The increase in animal mortality risk following exposure to sparsely ionizing radiation is not linear quadratic with dose
Abstract
The US government regulates allowable radiation exposures relying, in large part, on the seventh report from the committee to estimate the Biological Effect of Ionizing Radiation (BEIR VII), which estimated that most contemporary exposures- protracted or low-dose, carry 1.5 fold less risk of carcinogenesis and mortality per Gy than acute exposures of atomic bomb survivors. This correction is known as the dose and dose rate effectiveness factor for the life span study of atomic bomb survivors (DDREFLSS). As a result, it was calculated by applying a linear-quadratic dose response model to data from Japanese atomic bomb survivors and a limited number of animal studies.
- Authors:
-
- Northwestern Univ., Chicago, IL (United States)
- Univ. of Chicago, Chicago, IL (United States)
- Univ. of Oklahoma, Norman, OK (United States)
- Publication Date:
- Research Org.:
- Northwestern Univ., Chicago, IL (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC)
- OSTI Identifier:
- 1240244
- Grant/Contract Number:
- SC0001271
- Resource Type:
- Accepted Manuscript
- Journal Name:
- PLoS ONE
- Additional Journal Information:
- Journal Volume: 10; Journal Issue: 12; Journal ID: ISSN 1932-6203
- Publisher:
- Public Library of Science
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; bombs; death rates; radiation exposure; carcinogenesis; dose prediction methods; animal studies; archives; ionizing radiation
Citation Formats
Haley, Benjamin M., Paunesku, Tatjana, Grdina, David J., Woloschak, Gayle E., and Aravindan, Natarajan. The increase in animal mortality risk following exposure to sparsely ionizing radiation is not linear quadratic with dose. United States: N. p., 2015.
Web. doi:10.1371/journal.pone.0140989.
Haley, Benjamin M., Paunesku, Tatjana, Grdina, David J., Woloschak, Gayle E., & Aravindan, Natarajan. The increase in animal mortality risk following exposure to sparsely ionizing radiation is not linear quadratic with dose. United States. https://doi.org/10.1371/journal.pone.0140989
Haley, Benjamin M., Paunesku, Tatjana, Grdina, David J., Woloschak, Gayle E., and Aravindan, Natarajan. Wed .
"The increase in animal mortality risk following exposure to sparsely ionizing radiation is not linear quadratic with dose". United States. https://doi.org/10.1371/journal.pone.0140989. https://www.osti.gov/servlets/purl/1240244.
@article{osti_1240244,
title = {The increase in animal mortality risk following exposure to sparsely ionizing radiation is not linear quadratic with dose},
author = {Haley, Benjamin M. and Paunesku, Tatjana and Grdina, David J. and Woloschak, Gayle E. and Aravindan, Natarajan},
abstractNote = {The US government regulates allowable radiation exposures relying, in large part, on the seventh report from the committee to estimate the Biological Effect of Ionizing Radiation (BEIR VII), which estimated that most contemporary exposures- protracted or low-dose, carry 1.5 fold less risk of carcinogenesis and mortality per Gy than acute exposures of atomic bomb survivors. This correction is known as the dose and dose rate effectiveness factor for the life span study of atomic bomb survivors (DDREFLSS). As a result, it was calculated by applying a linear-quadratic dose response model to data from Japanese atomic bomb survivors and a limited number of animal studies.},
doi = {10.1371/journal.pone.0140989},
journal = {PLoS ONE},
number = 12,
volume = 10,
place = {United States},
year = {Wed Dec 09 00:00:00 EST 2015},
month = {Wed Dec 09 00:00:00 EST 2015}
}
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