Effects of AI-2 quorum sensing inhibitors on mitigating bacterial contamination in bioethanol production

Tian, Jun; Liang, Yuhai; Ragauskas, Arthur J.; Zhong, Yanming; Lin, Yunqin

doi:10.1016/j.biombioe.2024.107211

Title: Effects of AI-2 quorum sensing inhibitors on mitigating bacterial contamination in bioethanol production

Journal Article · 20 April 2024 · Biomass and Bioenergy

DOI: https://doi.org/10.1016/j.biombioe.2024.107211 · OSTI ID:2447264

Tian, Jun ^[1]; Liang, Yuhai ^[2];

^[3]; Zhong, Yanming ^[1];

^[4]

South China Agricultural University (China)
South China Agricultural University (China); Guangdong Laboratory for Lingnan Modern Agriculture (China)
Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). Joint Institute for Biological Sciences (JIBS)
South China Agricultural University (China); Guangdong Laboratory for Lingnan Modern Agriculture (China); Univ. of Tennessee, Knoxville, TN (United States)

Here, in this paper, the activities of signal molecule AI-2 in the sole fermentation of Lactiplantibacillus plantarum and co-fermentation of Saccharomyces cerevisiae and L. plantarum were investigated. Co-fermentation of S. cerevisiae and L. plantarum was found to reduce L. plantarum to secrete AI-2. Three AI-2 quorum sensing inhibitors (DMHF (2,5-Dimethyl-4-hydroxy-3-(2H)-furanone), D-Rib (D-Ribose), and D-Gal (D-Galactosamine)) were added to the co-fermentation system to further interrupt the growth of L. plantarum. It was found that 0.2 g/L DMHF or 18.0 g/L D-Gal could mainly decrease the activity of AI-2 by 38 % and 36 %, respectively, and significantly inhibit the biofilm formation of L. plantarum. Moreover, the ethanol concentrations of the co-fermentation trials added with 0.2 g/L DMHF or 18.0 g/L D-Gal were 14 % and 103 % higher than that of the control, respectively, within 30 h of fermentation. This study provides basic data for the novel prevention of L. plantarum contamination in bioethanol production via quorum sensing control, which is meaningful for the environmental protection and the sustainable development of bioethanol industry.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC05-00OR22725

OSTI ID:: 2447264

Journal Information:: Biomass and Bioenergy, Journal Name: Biomass and Bioenergy Vol. 184; ISSN 0961-9534

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

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09 BIOMASS FUELS
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Title: Effects of AI-2 quorum sensing inhibitors on mitigating bacterial contamination in bioethanol production

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