Plasma–liquid interactions in the presence of organic matter—A perspective

Stapelmann, Katharina; Gershman, Sophia; Miller, Vandana

doi:10.1063/5.0203125

Title: Plasma–liquid interactions in the presence of organic matter—A perspective

Journal Article · 25 April 2024 · Journal of Applied Physics

DOI: https://doi.org/10.1063/5.0203125 · OSTI ID:2352452

^[1];

^[2];

^[3]

North Carolina State University, Raleigh, NC (United States)
Princeton Plasma Physics Laboratory (PPPL), Princeton, NJ (United States)
Drexel Univ., Philadelphia, PA (United States)

As investigations in the biomedical applications of plasma advance, a demand for describing safe and efficacious delivery of plasma is emerging. It is quite clear that not all plasmas are “equal” for all applications. This Perspective discusses limitations of the existing parameters used to define plasma in context of the need for the “right plasma” at the “right dose” for each “disease system.” The validity of results extrapolated from in vitro studies to preclinical and clinical applications is discussed. We make a case for studying the whole system as a single unit, in situ. Furthermore, we argue that while plasma-generated chemical species are the proposed key effectors in biological systems, the contribution of physical effectors (electric fields, surface charging, dielectric properties of target, changes in gap electric fields, etc.) must not be ignored.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Princeton Plasma Physics Laboratory (PPPL), Princeton, NJ (United States)

Sponsoring Organization:: USDOE; National Science Foundation (NSF); National Institutes of Health (NIH)

Grant/Contract Number:: SC0021329; SC0023235; AC02-09CH11466; SC0024539

OSTI ID:: 2352452

Alternate ID(s):: OSTI ID: 2537937

Journal Information:: Journal of Applied Physics, Journal Name: Journal of Applied Physics Journal Issue: 16 Vol. 135; ISSN 0021-8979

Publisher:: American Institute of Physics (AIP)Copyright Statement

Country of Publication:: United States

Language:: English

References (137)

