Modulation of Magnetic Heating via Dipolar Magnetic Interactions in Monodisperse and Crystalline Iron Oxide Nanoparticles
Abstract
Here, we report on the study of heat dissipation power in monodisperse and crystalline magnetite nanoparticles as function of particle and aggregate sizes, magnetic field frequencies (up to 435 kHz) and amplitudes (up to 50 mT), media viscosity and particle concentration. These nanoparticles display specific absorption rate values of few hundreds of WgFe-1 at moderate frequencies (~100 kHz), increasing up to 3632 WgFe-1 at more extreme field conditions (430 kHz and 40 mT) for the largest size. We have found that Néelian relaxation processes are dominant for all nanoparticle sizes, whereas Brownian contribution dominates only for the largest size (22 nm) at high particle concentrations when dipolar interactions enhance the effective magnetic anisotropy. Besides, the particle concentration dependence of the specific absorption rate reflects the importance of magnetic dipolar interactions which strongly depend on aggregate and particle size. Our results show that dipolar interactions tune the effective magnetic anisotropy determining the Néelian and Brownian contributions into SAR values. The possibility of switching between heating mechanisms via dipolar interactions is of great importance towards controlling the heat exposure supplied by IONP as intracellular heating mediators.
- Authors:
-
- Univ. of Cantoblanco, Madrid (Spain). IMDEA nanoscience; Univ. of Cantoblanco, Madrid (Spain). Institute of Materials Science of Madrid-CSIC
- Univ. of Cantoblanco, Madrid (Spain). IMDEA nanoscience; Autonomous University of Madrid, Madrid (Spain)
- Univ. of Cantoblanco, Madrid (Spain). IMDEA Nanoscience
- Univ. of Cantoblanco, Madrid (Spain). IMDEA Nanoscience and Institute of Materials Science of Madrid-CSIC
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Univ. Complutense Madrid (Spain)
- Friedrich Schiller Univ., Jena (Germany)
- Univ. of Cantoblanco, Madrid (Spain). IMDEA Nanoscience; Autonomous University of Madrid, Madrid (Spain)
- Univ. of Cantoblanco, Madrid (Spain). Institute of Materials Science of Madrid-CSIC
- Univ. of Cantoblanco, Madrid (Spain). IMDEA nanoscience ; Univ. of Cantoblanco, Madrid (Spain). Associated Unit of Nanobiotechnology CNB-CSUC & IMDEA Nanoscience
- Publication Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1162068
- Grant/Contract Number:
- AC05-00OR22725
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Journal of Physical Chemistry. C
- Additional Journal Information:
- Journal Volume: 118; Journal Issue: 34; Journal ID: ISSN 1932-7447
- Publisher:
- American Chemical Society
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 77 NANOSCIENCE AND NANOTECHNOLOGY; iron oxide nanoparticles; magnetic heating; magnetic dipolar interactions; magnetic effective anisotropy
Citation Formats
Salas, Gorka, Camarero, Julio, Cabrera, David, Takacs, Hélène, Varela, María, Ludwig, Robert, Dähring, Heidi, Hilger, Ingrid, Miranda, Rodolfo, Morales, María del Puerto, and Teran, Francisco Jose. Modulation of Magnetic Heating via Dipolar Magnetic Interactions in Monodisperse and Crystalline Iron Oxide Nanoparticles. United States: N. p., 2014.
Web. doi:10.1021/jp5041234.
Salas, Gorka, Camarero, Julio, Cabrera, David, Takacs, Hélène, Varela, María, Ludwig, Robert, Dähring, Heidi, Hilger, Ingrid, Miranda, Rodolfo, Morales, María del Puerto, & Teran, Francisco Jose. Modulation of Magnetic Heating via Dipolar Magnetic Interactions in Monodisperse and Crystalline Iron Oxide Nanoparticles. United States. https://doi.org/10.1021/jp5041234
Salas, Gorka, Camarero, Julio, Cabrera, David, Takacs, Hélène, Varela, María, Ludwig, Robert, Dähring, Heidi, Hilger, Ingrid, Miranda, Rodolfo, Morales, María del Puerto, and Teran, Francisco Jose. Wed .
"Modulation of Magnetic Heating via Dipolar Magnetic Interactions in Monodisperse and Crystalline Iron Oxide Nanoparticles". United States. https://doi.org/10.1021/jp5041234. https://www.osti.gov/servlets/purl/1162068.
