Wireless Frequency‐Multiplexed Acoustic Array‐Based Acoustofluidics

Li, Jiali; Bo, Luyu; Li, Teng; Zhao, Penghui; Du, Yingshan; Cai, Bowen; Shen, Liang; Sun, Wujin; Zhou, Wei; Tian, Zhenhua

doi:10.1002/admt.202400572

Title: Wireless Frequency‐Multiplexed Acoustic Array‐Based Acoustofluidics

Journal Article · 24 July 2024 · Advanced Materials Technologies

DOI: https://doi.org/10.1002/admt.202400572 · OSTI ID:2406499

Li, Jiali ^[1]; Bo, Luyu ^[1]; Li, Teng ^[1]; Zhao, Penghui ^[2]; Du, Yingshan ^[3]; Cai, Bowen ^[1]; Shen, Liang ^[1]; Sun, Wujin ^[2]; Zhou, Wei ^[4];

^[1]

Department of Mechanical Engineering Virginia Polytechnic Institute and State University Blacksburg VA 24060 USA
Department of Biological System Engineering Virginia Polytechnic Institute and State University Blacksburg VA 24060 USA
Department of Biomedical Engineering and Science Virginia Polytechnic Institute and State University Blacksburg VA 24060 USA
Bradley Department of Electrical and Computer Engineering Virginia Polytechnic Institute and State University Blacksburg VA 24060 USA

Abstract Acoustofluidics has shown great potential in enabling on‐chip technologies for driving liquid flows and manipulating particles and cells for engineering, chemical, and biomedical applications. To introduce on‐demand liquid sample processing and micro/nano‐object manipulation functions to wearable and embeddable electronics, wireless acoustofluidic chips are highly desired. This paper presents wireless acoustofluidic chips to generate acoustic waves carrying sufficient energy and achieve key acoustofluidic functions, including arranging particles and cells, generating fluid streaming, and enriching in‐droplet particles. To enable these functions, the wireless acoustofluidic chips leverage mechanisms, including inductive coupling‐based wireless power transfer (WPT), frequency multiplexing‐based control of multiple acoustic waves, and the resultant acoustic radiation and drag forces. For validation, the wirelessly generated acoustic waves are measured using laser vibrometry when different materials (e.g., bone, tissue, and hand) are inserted between the WPT transmitter and receiver. Moreover, the wireless acoustofluidic chips successfully arrange nanoparticles into different patterns, align cells into parallel pearl chains, generate streaming, and enrich in‐droplet microparticles. This research is anticipated to facilitate the development of embeddable wireless on‐chip flow generators, wearable sensors with liquid sample processing functions, and implantable devices with flow generation and acoustic stimulation abilities for engineering, veterinary, and biomedical applications.

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Sponsoring Organization:: USDOE

Grant/Contract Number:: NONE; NE0009187

OSTI ID:: 2406499

Journal Information:: Advanced Materials Technologies, Journal Name: Advanced Materials Technologies Journal Issue: 23 Vol. 9; ISSN 2365-709X

Publisher:: Wiley Blackwell (John Wiley & Sons)Copyright Statement

Country of Publication:: United States

Language:: English

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