Analysis of Grounded Substrate Effects on Cold Atmospheric Plasma Jet Irradiation of Cellular and Animal models Schweigert, I.; Alexandrov, A.; Zakrevsky, D. Journal of Physics: Conference Series, Vol. 1698, Issue 1 https://doi.org/10.1088/1742-6596/1698/1/012010	journal	December 2020
Defining ROS in Biology and Medicine Li, Y. Robert; Trush, Michael Reactive Oxygen Species, Vol. 1, Issue 1 https://doi.org/10.20455/ros.2016.803	journal	January 2016
Nanosecond-Pulsed DBD Plasma-Generated Reactive Oxygen Species Trigger Immunogenic Cell Death in A549 Lung Carcinoma Cells through Intracellular Oxidative Stress Lin, Abraham; Truong, Billy; Patel, Sohil International Journal of Molecular Sciences, Vol. 18, Issue 5 https://doi.org/10.3390/ijms18050966	journal	May 2017
Thiol chemistry and specificity in redox signaling Winterbourn, Christine C.; Hampton, Mark B. Free Radical Biology and Medicine, Vol. 45, Issue 5 https://doi.org/10.1016/j.freeradbiomed.2008.05.004	journal	September 2008
Toxicity and Immunogenicity in Murine Melanoma following Exposure to Physical Plasma-Derived Oxidants Bekeschus, Sander; Rödder, Katrin; Fregin, Bob Oxidative Medicine and Cellular Longevity, Vol. 2017 https://doi.org/10.1155/2017/4396467	journal	January 2017
Stabilization of liquid instabilities with ionized gas jets Park, Sanghoo; Choe, Wonho; Lee, Hyungyu Nature, Vol. 592, Issue 7852 https://doi.org/10.1038/s41586-021-03359-9	journal	March 2021
Physical plasma-treated saline promotes an immunogenic phenotype in CT26 colon cancer cells in vitro and in vivo Freund, Eric; Liedtke, Kim Rouven; van der Linde, Julia Scientific Reports, Vol. 9, Issue 1 https://doi.org/10.1038/s41598-018-37169-3	journal	January 2019
Molecular dynamics simulations of cancer cell membrane electroporation under the plasma electric field effect Wang, Huichao; Zhao, Tong; Wang, Zichen Plasma Processes and Polymers, Vol. 20, Issue 2 https://doi.org/10.1002/ppap.202200159	journal	November 2022
Analysis of the effects of complex electrode geometries on the energy deposition and temporally and spatially averaged electric field measurements of surface dielectric barrier discharges Trosan, Duncan; Walther, Patrick; McLaughlin, Stephen Plasma Processes and Polymers, Vol. 21, Issue 2 https://doi.org/10.1002/ppap.202300133	journal	September 2023
Measuring plasma-generated ^· OH and O atoms in liquid using EPR spectroscopy and the non-selectivity of the HTA assay Myers, B.; Ranieri, P.; Smirnova, T. Journal of Physics D: Applied Physics, Vol. 54, Issue 14 https://doi.org/10.1088/1361-6463/abd9a6	journal	January 2021
Manmade Electromagnetic Fields and Oxidative Stress—Biological Effects and Consequences for Health Schuermann, David; Mevissen, Meike International Journal of Molecular Sciences, Vol. 22, Issue 7 https://doi.org/10.3390/ijms22073772	journal	April 2021
Self-organized patterns by a DC pin liquid anode discharge in ambient air: Effect of liquid types on formation Zhang, Shiqiang; Dufour, Thierry Physics of Plasmas, Vol. 25, Issue 7 https://doi.org/10.1063/1.5030099	journal	July 2018
Self-rotating dc atmospheric-pressure discharge over a water-surface electrode: regimes of operation Wilson, Alyssa; Staack, David; Farouk, Tanvir Plasma Sources Science and Technology, Vol. 17, Issue 4 https://doi.org/10.1088/0963-0252/17/4/045001	journal	August 2008
Reactive oxygen species at phospholipid bilayers: Distribution, mobility and permeation Cordeiro, Rodrigo M. Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1838, Issue 1 https://doi.org/10.1016/j.bbamem.2013.09.016	journal	January 2014
Introducing adaptive cold atmospheric plasma: The perspective of adaptive cold plasma cancer treatments based on real-time electrochemical impedance spectroscopy Lin, Li; Hou, Zichao; Yao, Xiaoliang Physics of Plasmas, Vol. 27, Issue 6 https://doi.org/10.1063/5.0003528	journal	June 2020
Transport and accumulation of plasma generated species in aqueous solution Verlackt, C. C. W.; Van Boxem, W.; Bogaerts, A. Physical Chemistry Chemical Physics, Vol. 20, Issue 10 https://doi.org/10.1039/C7CP07593F	journal	January 2018
Physics of plasma jets and interaction with surfaces: review on modelling and experiments Viegas, Pedro; Slikboer, Elmar; Bonaventura, Zdenek Plasma Sources Science and Technology, Vol. 31, Issue 5 https://doi.org/10.1088/1361-6595/ac61a9	journal	May 2022
Data-driven prediction of the output composition of an atmospheric pressure plasma jet Lin, Li; Gershman, Sophia; Raitses, Yevgeny Journal of Physics D: Applied Physics, Vol. 57, Issue 1 https://doi.org/10.1088/1361-6463/acfcc7	journal	October 2023
A review of recent investigations into electrical conduction and breakdown of dielectric liquids Swan, D. W. British Journal of Applied Physics, Vol. 13, Issue 5 https://doi.org/10.1088/0508-3443/13/5/304	journal	May 1962
