Electrochemistry of flavin-based electron bifurcation: ‘Current’ past and ‘potential’ futures

Imran, Syed Muhammad Saad; Wiley, Seth A.; Lubner, Carolyn E.

doi:10.1016/j.coelec.2024.101536

Title: Electrochemistry of flavin-based electron bifurcation: ‘Current’ past and ‘potential’ futures

Journal Article · 01 October 2024 · Current Opinion in Electrochemistry

DOI: https://doi.org/10.1016/j.coelec.2024.101536 · OSTI ID:2361162

;

Not Available

View Journal Article

Cite

Export

Save

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC36-08GO28308

OSTI ID:: 2361162

Journal Information:: Current Opinion in Electrochemistry, Journal Name: Current Opinion in Electrochemistry Journal Issue: C Vol. 47; ISSN 2451-9103

Publisher:: ElsevierCopyright Statement

Country of Publication:: United Kingdom

Language:: English

References (68)

Redox bifurcations: Mechanisms and importance to life now, and at its origin: A widespread means of energy conversion in biology unfolds… Nitschke, Wolfgang; Russell, Michael J. BioEssays, Vol. 34, Issue 2 https://doi.org/10.1002/bies.201100134	journal	November 2011
Versatility and specificity in flavoenzymes: Control mechanisms of flavin reactivity Miura, Retsu The Chemical Record, Vol. 1, Issue 3 https://doi.org/10.1002/tcr.1007	journal	January 2001
Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands Hagen, W. R.; Silva, P. J.; Amorim, M. A. JBIC Journal of Biological Inorganic Chemistry, Vol. 5, Issue 4 https://doi.org/10.1007/PL00021452	journal	August 2000
Spectroscopic and biochemical insight into an electron-bifurcating [FeFe] hydrogenase Chongdar, Nipa; Pawlak, Krzysztof; Rüdiger, Olaf JBIC Journal of Biological Inorganic Chemistry, Vol. 25, Issue 1 https://doi.org/10.1007/s00775-019-01747-1	journal	December 2019
Spectroscopic characterization of the iron-sulfur cluster in Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase Oñate, Y. A.; Vollmer, S. J.; Switzer, R. L. Journal of Biological Chemistry, Vol. 264, Issue 31 https://doi.org/10.1016/S0021-9258(18)51476-9	journal	November 1989
Potentiometric and electron nuclear double resonance properties of the two spin forms of the [4Fe-4S]+ cluster in the novel ferredoxin from the hyperthermophilic archaebacterium Pyrococcus furiosus. Park, J. B.; Fan, C. L.; Hoffman, B. M. Journal of Biological Chemistry, Vol. 266, Issue 29 https://doi.org/10.1016/S0021-9258(18)55004-3	journal	October 1991
The Absorption Spectra of Iron-Flavoproteins Rajagopalan, K. V.; Handler, Philip Journal of Biological Chemistry, Vol. 239, Issue 5 https://doi.org/10.1016/S0021-9258(18)91344-X	journal	May 1964
The novel tungsten-iron-sulfur protein of the hyperthermophilic archaebacterium, Pyrococcus furiosus, is an aldehyde ferredoxin oxidoreductase. Evidence for its participation in a unique glycolytic pathway Mukund, S.; Adams, M. W. Journal of Biological Chemistry, Vol. 266, Issue 22 https://doi.org/10.1016/S0021-9258(18)98669-2	journal	August 1991
Spectral deconvolution of electron-bifurcating flavoproteins Ortiz, Steve; Niks, Dimitri; Vigil, Wayne Methods in Enzymology, Vol. 685, p. 531-550 https://doi.org/10.1016/bs.mie.2023.03.011	book	April 2023
Magnetic circular dichroism of hemoproteins with in situ control of electrochemical potential: “MOTTLE” Marritt, Sophie J.; van Wonderen, Jessica H.; Cheesman, Myles R. Analytical Biochemistry, Vol. 359, Issue 1 https://doi.org/10.1016/j.ab.2006.08.017	journal	December 2006
A three-dimensional printed cell for rapid, low-volume spectroelectrochemistry Brisendine, Joseph M.; Mutter, Andrew C.; Cerda, Jose F. Analytical Biochemistry, Vol. 439, Issue 1 https://doi.org/10.1016/j.ab.2013.03.036	journal	August 2013
