Impact of developmental methylmercury exposure on avian embryonic development, hatchling growth, and survival

Leaphart, James C.; Chinn, Sarah M.; Beasley, James C.

doi:10.1093/etojnl/vgae032

Title: Impact of developmental methylmercury exposure on avian embryonic development, hatchling growth, and survival

Journal Article · 05 January 2025 · Environmental Toxicology and Chemistry

DOI: https://doi.org/10.1093/etojnl/vgae032 · OSTI ID:2496778

Leaphart, James C.;

; Beasley, James C.

Abstract Methylmercury (MeHg) is a globally ubiquitous and persistent environmental toxicant that negatively affects animal behavior, health, and reproduction. In birds, MeHg is transferred from female to egg, contaminating embryos during sensitive stages of early embryonic development and growth. This toxic exposure in the prenatal environment not only induces mortality but also possible lasting impacts on physiology, health, and survival, even once hatched. The purpose of our study was to further elucidate the negative effects of MeHg exposure during avian embryonic development and explore how such exposure can impact offspring development, growth, and survival, both in ovo and posthatch. To assess this, we experimentally dosed fertile mallard and wood duck eggs with MeHg II chloride and reared developing embryos and ducklings to various endpoints. We found that embryos not only readily accumulated MeHg throughout incubation, but they also displayed varying dose-dependent disparities in body mass and morphometrics, with control individuals being larger during early and late embryonic stages of development (p < 0.05). Furthermore, hatched offspring exposed to MeHg exhibited increasingly slower growth rates between 7 to 10 and 10 to 15 days posthatch (p < 0.05), and were found to have lower survival probabilities both under controlled laboratory conditions (p < 0.005), and in the natural environment (p < 0.05). Our findings on the detrimental effects of MeHg on avian embryos and hatchlings emphasize the need for more proactive means of environmental protection and remediation to protect vulnerable avian populations and the ecosystems they inhabit.

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Sponsoring Organization:: USDOE

OSTI ID:: 2496778

Journal Information:: Environmental Toxicology and Chemistry, Journal Name: Environmental Toxicology and Chemistry; ISSN 0730-7268

Publisher:: Oxford University PressCopyright Statement

Country of Publication:: United States

Language:: English

References (52)