Differential dielectric responses of chondrocyte and Jurkat cells in electromanipulation buffers Sabuncu, Ahmet C.; Asmar, Anthony J.; Stacey, Michael W. ELECTROPHORESIS, Vol. 36, Issue 13 https://doi.org/10.1002/elps.201500119	journal	June 2015
Cellular response to oxidative stress: Signaling for suicide and survival Martindale, Jennifer L.; Holbrook, Nikki J. Journal of Cellular Physiology, Vol. 192, Issue 1 https://doi.org/10.1002/jcp.10119	journal	June 2002
Cold Atmospheric Plasma (CAP) Changes Gene Expression of Key Molecules of the Wound Healing Machinery and Improves Wound Healing In Vitro and In Vivo Arndt, Stephanie; Unger, Petra; Wacker, Eva PLoS ONE, Vol. 8, Issue 11 https://doi.org/10.1371/journal.pone.0079325	journal	November 2013
The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology Graves, David B. Journal of Physics D: Applied Physics, Vol. 45, Issue 26 https://doi.org/10.1088/0022-3727/45/26/263001	journal	June 2012
Cold Plasma in Medicine and Healthcare: The New Frontier in Low Temperature Plasma Applications Laroussi, Mounir Frontiers in Physics, Vol. 8 https://doi.org/10.3389/fphy.2020.00074	journal	March 2020
Plasma–liquid interactions: an experiment and simulation study on plasma dynamic behaviors near the gas–liquid interfacial layer Yang, Qi; Qiao, Jun-Jie; Cheng, He Plasma Sources Science and Technology, Vol. 32, Issue 9 https://doi.org/10.1088/1361-6595/acf8f0	journal	September 2023
Filamentary, patterned, and diffuse barrier discharges Kogelschatz, U. IEEE Transactions on Plasma Science, Vol. 30, Issue 4 https://doi.org/10.1109/TPS.2002.804201	journal	August 2002
Determination of electrophysiological properties of human monocytes and THP-1 cells by dielectrophoresis Mohamed, Rafeezul; Azhar Abdul Razak, Mohd; Adib Kadri, Nahrizul Biomedical Research and Therapy, Vol. 6, Issue 3 https://doi.org/10.15419/bmrat.v6i3.527	journal	March 2019
ROS production in phagocytes: why, when, and where? Dupré-Crochet, Sophie; Erard, Marie; Nüβe, Oliver Journal of Leukocyte Biology, Vol. 94, Issue 4 https://doi.org/10.1189/jlb.1012544	journal	October 2013
Clinical experience with cold plasma in the treatment of locally advanced head and neck cancer Metelmann, Hans-Robert; Seebauer, Christian; Miller, Vandana Clinical Plasma Medicine, Vol. 9 https://doi.org/10.1016/j.cpme.2017.09.001	journal	March 2018
The penetration and concentration of solvated electrons and hydroxyl radicals at a plasma-liquid interface Rumbach, Paul; Bartels, David M.; Go, David B. Plasma Sources Science and Technology, Vol. 27, Issue 11 https://doi.org/10.1088/1361-6595/aaed07	journal	November 2018
The influence of partial surface discharging on the electrical characterization of DBDs Peeters, F. J. J.; van de Sanden, M. C. M. Plasma Sources Science and Technology, Vol. 24, Issue 1 https://doi.org/10.1088/0963-0252/24/1/015016	journal	December 2014
Treatment of phenylalanine and tyrosine in phosphate‐buffered saline by plasma‐supplied oxygen atoms: Chemical characterization and bactericidal effects Jirásek, Vít; Tarabová, Barbora; Lukeš, Petr Plasma Processes and Polymers, Vol. 19, Issue 11 https://doi.org/10.1002/ppap.202200079	journal	June 2022
Visualization of Plasma-Induced Liquid Flow Using KI–Starch and PIV Mitsugi, Fumiaki; Kusumegi, Shota; Nishida, Keisuke IEEE Transactions on Plasma Science, Vol. 49, Issue 1 https://doi.org/10.1109/TPS.2020.2986775	journal	January 2021
Redox Regulation of Cell Survival Trachootham, Dunyaporn; Lu, Weiqin; Ogasawara, Marcia A. Antioxidants & Redox Signaling, Vol. 10, Issue 8 https://doi.org/10.1089/ars.2007.1957	journal	August 2008
Ion energies delivered by negative and positive ionization waves to flat dielectric surfaces Babaeva, Natalia Yu; Naidis, George V. Plasma Sources Science and Technology, Vol. 29, Issue 9 https://doi.org/10.1088/1361-6595/abb2ea	journal	September 2020
Dielectric-Barrier Discharges: Their History, Discharge Physics, and Industrial Applications Kogelschatz, Ulrich Plasma Chemistry and Plasma Processing, Vol. 23, Issue 1, p. 1-46 https://doi.org/10.1023/A:1022470901385	journal	March 2003
NADPH Oxidases: Redox Regulators of Stem Cell Fate and Function Maraldi, Tullia; Angeloni, Cristina; Prata, Cecilia Antioxidants, Vol. 10, Issue 6 https://doi.org/10.3390/antiox10060973	journal	June 2021
Reactive Oxygen Species: Not Omnipresent but Important in Many Locations Herb, Marc; Gluschko, Alexander; Schramm, Michael Frontiers in Cell and Developmental Biology, Vol. 9 https://doi.org/10.3389/fcell.2021.716406	journal	September 2021
Inclusion of Biological Targets in the Analysis of Electrical Characteristics of Non-Thermal Plasma Discharge Sutter, Julia; Brettschneider, Jascha; Mamchur, Sara Plasma, Vol. 6, Issue 3 https://doi.org/10.3390/plasma6030040	journal	September 2023
The role of a dielectric barrier in single-filament discharge over a water surface Höft, H.; Kettlitz, M.; Brandenburg, R. Journal of Applied Physics, Vol. 129, Issue 4 https://doi.org/10.1063/5.0035186	journal	January 2021