Energy conservation via electron bifurcating ferredoxin reduction and proton/Na+ translocating ferredoxin oxidation Buckel, Wolfgang; Thauer, Rudolf K. Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1827, Issue 2 https://doi.org/10.1016/j.bbabio.2012.07.002	journal	February 2013
The role of thermodynamic features on the functional activity of electron bifurcating enzymes Wise, Courtney E.; Ledinina, Anastasia E.; Yuly, Jonathon L. Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1862, Issue 4 https://doi.org/10.1016/j.bbabio.2021.148377	journal	April 2021
Electron bifurcation Peters, John W.; Miller, Anne-Frances; Jones, Anne K. Current Opinion in Chemical Biology, Vol. 31 https://doi.org/10.1016/j.cbpa.2016.03.007	journal	April 2016
Modelling the voltammetry of adsorbed enzymes and molecular catalysts Fourmond, Vincent; Léger, Christophe Current Opinion in Electrochemistry, Vol. 1, Issue 1 https://doi.org/10.1016/j.coelec.2016.11.002	journal	February 2017
Contrasting roles for two conserved arginines: Stabilizing flavin semiquinone or quaternary structure, in bifurcating electron transfer flavoproteins Mohamed-Raseek, Nishya; Miller, Anne-Frances Journal of Biological Chemistry, Vol. 298, Issue 4 https://doi.org/10.1016/j.jbc.2022.101733	journal	April 2022
Rapid-reaction kinetics of the butyryl-CoA dehydrogenase component of the electron-bifurcating crotonyl-CoA-dependent NADH:ferredoxin oxidoreductase from Megasphaera elsdenii Vigil, Wayne; Nguyen, Derek; Niks, Dimitri Journal of Biological Chemistry, Vol. 299, Issue 7 https://doi.org/10.1016/j.jbc.2023.104853	journal	July 2023
Rapid-reaction kinetics of the bifurcating NAD+-dependent NADPH:ferredoxin oxidoreductase NfnI from Pyrococcus furiosus Ortiz, Steve; Niks, Dimitri; Wiley, Seth Journal of Biological Chemistry, Vol. 299, Issue 12 https://doi.org/10.1016/j.jbc.2023.105403	journal	December 2023
Zero-valent iron enhanced methane production of anaerobic digestion by reinforcing microbial electron bifurcation coupled with direct inter-species electron transfer Zhang, Pengshuai; Zhang, Jingxin; Zhang, Tengyu Water Research, Vol. 255 https://doi.org/10.1016/j.watres.2024.121428	journal	May 2024
The ethanol pathway from Thermoanaerobacterium saccharolyticum improves ethanol production in Clostridium thermocellum Hon, Shuen; Olson, Daniel G.; Holwerda, Evert K. Metabolic Engineering, Vol. 42 https://doi.org/10.1016/j.ymben.2017.06.011	journal	July 2017
Preservation of NADH Voltammetry for Enzyme-Modified Electrodes Based on Dehydrogenase Hayes, Mark A.; Kuhr, Werner G. Analytical Chemistry, Vol. 71, Issue 9 https://doi.org/10.1021/ac980354x	journal	March 1999
QSoas: A Versatile Software for Data Analysis Fourmond, Vincent Analytical Chemistry, Vol. 88, Issue 10 https://doi.org/10.1021/acs.analchem.6b00224	journal	May 2016
Characterization of the Membrane-Associated Electron-Bifurcating Flavoenzyme EtfABCX from the Hyperthermophilic Bacterium Thermotoga maritima Ge, Xiaoxuan; Schut, Gerrit J.; Tran, Jessica Biochemistry, Vol. 62, Issue 24 https://doi.org/10.1021/acs.biochem.3c00473	journal	December 2023
In Situ / Operando Electrocatalyst Characterization by X-ray Absorption Spectroscopy Timoshenko, Janis; Roldan Cuenya, Beatriz Chemical Reviews, Vol. 121, Issue 2 https://doi.org/10.1021/acs.chemrev.0c00396	journal	September 2020
Flavin-Based Electron Bifurcation, A New Mechanism of Biological Energy Coupling Buckel, Wolfgang; Thauer, Rudolf K. Chemical Reviews, Vol. 118, Issue 7 https://doi.org/10.1021/acs.chemrev.7b00707	journal	February 2018
Insight into the Redox Behavior of the [4Fe–4S] Subcluster in [FeFe] Hydrogenases Rodríguez-Maciá, Patricia; Breuer, Nina; DeBeer, Serena ACS Catalysis, Vol. 10, Issue 21 https://doi.org/10.1021/acscatal.0c02771	journal	October 2020
