Linking secretion and cytoskeleton in immunity– a case for Arabidopsis TGNap1

Bhandari, Deepak D.; Brandizzi, Federica

doi:10.1002/bies.202400150

Title: Linking secretion and cytoskeleton in immunity– a case for Arabidopsis TGNap1

Journal Article · 19 September 2024 · BioEssays

DOI: https://doi.org/10.1002/bies.202400150 · OSTI ID:2447500

Bhandari, Deepak D. ^[1];

^[1]

Michigan State University, East Lansing, MI (United States)

In plants, robust defense depends on the efficient and resilient trafficking supply chains to the site of pathogen attack. Though the importance of intracellular trafficking in plant immunity has been well established, a lack of clarity remains regarding the contribution of the various trafficking pathways in transporting immune-related proteins. We have recently identified a trans-Golgi network protein, TGN-ASSOCIATED PROTEIN 1 (TGNap1), which functionally links post-Golgi vesicles with the cytoskeleton to transport immunity-related proteins in the model plant species Arabidopsis thaliana. We propose new hypotheses on the various functional implications of TGNap1 and then elaborate on the surprising heterogeneity of TGN vesicles during immunity revealed by the discovery of TGNap1 and other TGN-associated proteins in recent years.

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Research Organization:: Chicago Office, Argonne, IL (United States)

Sponsoring Organization:: AgBioResearch, Michigan State University; USDOE; USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences & Biosciences Division (CSGB)

Grant/Contract Number:: AC02-76SF00515; FG02-91ER20021

OSTI ID:: 2447500

Journal Information:: BioEssays, Journal Name: BioEssays Journal Issue: 11 Vol. 46; ISSN 0265-9247; ISSN 1521-1878

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
TGNap1
cytoskeleton
cytoskeleton-organelle bridging proteins
immune secretion
innate immunity
trans-Golgi network

Title: Linking secretion and cytoskeleton in immunity– a case for Arabidopsis TGNap1

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