The 2022 Plasma Roadmap: low temperature plasma science and technology Adamovich, I.; Agarwal, S.; Ahedo, E. Journal of Physics D: Applied Physics, Vol. 55, Issue 37 https://doi.org/10.1088/1361-6463/ac5e1c	journal	July 2022
Mimicking of Human Body Electrical Characteristic for Easier Translation of Plasma Biomedical Studies to Clinical Applications Stancampiano, A.; Chung, T. -H.; Dozias, S. IEEE Transactions on Radiation and Plasma Medical Sciences, Vol. 4, Issue 3 https://doi.org/10.1109/TRPMS.2019.2936667	journal	May 2020
Effects of initial surfactant concentration on plasma-induced liquid flows Kawasaki, Toshiyuki; Kamasaki, Masahiro; Takeuchi, Nozomi Journal of Applied Physics, Vol. 130, Issue 24 https://doi.org/10.1063/5.0071217	journal	December 2021
Electrical properties of breast cancer cells from impedance measurement of cell suspensions Qiao, G.; Duan, W.; Chatwin, C. Journal of Physics: Conference Series, Vol. 224 https://doi.org/10.1088/1742-6596/224/1/012081	journal	April 2010
Influence of electric potential-induced by atmospheric pressure plasma on cell response Okumura, Takamasa; Chang, Chia-Hsing; Koga, Kazunori Scientific Reports, Vol. 13, Issue 1 https://doi.org/10.1038/s41598-023-42976-4	journal	September 2023
XXIII. Experiments on air. Cavendish, Henry Philosophical Transactions of the Royal Society of London, Vol. 75, p. 372-384 https://doi.org/10.1098/rstl.1785.0023	journal	December 1785
Effect of head group and lipid tail oxidation in the cell membrane revealed through integrated simulations and experiments Yusupov, M.; Wende, K.; Kupsch, S. Scientific Reports, Vol. 7, Issue 1 https://doi.org/10.1038/s41598-017-06412-8	journal	July 2017
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology Sies, Helmut; Belousov, Vsevolod V.; Chandel, Navdeep S. Nature Reviews Molecular Cell Biology, Vol. 23, Issue 7 https://doi.org/10.1038/s41580-022-00456-z	journal	February 2022
Mechanism for action of electromagnetic fields on cells Panagopoulos, Dimitris J.; Karabarbounis, Andreas; Margaritis, Lukas H. Biochemical and Biophysical Research Communications, Vol. 298, Issue 1 https://doi.org/10.1016/S0006-291X(02)02393-8	journal	October 2002
Effect of dielectric and conductive targets on plasma jet behaviour and thin film properties Wang, Ruixue; Xu, Hui; Zhao, Yong Journal of Physics D: Applied Physics, Vol. 52, Issue 7 https://doi.org/10.1088/1361-6463/aaf4c8	journal	December 2018
Non-Thermal Plasma in Contact with Water: The Origin of Species Gorbanev, Yury; O'Connell, Deborah; Chechik, Victor Chemistry - A European Journal, Vol. 22, Issue 10 https://doi.org/10.1002/chem.201503771	journal	February 2016
Effects of high voltage nanosecond electric pulses on eukaryotic cells (in vitro): A systematic review Batista Napotnik, Tina; Reberšek, Matej; Vernier, P. Thomas Bioelectrochemistry, Vol. 110 https://doi.org/10.1016/j.bioelechem.2016.02.011	journal	August 2016
Low-temperature plasmas in contact with liquids—a review of recent progress and challenges Kovačević, Vesna V.; Sretenović, Goran B.; Obradović, Bratislav M. Journal of Physics D: Applied Physics, Vol. 55, Issue 47 https://doi.org/10.1088/1361-6463/ac8a56	journal	September 2022
Can the effect of cold physical plasma-derived oxidants be transported via thiol group oxidation? Heusler, Thea; Bruno, Giuliana; Bekeschus, Sander Clinical Plasma Medicine, Vol. 14 https://doi.org/10.1016/j.cpme.2019.100086	journal	June 2019
The essential role of the plasma sheath in plasma–liquid interaction and its applications—A perspective Vanraes, Patrick; Bogaerts, Annemie Journal of Applied Physics, Vol. 129, Issue 22 https://doi.org/10.1063/5.0044905	journal	June 2021
Interaction of an atmospheric pressure plasma jet with grounded and floating metallic targets: simulations and experiments Viegas, Pedro; Hofmans, Marlous; van Rooij, Olivier Plasma Sources Science and Technology, Vol. 29, Issue 9 https://doi.org/10.1088/1361-6595/aba7ec	journal	September 2020
Effect of fatty acid saturation in membrane lipid bilayers on simple diffusion in the presence of ethanol at high concentrations Mizoguchi, Haruhiko; Hara, Shodo Journal of Fermentation and Bioengineering, Vol. 81, Issue 5 https://doi.org/10.1016/0922-338X(96)85141-5	journal	January 1996
Effect of oxidative stress on plasma membrane fluidity of THP-1 induced macrophages de la Haba, Carlos; Palacio, José R.; Martínez, Paz Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1828, Issue 2 https://doi.org/10.1016/j.bbamem.2012.08.013	journal	February 2013
Leucine modifications by He/O₂ plasma treatment in phosphate-buffered saline: bactericidal effects and chemical characterization Jirásek, Vít; Koval’ová, Zuzana; Tarabová, Barbora Journal of Physics D: Applied Physics, Vol. 54, Issue 50 https://doi.org/10.1088/1361-6463/ac252e	journal	September 2021
Effect of dielectric target properties on plasma surface ionization wave propagation Morsell, Joshua; Bhatt, Naman; Dechant, Corey Journal of Physics D: Applied Physics, Vol. 56, Issue 14 https://doi.org/10.1088/1361-6463/acbfc9	journal	March 2023