Mechanism of Hydrogen Sulfide-Dependent Inhibition of FeFe Hydrogenase Felbek, Christina; Arrigoni, Federica; de Sancho, David ACS Catalysis, Vol. 11, Issue 24 https://doi.org/10.1021/acscatal.1c04838	journal	December 2021
A Variable-Temperature Direct Electrochemical Study of Metalloproteins from Hyperthermophilic Microorganisms Involved in Hydrogen Production from Pyruvate Smith, Eugene T.; Blamey, Jenny M.; Zhou, Zhi H. Biochemistry, Vol. 34, Issue 21 https://doi.org/10.1021/bi00021a030	journal	May 1995
In Situ X-ray Absorption Spectroscopy Investigation of a Bifunctional Manganese Oxide Catalyst with High Activity for Electrochemical Water Oxidation and Oxygen Reduction Gorlin, Yelena; Lassalle-Kaiser, Benedikt; Benck, Jesse D. Journal of the American Chemical Society, Vol. 135, Issue 23 https://doi.org/10.1021/ja3104632	journal	June 2013
Reaction of Thiosulfate Dehydrogenase with a Substrate Mimic Induces Dissociation of the Cysteine Heme Ligand Giving Insights into the Mechanism of Oxidative Catalysis Jenner, Leon P.; Crack, Jason C.; Kurth, Julia M. Journal of the American Chemical Society, Vol. 144, Issue 40 https://doi.org/10.1021/jacs.2c06062	journal	September 2022
Molecular Basis of the Electron Bifurcation Mechanism in the [FeFe]-Hydrogenase Complex HydABC Katsyv, Alexander; Kumar, Anuj; Saura, Patricia Journal of the American Chemical Society, Vol. 145, Issue 10 https://doi.org/10.1021/jacs.2c11683	journal	February 2023
Retuning the Catalytic Bias and Overpotential of a [NiFe]-Hydrogenase via a Single Amino Acid Exchange at the Electron Entry/Exit Site Adamson, Hope; Robinson, Martin; Wright, John J. Journal of the American Chemical Society, Vol. 139, Issue 31 https://doi.org/10.1021/jacs.7b03611	journal	July 2017
His-Ligation to the [4Fe–4S] Subcluster Tunes the Catalytic Bias of [FeFe] Hydrogenase Rodríguez-Maciá, Patricia; Kertess, Leonie; Burnik, Jan Journal of the American Chemical Society, Vol. 141, Issue 1 https://doi.org/10.1021/jacs.8b11149	journal	November 2018
Nature of biological electron transfer Moser, Christopher C.; Keske, Jonathan M.; Warncke, Kurt Nature, Vol. 355, Issue 6363 https://doi.org/10.1038/355796a0	journal	February 1992
Natural engineering principles of electron tunnelling in biological oxidation–reduction Page, Christopher C.; Moser, Christopher C.; Chen, Xiaoxi Nature, Vol. 402, Issue 6757 https://doi.org/10.1038/46972	journal	November 1999
Reversible redox energy coupling in electron transfer chains Osyczka, Artur; Moser, Christopher C.; Daldal, Fevzi Nature, Vol. 427, Issue 6975 https://doi.org/10.1038/nature02242	journal	February 2004
Mechanistic insights into energy conservation by flavin-based electron bifurcation Lubner, Carolyn E.; Jennings, David P.; Mulder, David W. Nature Chemical Biology, Vol. 13, Issue 6 https://doi.org/10.1038/nchembio.2348	journal	April 2017
The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile Demmer, Julius K.; Pal Chowdhury, Nilanjan; Selmer, Thorsten Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/s41467-017-01746-3	journal	November 2017
The Sporomusa type Nfn is a novel type of electron-bifurcating transhydrogenase that links the redox pools in acetogenic bacteria Kremp, Florian; Roth, Jennifer; Müller, Volker Scientific Reports, Vol. 10, Issue 1 https://doi.org/10.1038/s41598-020-71038-2	journal	September 2020
Influence of electrode potential, pH and NAD+ concentration on the electrochemical NADH regeneration Aamer, Emad; Thöming, Jorg; Baune, Michael Scientific Reports, Vol. 12, Issue 1 https://doi.org/10.1038/s41598-022-20508-w	journal	September 2022
Redox hydrogels with adjusted redox potential for improved efficiency in Z-scheme inspired biophotovoltaic cells Hartmann, Volker; Kothe, Tim; Pöller, Sascha Phys. Chem. Chem. Phys., Vol. 16, Issue 24 https://doi.org/10.1039/C4CP00380B	journal	January 2014
