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Title: Structural insights into the assembly and regulation of 2′-O RNA methylation by SARS-CoV-2 nsp16/nsp10

Journal Article · · Structure

Not Available

Sponsoring Organization:
USDOE
Grant/Contract Number:
AC02-06CH11357
OSTI ID:
2555892
Journal Information:
Structure, Journal Name: Structure; ISSN 0969-2126
Publisher:
ElsevierCopyright Statement
Country of Publication:
United Kingdom
Language:
English

References (38)

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Structural basis of RNA cap modification by SARS-CoV-2 journal July 2020
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide journal June 2021
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2′-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography journal May 2021
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Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2′- O -methyl transfer by SARS-CoV-2 nsp16 journal June 2021
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Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis journal June 2015
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Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex journal October 2011
Nsp16 shields SARS–CoV ‐2 from efficient MDA5 sensing and IFIT1 ‐mediated restriction journal October 2022
Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2 journal October 2020

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