@article{osti_1162068,
title = {Modulation of Magnetic Heating via Dipolar Magnetic Interactions in Monodisperse and Crystalline Iron Oxide Nanoparticles},
author = {Salas, Gorka and Camarero, Julio and Cabrera, David and Takacs, Hélène and Varela, María and Ludwig, Robert and Dähring, Heidi and Hilger, Ingrid and Miranda, Rodolfo and Morales, María del Puerto and Teran, Francisco Jose},
abstractNote = {Here, we report on the study of heat dissipation power in monodisperse and crystalline magnetite nanoparticles as function of particle and aggregate sizes, magnetic field frequencies (up to 435 kHz) and amplitudes (up to 50 mT), media viscosity and particle concentration. These nanoparticles display specific absorption rate values of few hundreds of WgFe-1 at moderate frequencies (~100 kHz), increasing up to 3632 WgFe-1 at more extreme field conditions (430 kHz and 40 mT) for the largest size. We have found that Néelian relaxation processes are dominant for all nanoparticle sizes, whereas Brownian contribution dominates only for the largest size (22 nm) at high particle concentrations when dipolar interactions enhance the effective magnetic anisotropy. Besides, the particle concentration dependence of the specific absorption rate reflects the importance of magnetic dipolar interactions which strongly depend on aggregate and particle size. Our results show that dipolar interactions tune the effective magnetic anisotropy determining the Néelian and Brownian contributions into SAR values. The possibility of switching between heating mechanisms via dipolar interactions is of great importance towards controlling the heat exposure supplied by IONP as intracellular heating mediators.},
doi = {10.1021/jp5041234},
journal = {Journal of Physical Chemistry. C},
number = 34,
volume = 118,
place = {United States},
year = {Wed Jul 23 00:00:00 EDT 2014},
month = {Wed Jul 23 00:00:00 EDT 2014}
}
Web of Science
Works referenced in this record:
Biomedical Nanomagnetics: A Spin Through Possibilities in Imaging, Diagnostics, and Therapy
journal, July 2010
- Krishnan, Kannan M.
- IEEE Transactions on Magnetics, Vol. 46, Issue 7
Iron oxide-based nanostructures for MRI and magnetic hyperthermia
journal, September 2012
- Hilger, Ingrid; Kaiser, Werner A.
- Nanomedicine, Vol. 7, Issue 9
Magnetic nanoparticles: synthesis, functionalization, and applications in bioimaging and magnetic energy storage
journal, January 2009
- Frey, Natalie A.; Peng, Sheng; Cheng, Kai
- Chemical Society Reviews, Vol. 38, Issue 9
Progress in the preparation of magnetic nanoparticles for applications in biomedicine
journal, November 2009
- Roca, A. G.; Costo, R.; Rebolledo, A. F.
- Journal of Physics D: Applied Physics, Vol. 42, Issue 22
Relationship between physico-chemical properties of magnetic fluids and their heating capacity
journal, September 2013
- Salas, Gorka; Veintemillas-Verdaguer, Sabino; Morales, Maria del Puerto
- International Journal of Hyperthermia, Vol. 29, Issue 8
Different cell responses induced by exposure to maghemite nanoparticles
journal, January 2013
- Luengo, Yurena; Nardecchia, Stefania; Morales, María Puerto
- Nanoscale, Vol. 5, Issue 23
Efficient and safe internalization of magnetic iron oxide nanoparticles: Two fundamental requirements for biomedical applications
journal, May 2014
- Calero, Macarena; Gutiérrez, Lucía; Salas, Gorka
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 4
Visualization of custom-tailored iron oxide nanoparticles chemistry, uptake, and toxicity
journal, January 2012
- Wilkinson, Kai; Ekstrand-Hammarström, Barbro; Ahlinder, Linnea
- Nanoscale, Vol. 4, Issue 23
Cooperative Organization in Iron Oxide Multi-Core Nanoparticles Potentiates Their Efficiency as Heating Mediators and MRI Contrast Agents
journal, November 2012
- Lartigue, Lénaic; Hugounenq, Pierre; Alloyeau, Damien
- ACS Nano, Vol. 6, Issue 12
Theory of proton relaxation induced by superparamagnetic particles
journal, March 1999
- Roch, Alain; Muller, Robert N.; Gillis, Pierre
- The Journal of Chemical Physics, Vol. 110, Issue 11
Dimercaptosuccinic acid-coated magnetite nanoparticles for magnetically guided in vivo delivery of interferon gamma for cancer immunotherapy
journal, April 2011
- Mejías, Raquel; Pérez-Yagüe, Sonia; Gutiérrez, Lucía
- Biomaterials, Vol. 32, Issue 11
Highly water-soluble magnetic iron oxide (Fe3O4) nanoparticles for drug delivery: enhanced in vitro therapeutic efficacy of doxorubicin and MION conjugates
journal, January 2013
- Majeed, Muhammad Irfan; Lu, Qunwei; Yan, Wei
- Journal of Materials Chemistry B, Vol. 1, Issue 22
Clinical hyperthermia of prostate cancer using magnetic nanoparticles: Presentation of a new interstitial technique
journal, November 2005
- Johannsen, M.; Gneveckow, U.; Eckelt, L.
