Charting the coordinative landscape of the 18 F–Sc/ 44 Sc/ 177 Lu triad with the tri-aza-cyclononane (tacn) scaffold

Kelderman, Cormac A. A.; Glaser, Owen M.; Whetter, Jennifer N.; Aluicio-Sarduy, Eduardo; Mixdorf, Jason C.; Sanders, Kyana M.; Guzei, Ilia A.; Barnhart, Todd E.; Engle, Jonathan W.; Boros, Eszter

doi:10.1039/D4SC04735D

Title: Charting the coordinative landscape of the ¹⁸ F–Sc/ ⁴⁴ Sc/ ¹⁷⁷ Lu triad with the tri-aza-cyclononane (tacn) scaffold

Journal Article · 06 November 2024 · Chemical Science

DOI: https://doi.org/10.1039/D4SC04735D · OSTI ID:2461644

^[1]; Glaser, Owen M. ^[1]; Whetter, Jennifer N. ^[1]; Aluicio-Sarduy, Eduardo ^[2]; Mixdorf, Jason C. ^[2];

^[3]; Guzei, Ilia A. ^[3]; Barnhart, Todd E. ^[2]; Engle, Jonathan W. ^[2];

^[1]

Department of Chemistry, Stony Brook University, Stony Brook, New York 11790, USA, Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA
Department of Medical Physics, University of Wisconsin-Madison, Wisconsin 53705, USA
Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA

Computational, spectroscopic and radiochemical screening reveals essential ligand characteristics for the in vivo compatibility of ⁴⁴ Sc-/ ¹⁷⁷ Lu/ ¹⁸ F–Sc coordination complexes.

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Sponsoring Organization:: USDOE

OSTI ID:: 2461644

Journal Information:: Chemical Science, Journal Name: Chemical Science Journal Issue: 43 Vol. 15; ISSN 2041-6520; ISSN CSHCBM

Publisher:: Royal Society of Chemistry (RSC)Copyright Statement

Country of Publication:: United Kingdom

Language:: English

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Title: Charting the coordinative landscape of the ¹⁸ F–Sc/ ⁴⁴ Sc/ ¹⁷⁷ Lu triad with the tri-aza-cyclononane (tacn) scaffold