Escherichia colicellular responses to exposure to atmospheric‐pressure dielectric barrier discharge plasma‐treated N‐acetylcysteine solution Ercan, U. K.; Sen, B.; Brooks, A. D. Journal of Applied Microbiology, Vol. 125, Issue 2 https://doi.org/10.1111/jam.13777	journal	May 2018
RF-field interactions with biological systems: Electrical properties and biophysical mechanisms Schwan, H. P.; Foster, K. R. Proceedings of the IEEE, Vol. 68, Issue 1 https://doi.org/10.1109/PROC.1980.11589	journal	January 1980
Treating hard‐to‐heal skin and nail onychomycosis of diabetic foot with plasma therapy Terabe, Yuta; Kaneko, Nobuhito; Ando, Hiroshi Dermatologic Therapy, Vol. 34, Issue 6 https://doi.org/10.1111/dth.15127	journal	September 2021
The Influence of Gas–Liquid Interfacial Transport Theory on Numerical Modelling of Plasma Activation of Water Silsby, J. A.; Simon, S.; Walsh, J. L. Plasma Chemistry and Plasma Processing, Vol. 41, Issue 5 https://doi.org/10.1007/s11090-021-10182-7	journal	May 2021
Outside Front Cover: Plasma Process. Polym. 3/2022 Veronico, Valeria; Favia, Pietro; Fracassi, Francesco Plasma Processes and Polymers, Vol. 19, Issue 3 https://doi.org/10.1002/ppap.202270007	journal	March 2022
Cells Electrical Characterization: Dielectric Properties, Mixture, and Modeling Theories Nasir, Nida; Al Ahmad, Mahmoud Journal of Engineering, Vol. 2020 https://doi.org/10.1155/2020/9475490	journal	January 2020
Oxidative stress: a concept in redox biology and medicine Sies, Helmut Redox Biology, Vol. 4 https://doi.org/10.1016/j.redox.2015.01.002	journal	April 2015
Plasma surface ionization wave interactions with single channels Morsell, Joshua; Trosan, Duncan; Stapelmann, Katharina Plasma Sources Science and Technology, Vol. 32, Issue 9 https://doi.org/10.1088/1361-6595/acf9c9	journal	September 2023
Chemical transformations and transport phenomena at interfaces Hao, Hongxia; Ruiz Pestana, Luis; Qian, Jin WIREs Computational Molecular Science, Vol. 13, Issue 2 https://doi.org/10.1002/wcms.1639	journal	October 2022
The interaction between electromagnetic fields at megahertz, gigahertz and terahertz frequencies with cells, tissues and organisms: risks and potential Romanenko, Sergii; Begley, Ryan; Harvey, Alan R. Journal of The Royal Society Interface, Vol. 14, Issue 137 https://doi.org/10.1098/rsif.2017.0585	journal	December 2017
Intracellular effect of ultrashort electrical pulses Schoenbach, Karl H.; Beebe, Stephen J.; Buescher, E. Stephen Bioelectromagnetics, Vol. 22, Issue 6 https://doi.org/10.1002/bem.71	journal	January 2001
Electromechanical coupling mechanisms at a plasma–liquid interface Dickenson, A.; Walsh, J. L.; Hasan, M. I. Journal of Applied Physics, Vol. 129, Issue 21 https://doi.org/10.1063/5.0045088	journal	June 2021
Nonenzymatic post-translational modifications in peptides by cold plasma-derived reactive oxygen and nitrogen species Wenske, Sebastian; Lackmann, Jan-Wilm; Bekeschus, Sander Biointerphases, Vol. 15, Issue 6 https://doi.org/10.1116/6.0000529	journal	November 2020
Assay based on electrical impedance spectroscopy to discriminate between normal and cancerous mammalian cells Giana, Fabián Eduardo; Bonetto, Fabián José; Bellotti, Mariela Inés Physical Review E, Vol. 97, Issue 3 https://doi.org/10.1103/PhysRevE.97.032410	journal	March 2018
Expansion of surface barrier discharge scrutinized Lindner, M.; Pipa, A. V.; Brandenburg, R. Plasma Sources Science and Technology, Vol. 31, Issue 10 https://doi.org/10.1088/1361-6595/ac95bf	journal	October 2022
Interaction between a Liquid Surface and an Impinging Gas Jet Barron, Miguel A.; Medina, Dulce Y.; Reyes, Joan World Journal of Engineering and Technology, Vol. 09, Issue 04 https://doi.org/10.4236/wjet.2021.94055	journal	January 2021
Atmospheric plasma generates oxygen atoms as oxidizing species in aqueous solutions Hefny, Mohamed Mokhtar; Pattyn, Cedric; Lukes, Petr Journal of Physics D: Applied Physics, Vol. 49, Issue 40 https://doi.org/10.1088/0022-3727/49/40/404002	journal	September 2016
The Equivalent Circuit Approach for the Electrical Diagnostics of Dielectric Barrier Discharges: The Classical Theory and Recent Developments Pipa, Andrei; Brandenburg, Ronny Atoms, Vol. 7, Issue 1 https://doi.org/10.3390/atoms7010014	journal	January 2019
Dielectric measurement of cell death Patel, Pareshkumar; Markx, Gerard H. Enzyme and Microbial Technology, Vol. 43, Issue 7 https://doi.org/10.1016/j.enzmictec.2008.09.005	journal	December 2008
Combining experimental and modelling approaches to study the sources of reactive species induced in water by the COST RF plasma jet Gorbanev, Y.; Verlackt, C. C. W.; Tinck, S. Physical Chemistry Chemical Physics, Vol. 20, Issue 4 https://doi.org/10.1039/C7CP07616A	journal	January 2018
