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Title: Toward Smart, Automated Junctional Tourniquets—AI Models to Interpret Vessel Occlusion at Physiological Pressure Points

Journal Article · · Bioengineering

Hemorrhage is the leading cause of preventable death in both civilian and military medicine. Junctional hemorrhages are especially difficult to manage since traditional tourniquet placement is often not possible. Ultrasound can be used to visualize and guide the caretaker to apply pressure at physiological pressure points to stop hemorrhage. However, this process is technically challenging, requiring the vessel to be properly positioned over rigid boney surfaces and applying sufficient pressure to maintain proper occlusion. As a first step toward automating this life-saving intervention, we demonstrate an artificial intelligence algorithm that classifies a vessel as patent or occluded, which can guide a user to apply the appropriate pressure required to stop flow. Neural network models were trained using images captured from a custom tissue-mimicking phantom and an ex vivo swine model of the inguinal region, as pressure was applied using an ultrasound probe with and without color Doppler overlays. Using these images, we developed an image classification algorithm suitable for the determination of patency or occlusion in an ultrasound image containing color Doppler overlay. Separate AI models for both test platforms were able to accurately detect occlusion status in test-image sets to more than 93% accuracy. In conclusion, this methodology can be utilized for guiding and monitoring proper vessel occlusion, which, when combined with automated actuation and other AI models, can allow for automated junctional tourniquet application.

Research Organization:
Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE Office of Science (SC); U.S. Army Medical Research and Development Command
Grant/Contract Number:
SC0014664
OSTI ID:
2471221
Journal Information:
Bioengineering, Journal Name: Bioengineering Journal Issue: 2 Vol. 11; ISSN 2306-5354
Publisher:
MDPICopyright Statement
Country of Publication:
United States
Language:
English

References (46)

Artificial intelligence in medical science: a review journal November 2023
Gauze vs XSTAT in wound packing for hemorrhage control journal July 2015
330 Effectiveness of Common Femoral Artery Compression in Elimination of Popliteal Blood Flow journal October 2016
Point-of Care Ultrasonographically Guided Proximal External Aortic Compression in the Emergency Department journal November 2019
A new xAI framework with feature explainability for tumors decision-making in Ultrasound data: comparing with Grad-CAM journal June 2023
Ultrasound findings of lung ultrasonography in COVID-19: A systematic review journal March 2022
Deep Learning in Medical Ultrasound Analysis: A Review journal April 2019
A review of medical artificial intelligence journal June 2020
Post-Mortem Evaluation of Potentially Survivable Hemorrhagic Death in a Civilian Population journal November 2018
A systematic literature review of artificial intelligence in the healthcare sector: Benefits, challenges, methodologies, and functionalities journal January 2023
Similarity of the Swine Vasculature to the Human Carotid Bifurcation: Analysis of Arterial Diameters journal February 2008
Junctional Hemorrhage Control for Tactical Combat Casualty Care journal June 2017
AI in health and medicine journal January 2022
An image classification deep-learning algorithm for shrapnel detection from ultrasound images journal May 2022
Comparison of Three Junctional Tourniquets Using a Randomized Trial Design journal August 2018
Stop the Bleed Education Consortium: Education program content and delivery recommendations journal January 2018
The effectiveness of junctional tourniquets: A systematic review and meta-analysis journal March 2019
United States military fatalities during Operation New Dawn journal May 2021
Detection of pneumothorax on ultrasound using artificial intelligence journal November 2022
Death on the battlefield (2001–2011): Implications for the future of combat casualty care journal January 2012
A Predictive Text System for Medical Recommendations in Telemedicine: A Deep Learning Approach in the Arabic Context journal January 2021
You Only Look Once: Unified, Real-Time Object Detection conference June 2016
MobileNetV2: Inverted Residuals and Linear Bottlenecks conference June 2018
Grad-CAM: Visual Explanations from Deep Networks via Gradient-Based Localization conference October 2017
Tumor Detection in Automated Breast Ultrasound Using 3-D CNN and Prioritized Candidate Aggregation journal January 2019
Haemostatic dressings in prehospital care journal November 2012
Martial arts technique for control of severe external bleeding journal January 2019
The functional vascular anatomy of the swine for research journal April 2021
Automatic ovarian tumors recognition system based on ensemble convolutional neural network with ultrasound imaging journal November 2022
Prehospital control of life-threatening truncal and junctional haemorrhage is the ultimate challenge in optimizing trauma care; a review of treatment options and their applicability in the civilian trauma setting journal September 2016
Deep-learning based detection of COVID-19 using lung ultrasound imagery journal August 2021
Performance of Junctional Tourniquets in Normal Human Volunteers journal December 2014
An extended focused assessment with sonography in trauma ultrasound tissue-mimicking phantom for developing automated diagnostic technologies journal November 2023
Ultrasound Image Classification of Thyroid Nodules Based on Deep Learning journal July 2022
Multi-Stage Classification of Retinal OCT Using Multi-Scale Ensemble Deep Architecture journal July 2023
A New Fuzzy-Based Classification Method for Use in Smart/Precision Medicine journal July 2023
AI-Enabled, Ultrasound-Guided Handheld Robotic Device for Femoral Vascular Access journal December 2021
Comparison of Ultrasound Image Classifier Deep Learning Algorithms for Shrapnel Detection journal May 2022
Using an Ultrasound Tissue Phantom Model for Hybrid Training of Deep Learning Models for Shrapnel Detection journal October 2022
Development and Characterization of an Ex Vivo Testing Platform for Evaluating Automated Central Vascular Access Device Performance journal August 2022
A Review of the Role of Artificial Intelligence in Healthcare journal June 2023
Use of Haemostatic Devices for the Control of Junctional and Abdominal Traumatic Haemorrhage: A Systematic Review journal February 2022
Junctional Tourniquet Training Experience journal January 2015
Testing of Junctional Tourniquets by Medics of the Israeli Defense Force in Control of Simulated Groin Hemorrhage journal January 2016
Junctional Tourniquet Use During Combat Operations in Afghanistan: The Prehospital Trauma Registry Experience journal January 2018
Artificial intelligence in healthcare: transforming the practice of medicine journal July 2021