (China); Stanford Univ., Stanford, CA (United States)
  2. Stanford Univ., Stanford, CA (United States)
  3. Nanjing Univ. of Posts & Telecommunications, Nanjing (China)
  4. Stanford Univ., Stanford, CA (United States); First Hospital of Shanxi Medical Univ., Taiyuan (China)
  5. Stanford Univ., Stanford, CA (United States); Jiangsu Institute of Nuclear Medicine, Wuxi (China)
Publication Date:
Research Org.:
Stanford Univ., CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Biological and Environmental Research (BER)
OSTI Identifier:
1342723
Grant/Contract Number:  
SC0008397
Resource Type:
Accepted Manuscript
Journal Name:
Advanced Materials
Additional Journal Information:
Journal Volume: 27; Journal Issue: 5; Journal ID: ISSN 0935-9648
Publisher:
Wiley
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; brain tumor; deep tumor imaging; near-infrared-absorption; Perylene-3,4,9,10-tetracarboxylic diimide nanoparticles; photoacoustic imaging

Citation Formats

Fan, Quli, Cheng, Kai, Yang, Zhen, Zhang, Ruiping, Yang, Min, Hu, Xiang, Ma, Xiaowei, Bu, Lihong, Lu, Xiaomei, Xiong, Xiaoxing, Huang, Wei, Zhao, Heng, and Cheng, Zhen. Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice. United States: N. p., 2014. Web. doi:10.1002/adma.201402972.
Fan, Quli, Cheng, Kai, Yang, Zhen, Zhang, Ruiping, Yang, Min, Hu, Xiang, Ma, Xiaowei, Bu, Lihong, Lu, Xiaomei, Xiong, Xiaoxing, Huang, Wei, Zhao, Heng, & Cheng, Zhen. Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice. United States. https://doi.org/10.1002/adma.201402972
Fan, Quli, Cheng, Kai, Yang, Zhen, Zhang, Ruiping, Yang, Min, Hu, Xiang, Ma, Xiaowei, Bu, Lihong, Lu, Xiaomei, Xiong, Xiaoxing, Huang, Wei, Zhao, Heng, and Cheng, Zhen. Thu . "Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice". United States. https://doi.org/10.1002/adma.201402972. https://www.osti.gov/servlets/purl/1342723.
@article{osti_1342723,
title = {Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice},
author = {Fan, Quli and Cheng, Kai and Yang, Zhen and Zhang, Ruiping and Yang, Min and Hu, Xiang and Ma, Xiaowei and Bu, Lihong and Lu, Xiaomei and Xiong, Xiaoxing and Huang, Wei and Zhao, Heng and Cheng, Zhen},
abstractNote = {In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. In this paper, perylene-3,4,9,10-tetracarboxylic diiimide-based near-infrared-absorptive organic nanoparticles are reported as an efficient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect},
doi = {10.1002/adma.201402972},
journal = {Advanced Materials},
number = 5,
volume = 27,
place = {United States},
year = {Thu Nov 06 00:00:00 EST 2014},
month = {Thu Nov 06 00:00:00 EST 2014}
}

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