Electric potential developed by single-pulse needle-water discharge Okumura, Takamasa; Zhou, Chaoyi; Kubo, Eijiro Applied Physics Express, Vol. 11, Issue 1 https://doi.org/10.7567/APEX.11.016201	journal	December 2017
Evidence, origin and impact of liquid flows in plasma medicine in vitro treatments with APPJs Stancampiano, Augusto; Bocanegra, Pablo Escot; Dozias, Sébastien Plasma Sources Science and Technology, Vol. 30, Issue 1 https://doi.org/10.1088/1361-6595/abcc50	journal	January 2021
Characterization of plasma-induced cell membrane permeabilization: focus on OH radical distribution Sasaki, Shota; Honda, Ryosuke; Hokari, Yutaro Journal of Physics D: Applied Physics, Vol. 49, Issue 33 https://doi.org/10.1088/0022-3727/49/33/334002	journal	July 2016
Non-thermal plasma induces immunogenic cell deathin vivoin murine CT26 colorectal tumors Lin, Abraham G.; Xiang, Bo; Merlino, Dante J. OncoImmunology, Vol. 7, Issue 9 https://doi.org/10.1080/2162402X.2018.1484978	journal	July 2018
Plasma–liquid interactions: a review and roadmap Bruggeman, P. J.; Kushner, M. J.; Locke, B. R. Plasma Sources Science and Technology, Vol. 25, Issue 5 https://doi.org/10.1088/0963-0252/25/5/053002	journal	September 2016
Cell Electropermeabilisation Enhancement by Non-Thermal-Plasma-Treated PBS Chung, Thai-Hoa; Stancampiano, Augusto; Sklias, Kyriakos Cancers, Vol. 12, Issue 1 https://doi.org/10.3390/cancers12010219	journal	January 2020
From the basic science of biological effects of ultrashort electrical pulses to medical therapies Schoenbach, Karl H. Bioelectromagnetics, Vol. 39, Issue 4 https://doi.org/10.1002/bem.22117	journal	March 2018
VDAC, a multi-functional mitochondrial protein regulating cell life and death Shoshan-Barmatz, Varda; De Pinto, Vito; Zweckstetter, Markus Molecular Aspects of Medicine, Vol. 31, Issue 3 https://doi.org/10.1016/j.mam.2010.03.002	journal	June 2010
Peroxynitrite rapidly permeates phospholipid membranes Marla, S. S.; Lee, J.; Groves, J. T. Proceedings of the National Academy of Sciences, Vol. 94, Issue 26 https://doi.org/10.1073/pnas.94.26.14243	journal	December 1997
Non-touching plasma–liquid interaction – where is aqueous nitric oxide generated? Jablonowski, Helena; Schmidt-Bleker, Ansgar; Weltmann, Klaus-Dieter Physical Chemistry Chemical Physics, Vol. 20, Issue 39 https://doi.org/10.1039/C8CP02412J	journal	January 2018
Plasma Medicine: A Field of Applied Redox Biology Von Woedtke, Thomas; Schmidt, Anke; Bekeschus, Sander In Vivo, Vol. 33, Issue 4 https://doi.org/10.21873/invivo.11570	journal	January 2019
Study of an AC dielectric barrier single micro-discharge filament over a water film Vanraes, Patrick; Nikiforov, Anton; Bogaerts, Annemie Scientific Reports, Vol. 8, Issue 1 https://doi.org/10.1038/s41598-018-29189-w	journal	July 2018
Reactive Oxygen Species in Macrophages: Sources and Targets Canton, Marcella; Sánchez-Rodríguez, Ricardo; Spera, Iolanda Frontiers in Immunology, Vol. 12 https://doi.org/10.3389/fimmu.2021.734229	journal	September 2021
Estimation of H₂O₂ gradients across biomembranes Antunes, Fernando; Cadenas, Enrique FEBS Letters, Vol. 475, Issue 2 https://doi.org/10.1016/S0014-5793(00)01638-0	journal	June 2000
Differential Effect of Non-Thermal Plasma RONS on Two Human Leukemic Cell Populations Mohamed, Hager; Gebski, Eric; Reyes, Rufranshell Cancers, Vol. 13, Issue 10 https://doi.org/10.3390/cancers13102437	journal	May 2021
Oxidized phosphatidylcholines in membrane‐level cellular signaling: from biophysics to physiology and molecular pathology Volinsky, Roman; Kinnunen, Paavo K. J. The FEBS Journal, Vol. 280, Issue 12 https://doi.org/10.1111/febs.12247	journal	April 2013
Relation of electric conditions between a source of Ar plasma jet and a substrate with a configuration of a plasma sheet on a target Akishev, Yu S.; Balakirev, A. A.; Karalnik, V. B. Journal of Physics: Conference Series, Vol. 1328, Issue 1 https://doi.org/10.1088/1742-6596/1328/1/012060	journal	October 2019
Following O and OH in He/O ₂ and He/H ₂ O gas mixtures—from the gas phase through the liquid phase to modifications on a biological sample Stapelmann, Katharina; Myers, Brayden; Quesada, Maria Herrera Journal of Physics D: Applied Physics, Vol. 54, Issue 43 https://doi.org/10.1088/1361-6463/ac18ec	journal	August 2021
Nitric Oxide and Peroxynitrite in Health and Disease Pacher, Pál; Beckman, Joseph S.; Liaudet, Lucas Physiological Reviews, Vol. 87, Issue 1 https://doi.org/10.1152/physrev.00029.2006	journal	January 2007
Chemical fingerprints of cold physical plasmas – an experimental and computational study using cysteine as tracer compound Lackmann, J. -W.; Wende, K.; Verlackt, C. Scientific Reports, Vol. 8, Issue 1 https://doi.org/10.1038/s41598-018-25937-0	journal	May 2018
FTIR spectroscopy of cysteine as a ready-to-use method for the investigation of plasma-induced chemical modifications of macromolecules Kogelheide, Friederike; Kartaschew, Konstantin; Strack, Martin Journal of Physics D: Applied Physics, Vol. 49, Issue 8 https://doi.org/10.1088/0022-3727/49/8/084004	journal	January 2016