Interactions between methylmercury and selenomethionine injected into mallard eggs Klimstra, Jon D.; Yee, Julie L.; Heinz, Gary H. Environmental Toxicology and Chemistry, Vol. 31, Issue 3 https://doi.org/10.1002/etc.1708	journal	December 2011
Methyl mercury and stable isotopes of nitrogen reveal that a terrestrial spider has a diet of emergent aquatic insects Speir, Shannon L.; Chumchal, Matthew M.; Drenner, Ray W. Environmental Toxicology and Chemistry, Vol. 33, Issue 11 https://doi.org/10.1002/etc.2700	journal	July 2014
Acute embryotoxic effects but no long‐term reproductive effects of in ovo methylmercury exposure in zebra finches (Taeniopygia guttata) Yu, Maria S.; Eng, Margaret L.; Williams, Tony D. Environmental Toxicology and Chemistry, Vol. 35, Issue 6 https://doi.org/10.1002/etc.3307	journal	March 2016
Egg mercury levels decline with the laying sequence in charadriiformes Becker, PeterH. Bulletin of Environmental Contamination and Toxicology, Vol. 48, Issue 5 https://doi.org/10.1007/BF00195999	journal	May 1992
Tissue Mercury Concentrations and Survival of Tree Swallow Embryos, Nestlings and Young Adult Females on a Contaminated Site Taylor, Capwell E.; Cristol, Daniel A. Bulletin of Environmental Contamination and Toxicology, Vol. 95, Issue 4 https://doi.org/10.1007/s00128-015-1643-0	journal	August 2015
Factors Affecting the Toxicity of Methylmercury Injected into Eggs Heinz, G. H.; Hoffman, D. J.; Kondrad, S. L. Archives of Environmental Contamination and Toxicology, Vol. 50, Issue 2 https://doi.org/10.1007/s00244-005-1002-y	journal	November 2005
Species Differences in the Sensitivity of Avian Embryos to Methylmercury Heinz, Gary H.; Hoffman, David J.; Klimstra, Jon D. Archives of Environmental Contamination and Toxicology, Vol. 56, Issue 1 https://doi.org/10.1007/s00244-008-9160-3	journal	April 2008
Hormesis Associated with a Low Dose of Methylmercury Injected into Mallard Eggs Heinz, Gary H.; Hoffman, David J.; Klimstra, Jon D. Archives of Environmental Contamination and Toxicology, Vol. 62, Issue 1 https://doi.org/10.1007/s00244-011-9680-0	journal	May 2011
Marine Birds as Sentinels of Environmental Pollution Burger, Joanna; Gochfeld, Michael EcoHealth, Vol. 1, Issue 3 https://doi.org/10.1007/s10393-004-0096-4	journal	May 2004
Effects of mercury exposure on the reproductive success of tree swallows (Tachycineta bicolor) Brasso, Rebecka L.; Cristol, Daniel A. Ecotoxicology, Vol. 17, Issue 2 https://doi.org/10.1007/s10646-007-0163-z	journal	August 2007
The role of weather in mediating the effect of mercury exposure on reproductive success in tree swallows Hallinger, Kelly K.; Cristol, Daniel A. Ecotoxicology, Vol. 20, Issue 6 https://doi.org/10.1007/s10646-011-0694-1	journal	May 2011
Toxicity of methylmercury injected into eggs of thick-billed murres and arctic terns Braune, Birgit M.; Scheuhammer, Anton M.; Crump, Douglas Ecotoxicology, Vol. 21, Issue 8 https://doi.org/10.1007/s10646-012-0967-3	journal	July 2012
Relationships between blood mercury levels, reproduction, and return rate in a small seabird Pollet, Ingrid L.; Leonard, Marty L.; O’Driscoll, Nelson J. Ecotoxicology, Vol. 26, Issue 1 https://doi.org/10.1007/s10646-016-1745-4	journal	November 2016
Spatial variation in aquatic invertebrate and riparian songbird mercury exposure across a river-reservoir system with a legacy of mercury contamination Jackson, Allyson K.; Eagles-Smith, Collin A.; Emery, Colleen Ecotoxicology, Vol. 29, Issue 8 https://doi.org/10.1007/s10646-019-02043-z	journal	May 2019
Mercury and Growth of Tree Swallows at Acadia National Park, and at Orono, Maine, USA Longcore, Jerry R.; Dineli, Reza; Haines, Terry A. Environmental Monitoring and Assessment, Vol. 126, Issue 1-3 https://doi.org/10.1007/s10661-006-9325-3	journal	October 2006
Factors affecting reproductive performance in captive mallard ducks Stunden, C. E.; Bluhm, C. K.; Cheng, K. M. Theriogenology, Vol. 52, Issue 3 https://doi.org/10.1016/S0093-691X(99)00141-7	journal	August 1999
Methylmercury egg injections: Part 2—Pathology, neurochemistry, and behavior in the avian embryo and hatchling Rutkiewicz, Jennifer; Bradley, Mark; Mittal, Krittika Ecotoxicology and Environmental Safety, Vol. 93 https://doi.org/10.1016/j.ecoenv.2013.04.007	journal	July 2013
Methylmercury egg injections: Part 1-Tissue distribution of mercury in the avian embryo and hatchling Rutkiewicz, Jennifer; Basu, Niladri Ecotoxicology and Environmental Safety, Vol. 93 https://doi.org/10.1016/j.ecoenv.2013.04.008	journal	July 2013
