Reinforced double-threaded slide-ring networks for accelerated hydrogel discovery and 3D printing

Tang, Miao; Zheng, Dan; Samanta, Jayanta; Tsai, Esther H. R.; Qiu, Huibin; Read, Jacquelyne A.; Ke, Chenfeng

doi:10.1016/j.chempr.2023.07.020

Title: Reinforced double-threaded slide-ring networks for accelerated hydrogel discovery and 3D printing

Journal Article · 22 August 2023 · Chem

DOI: https://doi.org/10.1016/j.chempr.2023.07.020 · OSTI ID:2352187

Tang, Miao ^[1]; Zheng, Dan ^[1]; Samanta, Jayanta ^[1];

^[2]; Qiu, Huibin ^[3]; Read, Jacquelyne A. ^[1];

^[1]

Dartmouth College, Hanover, NH (United States)
Brookhaven National Laboratory (BNL), Upton, NY (United States). Center for Functional Nanomaterials (CFN)
Shanghai Jiao Tong Univ. (China)

Traditionally, slide-ring gels are stretchable but soft as a result of an elasticity-stretchability trade-off. Herein, we introduce a new approach to breaking this trade-off and creating reinforced slide-ring networks with mobile crosslinkers. Our approach involves the construction of a polyethylene glycol double-threaded γ-cyclodextrin-based pro-slide-ring crosslinker that serves as a modular component for 3D printing and copolymerization. The resulting crystalline-domain-reinforced slide-ring hydrogels, or CrysDoS-gels, exhibit both high elasticity and high stretchability. The modular synthesis allows for high-throughput synthesis of CrysDoS-gels, generating a large amount of data for structure-property analysis. Here, by employing data science techniques, such as machine learning and linear regression, not only were we able to identify which chemical components influence the mechanical properties of CrysDoS-gels, but this analysis also aided in the discovery of better-performing CrysDoS-gels. Finally, we demonstrate the potential application of the newly discovered CrysDoS-gels as sensing devices by 3D printing them as stress sensors with high sensitivity and a broad detection range.

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Research Organization:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Organization:: National Science Foundation (NSF); USDOE Office of Science (SC), Basic Energy Sciences (BES). Scientific User Facilities (SUF)

Grant/Contract Number:: SC0012704; SC0022267

OSTI ID:: 2352187

Report Number(s):: BNL--225613-2024-JAAM

Journal Information:: Chem, Journal Name: Chem Journal Issue: 12 Vol. 9; ISSN 2451-9294

Publisher:: Cell PressCopyright Statement

Country of Publication:: United States

Language:: English

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Title: Reinforced double-threaded slide-ring networks for accelerated hydrogel discovery and 3D printing

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