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Title: Metazen – metadata capture for metagenomes

Abstract

Background: As the impact and prevalence of large-scale metagenomic surveys grow, so does the acute need for more complete and standards compliant metadata. Metadata (data describing data) provides an essential complement to experimental data, helping to answer questions about its source, mode of collection, and reliability. Metadata collection and interpretation have become vital to the genomics and metagenomics communities, but considerable challenges remain, including exchange, curation, and distribution. Currently, tools are available for capturing basic field metadata during sampling, and for storing, updating and viewing it. These tools are not specifically designed for metagenomic surveys; in particular, they lack the appropriate metadata collection templates, a centralized storage repository, and a unique ID linking system that can be used to easily port complete and compatible metagenomic metadata into widely used assembly and sequence analysis tools. Results: Metazen was developed as a comprehensive framework designed to enable metadata capture for metagenomic sequencing projects. Specifically, Metazen provides a rapid, easy-to-use portal to encourage early deposition of project and sample metadata. Conclusion: Metazen is an interactive tool that aids users in recording their metadata in a complete and valid format. A defined set of mandatory fields captures vital information, while the option to addmore » fields provides flexibility.« less

Authors:
 [1];  [1];  [1];  [1];  [1];  [1]
  1. Univ. of Chicago, Chicago, IL (United States); Argonne National Lab. (ANL), Argonne, IL (United States)
Publication Date:
Research Org.:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1224089
Grant/Contract Number:  
AC02-06CH11357
Resource Type:
Accepted Manuscript
Journal Name:
Standards in Genomic Sciences
Additional Journal Information:
Journal Volume: 9; Journal Issue: 1; Journal ID: ISSN 1944-3277
Publisher:
BioMed Central
Country of Publication:
United States
Language:
English
Subject:
97 MATHEMATICS AND COMPUTING; metadata; metagenomics; collection; software

Citation Formats

Bischof, Jared, Harrison, Travis, Paczian, Tobias, Glass, Elizabeth, Wilke, Andreas, and Meyer, Folker. Metazen – metadata capture for metagenomes. United States: N. p., 2014. Web. doi:10.1186/1944-3277-9-18.
Bischof, Jared, Harrison, Travis, Paczian, Tobias, Glass, Elizabeth, Wilke, Andreas, & Meyer, Folker. Metazen – metadata capture for metagenomes. United States. https://doi.org/10.1186/1944-3277-9-18
Bischof, Jared, Harrison, Travis, Paczian, Tobias, Glass, Elizabeth, Wilke, Andreas, and Meyer, Folker. Mon . "Metazen – metadata capture for metagenomes". United States. https://doi.org/10.1186/1944-3277-9-18. https://www.osti.gov/servlets/purl/1224089.
@article{osti_1224089,
title = {Metazen – metadata capture for metagenomes},
author = {Bischof, Jared and Harrison, Travis and Paczian, Tobias and Glass, Elizabeth and Wilke, Andreas and Meyer, Folker},
abstractNote = {Background: As the impact and prevalence of large-scale metagenomic surveys grow, so does the acute need for more complete and standards compliant metadata. Metadata (data describing data) provides an essential complement to experimental data, helping to answer questions about its source, mode of collection, and reliability. Metadata collection and interpretation have become vital to the genomics and metagenomics communities, but considerable challenges remain, including exchange, curation, and distribution. Currently, tools are available for capturing basic field metadata during sampling, and for storing, updating and viewing it. These tools are not specifically designed for metagenomic surveys; in particular, they lack the appropriate metadata collection templates, a centralized storage repository, and a unique ID linking system that can be used to easily port complete and compatible metagenomic metadata into widely used assembly and sequence analysis tools. Results: Metazen was developed as a comprehensive framework designed to enable metadata capture for metagenomic sequencing projects. Specifically, Metazen provides a rapid, easy-to-use portal to encourage early deposition of project and sample metadata. Conclusion: Metazen is an interactive tool that aids users in recording their metadata in a complete and valid format. A defined set of mandatory fields captures vital information, while the option to add fields provides flexibility.},
doi = {10.1186/1944-3277-9-18},
journal = {Standards in Genomic Sciences},
number = 1,
volume = 9,
place = {United States},
year = {Mon Dec 08 00:00:00 EST 2014},
month = {Mon Dec 08 00:00:00 EST 2014}
}

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Works referenced in this record:

The minimum information about a genome sequence (MIGS) specification
journal, May 2008

  • Field, Dawn; Garrity, George; Gray, Tanya
  • Nature Biotechnology, Vol. 26, Issue 5
  • DOI: 10.1038/nbt1360

The minimum information about a genome sequence (MIGS) specification
journal, May 2008

