Replacing a Cysteine Ligand by Selenocysteine in a [NiFe]-Hydrogenase Unlocks Hydrogen Production Activity and Addresses the Role of Concerted Proton-Coupled Electron Transfer in Electrocatalytic Reversibility

Evans, Rhiannon M.; Krahn, Natalie; Weiss, Joshua; Vincent, Kylie A.; Söll, Dieter; Armstrong, Fraser A.

doi:10.1021/jacs.4c03489

Title: Replacing a Cysteine Ligand by Selenocysteine in a [NiFe]-Hydrogenase Unlocks Hydrogen Production Activity and Addresses the Role of Concerted Proton-Coupled Electron Transfer in Electrocatalytic Reversibility

Journal Article · 14 May 2024 · Journal of the American Chemical Society

DOI: https://doi.org/10.1021/jacs.4c03489 · OSTI ID:2350845

Evans, Rhiannon M. ^[1];

^[2]; Weiss, Joshua ^[2];

^[1];

^[3];

^[1]

Department of Chemistry, University of Oxford, Oxford OX1 3TA, United Kingdom
Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511, United States, Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States

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Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: FG02-98ER20311

OSTI ID:: 2350845

Alternate ID(s):: OSTI ID: 2394610

Journal Information:: Journal of the American Chemical Society, Journal Name: Journal of the American Chemical Society Journal Issue: 25 Vol. 146; ISSN 0002-7863

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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