Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

Yuan, Taolin; Kumar, Surinder; Skinner, Mary E.; Victor-Joseph, Ryan; Abuaita, Majd; Keijer, Jaap; Zhang, Jessica; Kunkel, Thaddeus J.; Liu, Yanghan; Petrunak, Elyse M.; Saunders, Thomas L.; Lieberman, Andrew P.; Stuckey, Jeanne A.; Neamati, Nouri; Al-Murshedi, Fathiya; Alfadhel, Majid; Spelbrink, Johannes N.; Rodenburg, Richard; de Boer, Vincent C. J.; Lombard, David B.

doi:10.1016/j.isci.2024.109991

Title: Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

Journal Article · 01 June 2024 · iScience

DOI: https://doi.org/10.1016/j.isci.2024.109991 · OSTI ID:2352519

Yuan, Taolin; Kumar, Surinder; Skinner, Mary E.; Victor-Joseph, Ryan; Abuaita, Majd; Keijer, Jaap; Zhang, Jessica; Kunkel, Thaddeus J.; Liu, Yanghan; Petrunak, Elyse M.; Saunders, Thomas L.; Lieberman, Andrew P.; Stuckey, Jeanne A.; Neamati, Nouri; Al-Murshedi, Fathiya; Alfadhel, Majid; Spelbrink, Johannes N.; Rodenburg, Richard; de Boer, Vincent C. J.;

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Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: AC02-06CH11357

OSTI ID:: 2352519

Journal Information:: iScience, Journal Name: iScience Journal Issue: 6 Vol. 27; ISSN 2589-0042

Publisher:: ElsevierCopyright Statement

Country of Publication:: Netherlands

Language:: English

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