Diet shifts during egg laying: Implications for measuring contaminants in bird eggs Morrissey, Christy A.; Elliott, John E.; Ormerod, Stephen J. Environmental Pollution, Vol. 158, Issue 2 https://doi.org/10.1016/j.envpol.2009.08.040	journal	February 2010
Floodplain methylmercury biomagnification factor higher than that of the contiguous river (South River, Virginia USA) Newman, Michael C.; Xu, Xiaoyu; Condon, Anne Environmental Pollution, Vol. 159, Issue 10 https://doi.org/10.1016/j.envpol.2011.04.045	journal	October 2011
High feather mercury concentrations in the wandering albatross are related to sex, breeding status and trophic ecology with no demographic consequences Bustamante, Paco; Carravieri, Alice; Goutte, Aurélie Environmental Research, Vol. 144 https://doi.org/10.1016/j.envres.2015.10.024	journal	January 2016
Inter- and intraclutch variation in egg mercury levels in marine bird species from the Canadian Arctic Akearok, Jason A.; Hebert, Craig E.; Braune, Birgit M. Science of The Total Environment, Vol. 408, Issue 4 https://doi.org/10.1016/j.scitotenv.2009.11.039	journal	January 2010
How does climate change influence arctic mercury? Stern, Gary A.; Macdonald, Robie W.; Outridge, Peter M. Science of The Total Environment, Vol. 414 https://doi.org/10.1016/j.scitotenv.2011.10.039	journal	January 2012
Pathways and consequences of contaminant flux to Acadian flycatchers ( Empidonax virescens ) in urbanizing landscapes of Ohio, USA Rowse, Linnea M.; Rodewald, Amanda D.; Sullivan, S. Mažeika P. Science of The Total Environment, Vol. 485-486 https://doi.org/10.1016/j.scitotenv.2014.03.095	journal	July 2014
Avian mercury exposure and toxicological risk across western North America: A synthesis Ackerman, Joshua T.; Eagles-Smith, Collin A.; Herzog, Mark P. Science of The Total Environment, Vol. 568 https://doi.org/10.1016/j.scitotenv.2016.03.071	journal	October 2016
Methylmercury exposure in wildlife: A review of the ecological and physiological processes affecting contaminant concentrations and their interpretation Chételat, John; Ackerman, Joshua T.; Eagles-Smith, Collin A. Science of The Total Environment, Vol. 711 https://doi.org/10.1016/j.scitotenv.2019.135117	journal	April 2020
Mercury as a Global Pollutant: Sources, Pathways, and Effects Driscoll, Charles T.; Mason, Robert P.; Chan, Hing Man Environmental Science & Technology, Vol. 47, Issue 10 https://doi.org/10.1021/es305071v	journal	May 2013
Binding of methylmercury chloride to the model peptide, N-acetyl-L-cysteine. Proton magnetic resonance study Sumpson, Paul G.; Hopkins, Ted E.; Haque, Rizwanul The Journal of Physical Chemistry, Vol. 77, Issue 19 https://doi.org/10.1021/j100638a005	journal	September 1973
Binding of methylmercury to ovalbumin as methylmercuric cysteine Magat, Welsonia J.; Sell, Jerry L. Journal of Agricultural and Food Chemistry, Vol. 29, Issue 3 https://doi.org/10.1021/jf00105a028	journal	May 1981
Methylmercury concentrations and production rates across a trophic gradient in the northern Everglades Gilmour, Cynthia C.; Riedel, G. S.; Ederington, M. C. Biogeochemistry, Vol. 40, Issue 2/3, p. 327-345 https://doi.org/10.1023/A:1005972708616	journal	March 1998
Mercury sources, distribution, and bioavailability in the North Pacific Ocean: Insights from data and models: MERCURY IN THE NORTH PACIFIC OCEAN Sunderland, Elsie M.; Krabbenhoft, David P.; Moreau, John W. Global Biogeochemical Cycles, Vol. 23, Issue 2 https://doi.org/10.1029/2008GB003425	journal	May 2009
Osprey: Worldwide Sentinel Species for Assessing and Monitoring Environmental Contamination in Rivers, Lakes, Reservoirs, and Estuaries Grove, Robert A.; Henny, Charles J.; Kaiser, James L. Journal of Toxicology and Environmental Health, Part B, Vol. 12, Issue 1 https://doi.org/10.1080/10937400802545078	journal	January 2009
Behavioral, Morphological, and Biochemical Changes after In Ovo Exposure to Methylmercury in Chicks Carvalho, Márcia C.; Nazari, Evelise M.; Farina, Marcelo Toxicological Sciences, Vol. 106, Issue 1 https://doi.org/10.1093/toxsci/kfn158	journal	August 2008
Altered pairing behaviour and reproductive success in white ibises exposed to environmentally relevant concentrations of methylmercury Frederick, Peter; Jayasena, Nilmini Proceedings of the Royal Society B: Biological Sciences, Vol. 278, Issue 1713 https://doi.org/10.1098/rspb.2010.2189	journal	November 2010
