Robotic automation of droplet microfluidics

Tran, Tuan M.; Kim, Samuel C.; Modavi, Cyrus; Abate, Adam R.

doi:10.1063/5.0064265

Title: Robotic automation of droplet microfluidics

Journal Article · 02 February 2022 · Biomicrofluidics

DOI: https://doi.org/10.1063/5.0064265 · OSTI ID:2560926

Tran, Tuan M.;

; Modavi, Cyrus;

Droplet microfluidics enables powerful analytic capabilities but often requires workflows involving macro- and microfluidic processing steps that are cumbersome to perform manually. Here, we demonstrate the automation of droplet microfluidics with commercial fluid-handling robotics. The workflows incorporate common microfluidic devices including droplet generators, mergers, and sorters and utilize the robot's native capabilities for thermal control, incubation, and plate scanning. The ability to automate microfluidic devices using commercial fluid handling will speed up the integration of these methods into biological workflows.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). Molecular Foundry

Sponsoring Organization:: National Institutes of Health (NIH); National Science Foundation (NSF); USDOE; USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 2560926

Journal Information:: Biomicrofluidics, Journal Name: Biomicrofluidics Journal Issue: 1 Vol. 16; ISSN 1932-1058

Publisher:: American Institute of PhysicsCopyright Statement

Country of Publication:: United States

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
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Title: Robotic automation of droplet microfluidics

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