Probing biological redox chemistry with large amplitude Fourier transformed ac voltammetry Adamson, Hope; Bond, Alan M.; Parkin, Alison Chemical Communications, Vol. 53, Issue 69 https://doi.org/10.1039/C7CC03870D	journal	January 2017
Protein film electrochemical EPR spectroscopy as a technique to investigate redox reactions in biomolecules Abdiaziz, Kaltum; Salvadori, Enrico; Sokol, Katarzyna P. Chemical Communications, Vol. 55, Issue 60 https://doi.org/10.1039/C9CC03212F	journal	January 2019
Electron bifurcation: progress and grand challenges Yuly, Jonathon L.; Lubner, Carolyn E.; Zhang, Peng Chemical Communications, Vol. 55, Issue 79 https://doi.org/10.1039/C9CC05611D	journal	January 2019
The crystalline state as a dynamic system: IR microspectroscopy under electrochemical control for a [NiFe] hydrogenase Ash, Philip A.; Kendall-Price, Sophie E. T.; Evans, Rhiannon M. Chemical Science, Vol. 12, Issue 39 https://doi.org/10.1039/D1SC01734A	journal	January 2021
The mechanism of inhibition by H2 of H2-evolution by hydrogenases Fourmond, Vincent; Baffert, Carole; Sybirna, Kateryna Chemical Communications, Vol. 49, Issue 61 https://doi.org/10.1039/c3cc43297a	journal	January 2013
Universal free-energy landscape produces efficient and reversible electron bifurcation Yuly, J. L.; Zhang, P.; Lubner, C. E. Proceedings of the National Academy of Sciences, Vol. 117, Issue 35 https://doi.org/10.1073/pnas.2010815117	journal	August 2020
An uncharacteristically low-potential flavin governs the energy landscape of electron bifurcation Wise, Courtney E.; Ledinina, Anastasia E.; Mulder, David W. Proceedings of the National Academy of Sciences, Vol. 119, Issue 12 https://doi.org/10.1073/pnas.2117882119	journal	March 2022
Ultrafast photooxidation of protein-bound anionic flavin radicals Zhuang, Bo; Ramodiharilafy, Rivo; Liebl, Ursula Proceedings of the National Academy of Sciences, Vol. 119, Issue 8 https://doi.org/10.1073/pnas.2118924119	journal	February 2022
Ferredoxin reduction by hydrogen with iron functions as an evolutionary precursor of flavin-based electron bifurcation Brabender, Max; Henriques Pereira, Delfina P.; Mrnjavac, Natalia Proceedings of the National Academy of Sciences, Vol. 121, Issue 13 https://doi.org/10.1073/pnas.2318969121	journal	March 2024
Equilibrium and ultrafast kinetic studies manipulating electron transfer: A short-lived flavin semiquinone is not sufficient for electron bifurcation Hoben, John P.; Lubner, Carolyn E.; Ratzloff, Michael W. Journal of Biological Chemistry, Vol. 292, Issue 34 https://doi.org/10.1074/jbc.M117.794214	journal	June 2017
The catalytic mechanism of electron-bifurcating electron transfer flavoproteins (ETFs) involves an intermediary complex with NAD ⁺ Schut, Gerrit J.; Mohamed-Raseek, Nishya; Tokmina-Lukaszewska, Monika Journal of Biological Chemistry, Vol. 294, Issue 9 https://doi.org/10.1074/jbc.RA118.005653	journal	December 2018
Heme ligation and redox chemistry in two bacterial thiosulfate dehydrogenase (TsdA) enzymes Jenner, Leon P.; Kurth, Julia M.; van Helmont, Sebastian Journal of Biological Chemistry, Vol. 294, Issue 47 https://doi.org/10.1074/jbc.RA119.010084	journal	November 2019
Modulations of the reduction potentials of flavin‐based electron bifurcation complexes and semiquinone stabilities are key to control directional electron flow Sucharitakul, Jeerus; Buttranon, Supacha; Wongnate, Thanyaporn The FEBS Journal, Vol. 288, Issue 3 https://doi.org/10.1111/febs.15343	journal	May 2020
The electron‐bifurcating FeFe‐hydrogenase Hnd is involved in ethanol metabolism in Desulfovibrio fructosovorans grown on pyruvate Payne, Natalie; Kpebe, Arlette; Guendon, Chloé Molecular Microbiology, Vol. 117, Issue 4 https://doi.org/10.1111/mmi.14881	journal	February 2022
Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase Feng, Xiang; Schut, Gerrit J.; Haja, Dominik K. Science Advances, Vol. 8, Issue 8 https://doi.org/10.1126/sciadv.abm7546	journal	February 2022
Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction Wagner, Tristan; Koch, Jürgen; Ermler, Ulrich Science, Vol. 357, Issue 6352 https://doi.org/10.1126/science.aan0425	journal	August 2017
NADP+ Reduction with Reduced Ferredoxin and NADP+ Reduction with NADH Are Coupled via an Electron-Bifurcating Enzyme Complex in Clostridium kluyveri Wang, S.; Huang, H.; Moll, J. Journal of Bacteriology, Vol. 192, Issue 19 https://doi.org/10.1128/JB.00612-10	journal	July 2010
Energy Conservation via Electron-Transferring Flavoprotein in Anaerobic Bacteria Herrmann, G.; Jayamani, E.; Mai, G. Journal of Bacteriology, Vol. 190, Issue 3 https://doi.org/10.1128/JB.01422-07	journal	November 2007
Elucidating the Process of Activation of Methyl-Coenzyme M Reductase Prakash, D.; Wu, Y.; Suh, S. -J. Journal of Bacteriology, Vol. 196, Issue 13 https://doi.org/10.1128/JB.01658-14	journal	April 2014
A Ferredoxin- and F ₄₂₀ H ₂ -Dependent, Electron-Bifurcating, Heterodisulfide Reductase with Homologs in the Domains Bacteria and Archaea Yan, Zhen; Wang, Mingyu; Ferry, James G. mBio, Vol. 8, Issue 1 https://doi.org/10.1128/mBio.02285-16	journal	February 2017
Determination of Flavin Potential in Proteins by Xanthine/Xanthine Oxidase Method Maklashina, Elena; Cecchini, Gary BIO-PROTOCOL, Vol. 10, Issue 7 https://doi.org/10.21769/BioProtoc.3571	journal	January 2020
Origin and Evolution of Flavin-Based Electron Bifurcating Enzymes Poudel, Saroj; Dunham, Eric C.; Lindsay, Melody R. Frontiers in Microbiology, Vol. 9 https://doi.org/10.3389/fmicb.2018.01762	journal	August 2018
An Abundant and Diverse New Family of Electron Bifurcating Enzymes With a Non-canonical Catalytic Mechanism Schut, Gerrit J.; Haja, Dominik K.; Feng, Xiang Frontiers in Microbiology, Vol. 13 https://doi.org/10.3389/fmicb.2022.946711	journal	July 2022
An essential role of the reversible electron-bifurcating hydrogenase Hnd for ethanol oxidation in Solidesulfovibrio fructosivorans Kpebe, Arlette; Guendon, Chloé; Payne, Natalie Frontiers in Microbiology, Vol. 14 https://doi.org/10.3389/fmicb.2023.1139276	journal	March 2023
Obligate autotrophy at the thermodynamic limit of life in a new acetogenic bacterium Frolov, Evgenii N.; Elcheninov, Alexander G.; Gololobova, Alexandra V. Frontiers in Microbiology, Vol. 14 https://doi.org/10.3389/fmicb.2023.1185739	journal	May 2023
Site-Differentiated Iron–Sulfur Cluster Ligation Affects Flavin-Based Electron Bifurcation Activity Wise, Courtney E.; Ledinina, Anastasia E.; Lubner, Carolyn E. Metabolites, Vol. 12, Issue 9 https://doi.org/10.3390/metabo12090823	journal	September 2022
Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase Furlan, Chris; Chongdar, Nipa; Gupta, Pooja eLife, Vol. 11 https://doi.org/10.7554/eLife.79361	journal	August 2022

Similar Records

Origin and Evolution of Flavin-Based Electron Bifurcating Enzymes

Journal Article · 2018 · Frontiers in Microbiology · OSTI ID:1462762

Poudel, Saroj; Dunham, Eric C.; Lindsay, Melody R.; +4 more

Mechanistic insights into energy conservation by flavin-based electron bifurcation

Journal Article · 2017 · Nature Chemical Biology · OSTI ID:1358334

Lubner, Carolyn E.; Jennings, David P.; Mulder, David W.; +13 more

An uncharacteristically low-potential flavin governs the energy landscape of electron bifurcation

Journal Article · 2022 · Proceedings of the National Academy of Sciences of the United States of America · OSTI ID:1854951

Wise, Courtney E.; Ledinina, Anastasia E.; Mulder, David W.; +4 more

Title: Electrochemistry of flavin-based electron bifurcation: ‘Current’ past and ‘potential’ futures

Citation Formats

References (68)

Similar Records

Related Subjects