From small changes to big gains: pyridinium-based tetralactam macrocycle for enhanced sugar recognition in water

Zhai, Canjia; Zulueta, Ethan Cross; Mariscal, Alexander; Xu, Chengkai; Cui, Yunpeng; Wang, Xudong; Wu, Huang; Doan, Carson; Wojtas, Lukasz; Zhang, Haixin; Cai, Jianfeng; Ye, Libin; Wang, Kun; Liu, Wenqi

doi:10.1039/D4SC06190J

Title: From small changes to big gains: pyridinium-based tetralactam macrocycle for enhanced sugar recognition in water

Journal Article · 26 November 2024 · Chemical Science

DOI: https://doi.org/10.1039/D4SC06190J · OSTI ID:2476883

^[1]; Zulueta, Ethan Cross ^[1]; Mariscal, Alexander ^[1];

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Department of Chemistry, University of South Florida, Tampa, FL, 33620, USA
Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, 33620, USA
Department of Chemistry, The University of Hong Kong, Hong Kong SAR 999077, China
Department of Physics, University of Miami, Coral Gables, Florida 33146, USA
Department of Physics, University of Miami, Coral Gables, Florida 33146, USA, Department of Chemistry, University of Miami, Coral Gables, Florida 33146, USA

Incorporating pyridinium into an anthracene-based macrocycle significantly enhances its sugar binding affinity by increasing hydrogen bonding and expanding the contact surface area.

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Sponsoring Organization:: USDOE

Grant/Contract Number:: SC0024924

OSTI ID:: 2476883

Journal Information:: Chemical Science, Journal Name: Chemical Science Journal Issue: 46 Vol. 15; ISSN 2041-6520; ISSN CSHCBM

Publisher:: Royal Society of Chemistry (RSC)Copyright Statement

Country of Publication:: United Kingdom

Language:: English

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