Cold atmospheric plasma-induced oxidative stress and ensuing immunological response – a Neo-Vista in immunotherapy P. R., Sreedevi; K., Suresh; S., Yugeswaran Free Radical Research, Vol. 56, Issue 7-8 https://doi.org/10.1080/10715762.2022.2139691	journal	August 2022
Concepts and characteristics of the ‘COST Reference Microplasma Jet’ Golda, J.; Held, J.; Redeker, B. Journal of Physics D: Applied Physics, Vol. 49, Issue 8 https://doi.org/10.1088/0022-3727/49/8/084003	journal	January 2016
A novel approach for using dielectric spectroscopy to predict viable cell volume (VCV) in early process development Downey, Brandon J.; Graham, Lisa J.; Breit, Jeffrey F. Biotechnology Progress, Vol. 30, Issue 2 https://doi.org/10.1002/btpr.1845	journal	January 2014
Using Plasma to Treat Chronic Foot Ulcer Infections Terabe, Yuta; Kaneko, Nobuhito; Nakabayashi, Keisuke International Journal of Surgical Wound Care, Vol. 3, Issue 2, p. 33-36 https://doi.org/10.36748/ijswc.3.2_33	journal	January 2022
Biodielectrics Weaver, J. C.; Schoenbach, K. H. IEEE Transactions on Dielectrics and Electrical Insulation, Vol. 10, Issue 5 https://doi.org/10.1109/TDEI.2003.1237322	journal	October 2003
The effect of liquid target on a nonthermal plasma jet—imaging, electric fields, visualization of gas flow and optical emission spectroscopy Kovačević, Vesna V.; Sretenović, Goran B.; Slikboer, Elmar Journal of Physics D: Applied Physics, Vol. 51, Issue 6 https://doi.org/10.1088/1361-6463/aaa288	journal	January 2018
GSH Modification as a Marker for Plasma Source and Biological Response Comparison to Plasma Treatment Ranieri, Pietro; Mohamed, Hager; Myers, Brayden Applied Sciences, Vol. 10, Issue 6 https://doi.org/10.3390/app10062025	journal	March 2020
Determination of membrane capacitance and cytoplasm conductivity by simultaneous electrorotation Kawai, Shikiho; Suzuki, Masato; Arimoto, Satoshi The Analyst, Vol. 145, Issue 12 https://doi.org/10.1039/D0AN00100G	journal	January 2020
The interaction of an atmospheric pressure plasma jet with liquid water: dimple dynamics and its impact on crystal violet decomposition Kondeti, V. S. Santosh K.; Bruggeman, Peter J. Journal of Physics D: Applied Physics, Vol. 54, Issue 4 https://doi.org/10.1088/1361-6463/abbeb5	journal	November 2020
The anti-glioblastoma effect of cold atmospheric plasma treatment: physical pathway v.s. chemical pathway Yan, Dayun; Wang, Qihui; Malyavko, Alisa Scientific Reports, Vol. 10, Issue 1 https://doi.org/10.1038/s41598-020-68585-z	journal	July 2020
Mass Accommodation and Chemical Reactions at Gas−Liquid Interfaces Davidovits, Paul; Kolb, Charles E.; Williams, Leah R. Chemical Reviews, Vol. 106, Issue 4 https://doi.org/10.1021/cr040366k	journal	April 2006
Plasmas for Treating Cancer: Opportunities for Adaptive and Self-Adaptive Approaches Keidar, Michael; Yan, Dayun; Beilis, Isak I. Trends in Biotechnology, Vol. 36, Issue 6 https://doi.org/10.1016/j.tibtech.2017.06.013	journal	June 2018
Hydrogen peroxide permeability of cellular membranes in insulin-producing cells Laporte, Anna; Lortz, Stephan; Schaal, Christina Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1862, Issue 2 https://doi.org/10.1016/j.bbamem.2019.183096	journal	February 2020
Decomposition and oxidation of methionine and tryptophan following irradiation with a nonequilibrium plasma jet and applications for killing cancer cells Uchida, Giichiro; Mino, Yusuke; Suzuki, Tensho Scientific Reports, Vol. 9, Issue 1 https://doi.org/10.1038/s41598-019-42959-4	journal	April 2019
Non-thermal plasma modulates cellular markers associated with immunogenicity in a model of latent HIV-1 infection Mohamed, Hager; Clemen, Ramona; Freund, Eric PLOS ONE, Vol. 16, Issue 3 https://doi.org/10.1371/journal.pone.0247125	journal	March 2021
S-Nitrosylation in Regulation of Inflammation and Cell Damage Dasgupta, Subhajit; Gomez, Jenny- Jaramillo; Singh, Inderjit Current Drug Targets, Vol. 19, Issue 15 https://doi.org/10.2174/1389450119666180213094747	journal	October 2018
Hydrogen peroxide – production, fate and role in redox signaling of tumor cells Lennicke, Claudia; Rahn, Jette; Lichtenfels, Rudolf Cell Communication and Signaling, Vol. 13, Issue 1 https://doi.org/10.1186/s12964-015-0118-6	journal	September 2015
Intermolecular Peroxyl Radical Reactions during Autoxidation of Hydroxy and Hydroperoxy Arachidonic Acids Generate a Novel Series of Epoxidized Products Schneider, Claus; Boeglin, William E.; Yin, Huiyong Chemical Research in Toxicology, Vol. 21, Issue 4 https://doi.org/10.1021/tx700357u	journal	March 2008
Investigation of plasma dynamics and spatially varying O and OH concentrations in atmospheric pressure plasma jets impinging on glass, water and metal substrates Yue, Yuanfu; Pei, Xuekai; Gidon, Dogan Plasma Sources Science and Technology, Vol. 27, Issue 6 https://doi.org/10.1088/1361-6595/aac618	journal	June 2018