- International Journal of Hyperthermia, Vol. 21, Issue 7
Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme
journal, September 2010
- Maier-Hauff, Klaus; Ulrich, Frank; Nestler, Dirk
- Journal of Neuro-Oncology, Vol. 103, Issue 2
Exchange-coupled magnetic nanoparticles for efficient heat induction
journal, June 2011
- Lee, Jae-Hyun; Jang, Jung-tak; Choi, Jin-sil
- Nature Nanotechnology, Vol. 6, Issue 7
Remote control of ion channels and neurons through magnetic-field heating of nanoparticles
journal, June 2010
- Huang, Heng; Delikanli, Savas; Zeng, Hao
- Nature Nanotechnology, Vol. 5, Issue 8
Inductive heating of ferrimagnetic particles and magnetic fluids: Physical evaluation of their potential for hyperthermia
journal, January 1993
- Jordan, A.; Wust, P.; Fählin, H.
- International Journal of Hyperthermia, Vol. 9, Issue 1
Size-dependent properties of magnetic iron oxidenanocrystals
journal, January 2011
- Demortière, A.; Panissod, P.; Pichon, B. P.
- Nanoscale, Vol. 3, Issue 1
Ultra-large-scale syntheses of monodisperse nanocrystals
journal, November 2004
- Park, Jongnam; An, Kwangjin; Hwang, Yosun
- Nature Materials, Vol. 3, Issue 12
Monodisperse MFe 2 O 4 (M = Fe, Co, Mn) Nanoparticles
journal, January 2004
- Sun, Shouheng; Zeng, Hao; Robinson, David B.
- Journal of the American Chemical Society, Vol. 126, Issue 1
Surfactant Organic Molecules Restore Magnetism in Metal-Oxide Nanoparticle Surfaces
journal, April 2012
- Salafranca, Juan; Gazquez, Jaume; Pérez, Nicolás
- Nano Letters, Vol. 12, Issue 5
Controlled synthesis of uniform magnetite nanocrystals with high-quality properties for biomedical applications
journal, January 2012
- Salas, Gorka; Casado, Cintia; Teran, Francisco J.
- Journal of Materials Chemistry, Vol. 22, Issue 39
Anomalous Magnetic Properties of Nanoparticles Arising from Defect Structures: Topotaxial Oxidation of Fe 1– x O|Fe 3−δ O 4 Core|Shell Nanocubes to Single-Phase Particles
journal, July 2013
- Wetterskog, Erik; Tai, Cheuk-Wai; Grins, Jekabs
- ACS Nano, Vol. 7, Issue 8
Multiplying Magnetic Hyperthermia Response by Nanoparticle Assembling
journal, March 2014
- Serantes, David; Simeonidis, Konstantinos; Angelakeris, Makis
- The Journal of Physical Chemistry C, Vol. 118, Issue 11
Adjustable Hyperthermia Response of Self-Assembled Ferromagnetic Fe-MgO Core-Shell Nanoparticles by Tuning Dipole-Dipole Interactions
journal, May 2012
- Martinez-Boubeta, Carlos; Simeonidis, Konstantinos; Serantes, David
- Advanced Functional Materials, Vol. 22, Issue 17
Learning from Nature to Improve the Heat Generation of Iron-Oxide Nanoparticles for Magnetic Hyperthermia Applications
journal, April 2013
- Martinez-Boubeta, Carlos; Simeonidis, Konstantinos; Makridis, Antonios
- Scientific Reports, Vol. 3, Issue 1
Role of dipolar interaction in magnetic hyperthermia
journal, January 2014
- Landi, Gabriel T.
- Physical Review B, Vol. 89, Issue 1
Modeling magnetic nanoparticle dipole-dipole interactions inside living cells
journal, August 2011
- Lévy, Michael; Gazeau, Florence; Bacri, Jean-Claude
- Physical Review B, Vol. 84, Issue 7
How cellular processing of superparamagnetic nanoparticles affects their magnetic behavior and NMR relaxivity
journal, May 2012
- Lévy, Michael; Wilhelm, Claire; Devaud, Martin
- Contrast Media & Molecular Imaging, Vol. 7, Issue 4
Magnetic hyperthermia efficiency in the cellular environment for different nanoparticle designs
journal, August 2014
- Di Corato, Riccardo; Espinosa, Ana; Lartigue, Lenaic
- Biomaterials, Vol. 35, Issue 24
Heating magnetic fluid with alternating magnetic field
journal, November 2002
- Rosensweig, R. E.
- Journal of Magnetism and Magnetic Materials, Vol. 252
Fe-based nanoparticles as tunable magnetic particle hyperthermia agents
journal, September 2013
- Simeonidis, K.; Martinez-Boubeta, C.; Balcells, Ll.
