Fat to muscle ratio measurements with dual energy x-ray absorbtiometry

Chen, A.; Luo, J.; Wang, A.; Broadbent, C.; Zhong, J.; Dilmanian, F. A.; Zafonte, F.; Zhong, Z.

doi:10.1016/j.nima.2015.03.001

Title: Fat to muscle ratio measurements with dual energy x-ray absorbtiometry

Abstract

Accurate measurement of the fat-to-muscle ratio in animal model is important for obesity research. In addition, an efficient way to measure the fat to muscle ratio in animal model using dual-energy absorptiometry is presented in this paper. A radioactive source exciting x-ray fluorescence from a target material is used to provide the two x-ray energies needed. The x-rays, after transmitting through the sample, are measured with an energy-sensitive Ge detector. Phantoms and specimens were measured. The results showed that the method was sensitive to the fat to muscle ratios with good linearity. A standard deviation of a few percent in the fat to muscle ratio could be observed with the x-ray dose of 0.001 mGy.

Authors:

Chen, A. ^[1]; Luo, J. ^[2]; Wang, A. ^[3]; Broadbent, C. ^[4]; Zhong, J. ^[5]; Dilmanian, F. A. ^[6]; Zafonte, F. ^[7]; Zhong, Z. ^[7]

Shenzhen College of International Education; GuangDong (China)
Univ. at Buffalo, Buffalo, NY (United States)
Carnegie Mellon Univ., Pittsburgh, PA (United States)
Columbia Univ., New York, NY (United States)
Dartmouth College, Hanover, NH (United States)
Stony Brook Univ., Stony Brook, NY (United States)
Brookhaven National Lab. (BNL), Upton, NY (United States)

Publication Date:: Sat Mar 14 00:00:00 EDT 2015

Research Org.:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Org.:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

OSTI Identifier:: 1193200

Alternate Identifier(s):: OSTI ID: 1247382

Report Number(s):: BNL-107905-2015-JA
Journal ID: ISSN 0168-9002; R&D Project: LS001

Grant/Contract Number:: SC00112704; AC02-98CH10886; 05–057

Resource Type:: Accepted Manuscript

Journal Name:: Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment

Additional Journal Information:: Journal Volume: 788; Journal Issue: C; Journal ID: ISSN 0168-9002

Publisher:: Elsevier

Country of Publication:: United States

Language:: English

Subject:: 36 MATERIALS SCIENCE; dual energy x-ray; absorptiometry; obesity research; fat-to-muscle ratio

Citation Formats


                    Chen, A., Luo, J., Wang, A., Broadbent, C., Zhong, J., Dilmanian, F. A., Zafonte, F., and Zhong, Z. Fat to muscle ratio measurements with dual energy x-ray absorbtiometry.  United States: N. p., 2015. 
Web.  doi:10.1016/j.nima.2015.03.001.

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                    Chen, A., Luo, J., Wang, A., Broadbent, C., Zhong, J., Dilmanian, F. A., Zafonte, F., & Zhong, Z. Fat to muscle ratio measurements with dual energy x-ray absorbtiometry.  United States.  https://doi.org/10.1016/j.nima.2015.03.001

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                    Chen, A., Luo, J., Wang, A., Broadbent, C., Zhong, J., Dilmanian, F. A., Zafonte, F., and Zhong, Z. Sat .  
"Fat to muscle ratio measurements with dual energy x-ray absorbtiometry".  United States.  https://doi.org/10.1016/j.nima.2015.03.001.  https://www.osti.gov/servlets/purl/1193200.

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@article{osti_1193200,

  title        = {Fat to muscle ratio measurements with dual energy x-ray absorbtiometry},

  author       = {Chen, A. and Luo, J. and Wang, A. and Broadbent, C. and Zhong, J. and Dilmanian, F. A. and Zafonte, F. and Zhong, Z.},

  abstractNote = {Accurate measurement of the fat-to-muscle ratio in animal model is important for obesity research. In addition, an efficient way to measure the fat to muscle ratio in animal model using dual-energy absorptiometry is presented in this paper. A radioactive source exciting x-ray fluorescence from a target material is used to provide the two x-ray energies needed. The x-rays, after transmitting through the sample, are measured with an energy-sensitive Ge detector. Phantoms and specimens were measured. The results showed that the method was sensitive to the fat to muscle ratios with good linearity. A standard deviation of a few percent in the fat to muscle ratio could be observed with the x-ray dose of 0.001 mGy.},

  doi          = {10.1016/j.nima.2015.03.001},

  journal      = {Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment},

  number       = C,

  volume       = 788,

  place        = {United States},

  year         = {Sat Mar 14 00:00:00 EDT 2015},

  month        = {Sat Mar 14 00:00:00 EDT 2015}

}

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https://doi.org/10.1016/j.nima.2015.03.001

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Works referenced in this record:

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Clinical Use of Bone Densitometry: Scientific Review
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Cummings, Steven R.; Bates, David; Black, Dennis M.
JAMA, Vol. 288, Issue 15
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Synchrotron radiation coronary angiography with a dual-beam, dual-detector imaging system
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Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 291, Issue 1-2
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A bent Laue crystal monochromator for monochromatic radiography with an area beam
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Zhong, Z.; Chapman, D.; Thomlinson, W.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 399, Issue 2-3
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Title: Fat to muscle ratio measurements with dual energy x-ray absorbtiometry

Abstract

Citation Formats

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