Cold Atmospheric Plasma Treatment Induces Anti-Proliferative Effects in Prostate Cancer Cells by Redox and Apoptotic Signaling Pathways Weiss, Martin; Gümbel, Denis; Hanschmann, Eva-Maria PLOS ONE, Vol. 10, Issue 7 https://doi.org/10.1371/journal.pone.0130350	journal	July 2015
Determination of Dielectric Properties of Cells using AC Electrokinetic-based Microfluidic Platform: A Review of Recent Advances Liang, Wenfeng; Yang, Xieliu; Wang, Junhai Micromachines, Vol. 11, Issue 5 https://doi.org/10.3390/mi11050513	journal	May 2020
The solvation of electrons by an atmospheric-pressure plasma Rumbach, Paul; Bartels, David M.; Sankaran, R. Mohan Nature Communications, Vol. 6, Issue 1 https://doi.org/10.1038/ncomms8248	journal	June 2015
Low-Temperature Plasma for Biology, Hygiene, and Medicine: Perspective and Roadmap Laroussi, Mounir; Bekeschus, Sander; Keidar, Michael IEEE Transactions on Radiation and Plasma Medical Sciences, Vol. 6, Issue 2 https://doi.org/10.1109/TRPMS.2021.3135118	journal	February 2022
Membrane transport of hydrogen peroxide Bienert, Gerd P.; Schjoerring, Jan K.; Jahn, Thomas P. Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1758, Issue 8 https://doi.org/10.1016/j.bbamem.2006.02.015	journal	August 2006
Helium atmospheric pressure plasma jets touching dielectric and metal surfaces Norberg, Seth A.; Johnsen, Eric; Kushner, Mark J. Journal of Applied Physics, Vol. 118, Issue 1 https://doi.org/10.1063/1.4923345	journal	July 2015
Air plasma treatment of liquid covered tissue: long timescale chemistry Lietz, Amanda M.; Kushner, Mark J. Journal of Physics D: Applied Physics, Vol. 49, Issue 42 https://doi.org/10.1088/0022-3727/49/42/425204	journal	September 2016
Hydroperoxide metabolism in mammalian organs. Chance, B.; Sies, H.; Boveris, A. Physiological Reviews, Vol. 59, Issue 3 https://doi.org/10.1152/physrev.1979.59.3.527	journal	July 1979
What is the concentration of hydrogen peroxide in blood and plasma? Forman, Henry Jay; Bernardo, Angelito; Davies, Kelvin J. A. Archives of Biochemistry and Biophysics, Vol. 603 https://doi.org/10.1016/j.abb.2016.05.005	journal	August 2016
Deciphering cell–cell interactions and communication from gene expression Armingol, Erick; Officer, Adam; Harismendy, Olivier Nature Reviews Genetics, Vol. 22, Issue 2 https://doi.org/10.1038/s41576-020-00292-x	journal	November 2020
Redox Redux: Revisiting PTPs and the Control of Cell Signaling Tonks, Nicholas K. Cell, Vol. 121, Issue 5 https://doi.org/10.1016/j.cell.2005.05.016	journal	June 2005
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics Szabó, Csaba; Ischiropoulos, Harry; Radi, Rafael Nature Reviews Drug Discovery, Vol. 6, Issue 8 https://doi.org/10.1038/nrd2222	journal	August 2007
Synergistic effect of electrical and chemical factors on endocytosis in micro-discharge plasma gene transfection Jinno, M.; Ikeda, Y.; Motomura, H. Plasma Sources Science and Technology, Vol. 26, Issue 6 https://doi.org/10.1088/1361-6595/aa70de	journal	May 2017
Evaluation of Cellular and Systemic Toxicity of Dielectric Barrier Discharge Plasma-Treated N-Acetylcysteine as Potential Antimicrobial Catheter Lock Solution Ercan, Utku K.; Yost, Adam D.; Wasko, Kimberly Plasma, Vol. 4, Issue 4 https://doi.org/10.3390/plasma4040036	journal	October 2021
Understanding Cellular Redox Homeostasis: A Challenge for Precision Medicine Tretter, Verena; Hochreiter, Beatrix; Zach, Marie Louise International Journal of Molecular Sciences, Vol. 23, Issue 1 https://doi.org/10.3390/ijms23010106	journal	December 2021
Nanosecond-Pulsed Dielectric Barrier Discharge–Induced Antitumor Effects Propagate through Depth of Tissue via Intracellular Signaling Ranieri, P.; Shrivastav, R.; Wang, M. Plasma Medicine, Vol. 7, Issue 3 https://doi.org/10.1615/PlasmaMed.2017019883	journal	January 2017
Chemical Changes in Nonthermal Plasma-Treated N-Acetylcysteine (NAC) Solution and TheirContribution to Bacterial Inactivation Ercan, Utku K.; Smith, Josh; Ji, Hai-Feng Scientific Reports, Vol. 6, Issue 1 https://doi.org/10.1038/srep20365	journal	February 2016

Similar Records

TH-E-BRD-01: Innovation in (gold) Nanoparticle-Enhanced Therapy

Journal Article · 2014 · Medical Physics · OSTI ID:22412401

Krishnan, S; Chithrani, B; Berbeco, R

Electron generation and multiplication at the initial stage of nanosecond breakdown in water

Journal Article · 2021 · Journal of Applied Physics · OSTI ID:1818980

Zhang, Xuewei; Shneider, Mikhail N.

Advances in targeted proteomics and applications to biomedical research

Journal Article · 2016 · Proteomics · OSTI ID:1340855

Shi, Tujin; Song, Ehwang; Nie, Song; +4 more

Related Subjects

70 PLASMA PHYSICS AND FUSION TECHNOLOGY
Electrical properties and parameters
Dielectric properties
Interfaces
Plasma sources
Free radicals
Lipids
Proteins
Cell cultures
Cell membranes

Title: Plasma–liquid interactions in the presence of organic matter—A perspective

Citation Formats

References (137)

Similar Records

Related Subjects