- Journal of Applied Physics, Vol. 114, Issue 10
Size-Sorted Anionic Iron Oxide Nanomagnets as Colloidal Mediators for Magnetic Hyperthermia
journal, March 2007
- Fortin, Jean-Paul; Wilhelm, Claire; Servais, Jacques
- Journal of the American Chemical Society, Vol. 129, Issue 9
Dynamics of magnetic nanoparticle in a viscous liquid: Application to magnetic nanoparticle hyperthermia
journal, July 2012
- Usov, N. A.; Liubimov, B. Ya.
- Journal of Applied Physics, Vol. 112, Issue 2
The influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cells
journal, February 2009
- Villanueva, Angeles; Cañete, Magdalena; Roca, Alejandro G.
- Nanotechnology, Vol. 20, Issue 11
Influence of a transverse static magnetic field on the magnetic hyperthermia properties and high-frequency hysteresis loops of ferromagnetic FeCo nanoparticles
journal, January 2012
- Mehdaoui, B.; Carrey, J.; Stadler, M.
- Applied Physics Letters, Vol. 100, Issue 5
Accurate determination of the specific absorption rate in superparamagnetic nanoparticles under non-adiabatic conditions
journal, August 2012
- Teran, F. J.; Casado, C.; Mikuszeit, N.
- Applied Physics Letters, Vol. 101, Issue 6
Magnetic Iron Oxide Nanoparticles in 10−40 nm Range: Composition in Terms of Magnetite/Maghemite Ratio and Effect on the Magnetic Properties
journal, March 2011
- Santoyo Salazar, Jaime; Perez, Lucas; de Abril, Oscar
- Chemistry of Materials, Vol. 23, Issue 6
Critical radius for exchange bias in naturally oxidized Fe nanoparticles
journal, August 2006
- Martínez-Boubeta, C.; Simeonidis, K.; Angelakeris, M.
- Physical Review B, Vol. 74, Issue 5, Article No. 054430
Surface and Internal Spin Canting in γ-Fe 2 O 3 Nanoparticles
journal, November 1999
- Morales, M. P.; Veintemillas-Verdaguer, S.; Montero, M. I.
- Chemistry of Materials, Vol. 11, Issue 11
Estimation of blocking temperatures from ZFC/FC curves
journal, August 1999
- Hansen, M. F.; Mørup, S.
- Journal of Magnetism and Magnetic Materials, Vol. 203, Issue 1-3
Optimal Size of Nanoparticles for Magnetic Hyperthermia: A Combined Theoretical and Experimental Study
journal, October 2011
- Mehdaoui, Boubker; Meffre, Anca; Carrey, Julian
- Advanced Functional Materials, Vol. 21, Issue 23
Suitability of commercial colloids for magnetic hyperthermia
journal, May 2009
- Kallumadil, Mathew; Tada, Masaru; Nakagawa, Takashi
- Journal of Magnetism and Magnetic Materials, Vol. 321, Issue 10
Simple models for dynamic hysteresis loop calculations of magnetic single-domain nanoparticles: Application to magnetic hyperthermia optimization
journal, April 2011
- Carrey, J.; Mehdaoui, B.; Respaud, M.
- Journal of Applied Physics, Vol. 109, Issue 8
Increase of magnetic hyperthermia efficiency due to dipolar interactions in low-anisotropy magnetic nanoparticles: Theoretical and experimental results
journal, May 2013
- Mehdaoui, B.; Tan, R. P.; Meffre, A.
- Physical Review B, Vol. 87, Issue 17
Dynamic magnetic hysteresis in single-domain particles with uniaxial anisotropy
journal, November 2010
- Poperechny, I. S.; Raikher, Yu. L.; Stepanov, V. I.
- Physical Review B, Vol. 82, Issue 17
Dynamic and static properties of interacting fine ferromagnetic particles
journal, December 1983
- Chantrell, R. W.; Wohlfarth, E. P.
- Journal of Magnetism and Magnetic Materials, Vol. 40, Issue 1-2
The theory of the Vogel-Fulcher law of spin glasses
journal, October 1981
- Shtrikman, S.; Wohlfarth, E. P.
- Physics Letters A, Vol. 85, Issue 8-9
Predicted time dependence of the switching field for magnetic materials
journal, July 1989
- Victora, R. H.
- Physical Review Letters, Vol. 63, Issue 4
Works referencing / citing this record:
Biologically Targeted Magnetic Hyperthermia: Potential and Limitations
journal, August 2018
- Chang, David; Lim, May; Goos, Jeroen A. C. M.
- Frontiers in Pharmacology, Vol. 9
Experimental Evaluation on the Heating Efficiency of Magnetoferritin Nanoparticles in an Alternating Magnetic Field
journal, October 2019
- Xu, Huangtao; Pan, Yongxin
- Nanomaterials, Vol. 9, Issue 10