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Title: The Addition of Transcriptomics to the Bead-Enabled Accelerated Monophasic Multi-Omics Method: A Step toward Universal Sample Preparation

Journal Article · · Analytical Chemistry
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  1. Biochemistry and Biotechnology Group, Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, United States
  2. Microbial and Biome Sciences Group, Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, United States
  3. Genomics and Bioanalytics Group, Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, United States
+ Show Author Affiliations

Not Available

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE; USDOE Laboratory Directed Research and Development (LDRD) Program; USDOE National Nuclear Security Administration (NNSA)
Grant/Contract Number:
89233218CNA000001
OSTI ID:
2476445
Report Number(s):
LA-UR--24-22005; acs.analchem.4c02835
Journal Information:
Analytical Chemistry, Journal Name: Analytical Chemistry; ISSN 0003-2700
Publisher:
American Chemical SocietyCopyright Statement
Country of Publication:
United States
Language:
English

References (16)

After the Genome—A Brief History of Proteomics journal September 2022
Microcystin-LR aerosol induces inflammatory responses in healthy human primary airway epithelium journal November 2022
Rapid Multi-Omics Sample Preparation for Mass Spectrometry journal January 2023
DNA Binding to the Silica: Cooperative Adsorption in Action journal May 2021
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads journal February 2015
Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling journal September 2016
HISAT: a fast spliced aligner with low memory requirements journal March 2015
Dual extraction of mRNA and lipids from a single biological sample journal May 2018
Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology journal January 2016
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data journal November 2009
The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update journal April 2022
The complete sequence of a human genome journal April 2022
MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses journal May 2016
Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation journal February 2021
Cutadapt removes adapter sequences from high-throughput sequencing reads journal May 2011
Three-in-One Simultaneous Extraction of Proteins, Metabolites and Lipids for Multi-Omics journal April 2021

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37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
extraction
genetics
lipidomics
metabolomics
proteomics