  • Field, Dawn; Garrity, George; Gray, Tanya
  • Nature Biotechnology, Vol. 26, Issue 5
  • DOI: 10.1038/nbt1360

VAMPS: a website for visualization and analysis of microbial population structures
journal, February 2014

  • Huse, Susan M.; Mark Welch, David B.; Voorhis, Andy
  • BMC Bioinformatics, Vol. 15, Issue 1
  • DOI: 10.1186/1471-2105-15-41

A Standard MIGS/MIMS Compliant XML Schema: Toward the Development of the Genomic Contextual Data Markup Language (GCDML)
journal, June 2008

  • Kottmann, Renzo; Gray, Tanya; Murphy, Sean
  • OMICS: A Journal of Integrative Biology, Vol. 12, Issue 2
  • DOI: 10.1089/omi.2008.0a10

The metagenomics RAST server – a public resource for the automatic phylogenetic and functional analysis of metagenomes
journal, September 2008


IMG/M: the integrated metagenome data management and comparative analysis system
journal, November 2011

  • Markowitz, V. M.; Chen, I. -M. A.; Chu, K.
  • Nucleic Acids Research, Vol. 40, Issue D1
  • DOI: 10.1093/nar/gkr975

Sugars dominate the seagrass rhizosphere
text, January 2022


Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications
journal, May 2011

  • Yilmaz, Pelin; Kottmann, Renzo; Field, Dawn
  • Nature Biotechnology, Vol. 29, Issue 5
  • DOI: 10.1038/nbt.1823

QIIME allows analysis of high-throughput community sequencing data
journal, April 2010

  • Caporaso, J. Gregory; Kuczynski, Justin; Stombaugh, Jesse
  • Nature Methods, Vol. 7, Issue 5
  • DOI: 10.1038/nmeth.f.303

VAMPS: a website for visualization and analysis of microbial population structures
journal, February 2014

  • Huse, Susan M.; Mark Welch, David B.; Voorhis, Andy
  • BMC Bioinformatics, Vol. 15, Issue 1
  • DOI: 10.1186/1471-2105-15-41

The metagenomics RAST server – a public resource for the automatic phylogenetic and functional analysis of metagenomes
journal, September 2008


The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata
journal, December 2011

  • Pagani, I.; Liolios, K.; Jansson, J.
  • Nucleic Acids Research, Vol. 40, Issue D1
  • DOI: 10.1093/nar/gkr1100

IMG/M: the integrated metagenome data management and comparative analysis system
journal, November 2011

  • Markowitz, V. M.; Chen, I. -M. A.; Chu, K.
  • Nucleic Acids Research, Vol. 40, Issue D1
  • DOI: 10.1093/nar/gkr975

Community cyberinfrastructure for Advanced Microbial Ecology Research and Analysis: the CAMERA resource
journal, November 2010

  • Sun, S.; Chen, J.; Li, W.
  • Nucleic Acids Research, Vol. 39, Issue Database
  • DOI: 10.1093/nar/gkq1102

ISA software suite: supporting standards-compliant experimental annotation and enabling curation at the community level
journal, August 2010


Works referencing / citing this record:

Genomes OnLine Database (GOLD) v.6: data updates and feature enhancements
journal, October 2016

  • Mukherjee, Supratim; Stamatis, Dimitri; Bertsch, Jon
  • Nucleic Acids Research, Vol. 45, Issue D1
  • DOI: 10.1093/nar/gkw992

Genomes OnLine Database (GOLD) v.6: data updates and feature enhancements
journal, October 2016

  • Mukherjee, Supratim; Stamatis, Dimitri; Bertsch, Jon
  • Nucleic Acids Research, Vol. 45, Issue D1
  • DOI: 10.1093/nar/gkw992

MG-RAST version 4—lessons learned from a decade of low-budget ultra-high-throughput metagenome analysis
journal, September 2017

  • Meyer, Folker; Bagchi, Saurabh; Chaterji, Somali
  • Briefings in Bioinformatics, Vol. 20, Issue 4
  • DOI: 10.1093/bib/bbx105

Value, but high costs in post-deposition data curation
journal, January 2016


The MG-RAST metagenomics database and portal in 2015
journal, December 2015

  • Wilke, Andreas; Bischof, Jared; Gerlach, Wolfgang
  • Nucleic Acids Research, Vol. 44, Issue D1
  • DOI: 10.1093/nar/gkv1322

The MG-RAST metagenomics database and portal in 2015
journal, December 2015

  • Wilke, Andreas; Bischof, Jared; Gerlach, Wolfgang
  • Nucleic Acids Research, Vol. 44, Issue D1
  • DOI: 10.1093/nar/gkv1322