Demographic consequences of heavy metals and persistent organic pollutants in a vulnerable long-lived bird, the wandering albatross Goutte, Aurélie; Barbraud, Christophe; Meillère, Alizée Proceedings of the Royal Society B: Biological Sciences, Vol. 281, Issue 1787 https://doi.org/10.1098/rspb.2013.3313	journal	July 2014
Female‐biased offspring sex ratios in birds at a mercury‐contaminated river Bouland, Andrew J.; White, Ariel E.; Lonabaugh, Kevin P. Journal of Avian Biology, Vol. 43, Issue 3 https://doi.org/10.1111/j.1600-048X.2012.05612.x	journal	April 2012
The Movement of Aquatic Mercury Through Terrestrial Food Webs Cristol, D. A.; Brasso, R. L.; Condon, A. M. Science, Vol. 320, Issue 5874 https://doi.org/10.1126/science.1154082	journal	April 2008
Mercury Methylation by Dissimilatory Iron-Reducing Bacteria Kerin, E. J.; Gilmour, C. C.; Roden, E. Applied and Environmental Microbiology, Vol. 72, Issue 12, p. 7919-7921 https://doi.org/10.1128/AEM.01602-06	journal	October 2006
Global Biogeochemical Cycling of Mercury: A Review Selin, Noelle E. Annual Review of Environment and Resources, Vol. 34, Issue 1 https://doi.org/10.1146/annurev.environ.051308.084314	journal	November 2009
Mercury Reduces Avian Reproductive Success and Imposes Selection: An Experimental Study with Adult- or Lifetime-Exposure in Zebra Finch Varian-Ramos, Claire W.; Swaddle, John P.; Cristol, Daniel A. PLoS ONE, Vol. 9, Issue 4 https://doi.org/10.1371/journal.pone.0095674	journal	April 2014
Wood duck duckling mortality and habitat implications in floodplain systems Davis, J. Brian; Leopold, Bruce D.; Kaminski, Richard M. Wetlands, Vol. 29, Issue 2 https://doi.org/10.1672/08-136.1	journal	June 2009
The Impact of Mercury Exposure on the Common Loon (Gavia immer) Population in the Adirondack Park, New York, USA Schoch, Nina; Glennon, Michale J.; Evers, David C. Waterbirds, Vol. 37, Issue sp1 https://doi.org/10.1675/063.037.sp116	journal	April 2014
Mercury Patterns in wood duck eggs from a Contaminated Reservoir in South Carolina, usa Kennamer, Robert A.; Stout, Jason R.; Jackson, Brian P. Environmental Toxicology and Chemistry, Vol. 24, Issue 7 https://doi.org/10.1897/03-661.1	journal	January 2005
Effects of Methylmercury on Reproduction in American Kestrels Albers, Peter H.; Koterba, Michael T.; Rossmann, Ronald Environmental Toxicology and Chemistry, Vol. 26, Issue 9 https://doi.org/10.1897/06-592R.1	journal	January 2007
Survival of Wood Duck Ducklings and Broods in Mississippi and Alabama Davis, J. Brian; Cox, Robert R.; Kaminski, Richard M. Journal of Wildlife Management, Vol. 71, Issue 2 https://doi.org/10.2193/2005-720	journal	April 2007
Mercury Accumulation in Great Skuas Catharacta skua of Known Age and Sex, and Its Effects Upon Breeding and Survival Thompson, D. R.; Hamer, K. C.; Furness, R. W. The Journal of Applied Ecology, Vol. 28, Issue 2 https://doi.org/10.2307/2404575	journal	August 1991
Survival in Wood Duck Broods McGilvrey, Frank B. The Journal of Wildlife Management, Vol. 33, Issue 1 https://doi.org/10.2307/3799651	journal	January 1969
Methylmercury: Reproductive and Behavioral Effects on Three Generations of Mallard Ducks Heinz, Gary H. The Journal of Wildlife Management, Vol. 43, Issue 2 https://doi.org/10.2307/3800348	journal	April 1979
Food Selection by Wood Ducks in Relation to Breeding Status Drobney, Ronald D.; Fredrickson, Leigh H. The Journal of Wildlife Management, Vol. 43, Issue 1 https://doi.org/10.2307/3800641	journal	January 1979
Foods Consumed by Breeding Mallards on Wetlands of South-Central North Dakota Swanson, George A.; Meyer, Mavis I.; Adomaitis, Vyto A. The Journal of Wildlife Management, Vol. 49, Issue 1 https://doi.org/10.2307/3801871	journal	January 1985
Diets and Food Selection of Female Mallards and Blue-Winged Teal During Spring Migration Tidwell, Paul R.; Webb, Elisabeth B.; Vrtiska, Mark P. Journal of Fish and Wildlife Management, Vol. 4, Issue 1 https://doi.org/10.3996/072012-JFWM-062	journal	June 2013
Methylmercury Accumulation in Tissues and its Effects on Growth and Appetite in Captive Great Egrets Spalding, Marilyn G.; Frederick, Peter C.; McGill, Heather C. Journal of Wildlife Diseases, Vol. 36, Issue 3 https://doi.org/10.7589/0090-3558-36.3.411	journal	July 2000

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