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Title: Recent developments in enzymatic and microbial biosynthesis of flavor and fragrance molecules

Journal Article · · Journal of Biotechnology

Not Available

Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
Grant/Contract Number:
SC0021166
OSTI ID:
2345818
Journal Information:
Journal of Biotechnology, Journal Name: Journal of Biotechnology Journal Issue: C Vol. 389; ISSN 0168-1656
Publisher:
ElsevierCopyright Statement
Country of Publication:
Netherlands
Language:
English

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Metabolic engineering Saccharomyces cerevisiae for de novo production of the sesquiterpenoid (+)-nootkatone journal February 2020
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Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase journal August 2017
Microbial production of methyl anthranilate, a grape flavor compound journal May 2019
Efficient utilization of carbon to produce aromatic valencene in Saccharomyces cerevisiae using mannitol as the substrate journal January 2022
Biosynthesis of pinene from glucose using metabolically-engineered Corynebacterium glutamicum journal June 2014
Therapeutic Potential of α- and β-Pinene: A Miracle Gift of Nature journal November 2019
Utilization of a styrene-derived pathway for 2-phenylethanol production in budding yeast journal March 2021
Metabolic engineering of Synechocystis sp. PCC 6803 for the photoproduction of the sesquiterpene valencene journal December 2021
Efficient Biosynthesis of R-(−)-Linalool through Adjusting the Expression Strategy and Increasing GPP Supply in Escherichia coli journal July 2020
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Thermodynamics contributes to high limonene productivity in cyanobacteria journal June 2022
CRISPR-mediated multigene integration enables Shikimate pathway refactoring for enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus journal January 2021
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Ustilago maydis Serves as a Novel Production Host for the Synthesis of Plant and Fungal Sesquiterpenoids journal July 2020
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Stepwise engineering of Saccharomyces cerevisiae to produce (+)-valencene and its related sesquiterpenes journal January 2019
Techno-economic assessment of microbial limonene production journal March 2020
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Metabolic engineering of Deinococcus radiodurans for pinene production from glycerol journal September 2021
Enhanced limonene production in a fast-growing cyanobacterium through combinatorial metabolic engineering journal June 2021
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A Review of the Potential Use of Pinene and Linalool as Terpene-Based Medicines for Brain Health: Discovering Novel Therapeutics in the Flavours and Fragrances of Cannabis journal August 2021
Metabolic engineering of Saccharomyces cerevisiae for linalool production journal November 2015
Synthesis of the character impact compound raspberry ketone and additional flavoring phenylbutanoids of biotechnological interest with Corynebacterium glutamicum journal April 2020
Production, Function, and Applications of the Sesquiterpenes Valencene and Nootkatone: a Comprehensive Review journal December 2022
Zygosaccharomyces rouxii, an Aromatic Yeast Isolated From Chili Sauce, Is Able to Biosynthesize 2-Phenylethanol via the Shikimate or Ehrlich Pathways journal October 2020
Identification and Characterization of the Linalool/Nerolidol Synthase from Streptomyces clavuligerus journal September 2011
Microbial production of butyl butyrate, a flavor and fragrance compound journal January 2019
Enhancement of 2-phenylethanol production by a wild-type Wickerhamomyces anomalus strain isolated from rice wine journal December 2020
Piperonal synthase from black pepper (Piper nigrum) synthesizes a phenolic aroma compound, piperonal, as a CoA-independent catalysis journal March 2022
Engineering yeast for bio-production of food ingredients journal November 2022
An ADH toolbox for raspberry ketone production from natural resources via a biocatalytic cascade journal May 2021
Vanillin biosynthetic pathways in plants journal March 2017
Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli journal June 2015
Improved linalool production in Saccharomyces cerevisiae by combining directed evolution of linalool synthase and overexpression of the complete mevalonate pathway journal September 2020
Alcohol acyltransferases for the biosynthesis of esters journal June 2023
Microbial Cell Factories for the Production of Terpenoid Flavor and Fragrance Compounds journal April 2017
Advances in the synthesis and applications of raspberry ketone: A review journal September 2021
Efficient synthesis of 2-phenylethanol from L-phenylalanine by engineered Bacillus licheniformis using molasses as carbon source journal July 2020
Combinatorial gene inactivation of aldehyde dehydrogenases mitigates aldehyde oxidation catalyzed by E. coli resting cells journal May 2023
Whole-Cell Production of Patchouli Oil Sesquiterpenes in Escherichia coli: Metabolic Engineering and Fermentation Optimization in Solid–Liquid Phase Partitioning Cultivation journal December 2020
Construction of a Microbial Consortium for the De Novo Synthesis of Butyl Butyrate from Renewable Resources journal February 2023
Engineering Escherichia coli for production of geraniol by systematic synthetic biology approaches and laboratory-evolved fusion tags journal July 2021
Directing vanillin production from ferulic acid by increased acetyl‐CoA consumption in recombinant Escherichia coli journal August 2008
Development of a Vanillate Biosensor for the Vanillin Biosynthesis Pathway in E. coli journal August 2019
Metabolic engineering of Escherichia coli for the biosynthesis of alpha-pinene journal January 2013
Metabolic engineering of Clostridium acetobutylicum for the production of butyl butyrate journal August 2018
Recent advances in the microbial and enzymatic production of aroma compounds journal February 2021
Menthol: A refreshing look at this ancient compound journal November 2007
Improving monoterpene geraniol production through geranyl diphosphate synthesis regulation in Saccharomyces cerevisiae journal February 2016
Improvement of 2-phenylethanol production in Saccharomyces cerevisiae by evolutionary and rational metabolic engineering journal October 2021
De Novo Biosynthesis of Methyl Cinnamate in Engineered Escherichia coli journal June 2022
Improved pinene production in a recombinant yeast by fusion linker optimization and chaperon coexpression journal August 2021
Microbial production of butyl butyrate: from single strain to cognate consortium journal June 2021
Microbial production of scent and flavor compounds journal February 2016
Metabolic engineering of oleaginous yeast Yarrowia lipolytica for limonene overproduction journal October 2016
Genome engineering allows selective conversions of terephthalaldehyde to multiple valorized products in bacterial cells journal August 2023
Heterologous production of raspberry ketone in the wine yeast Saccharomyces cerevisiae via pathway engineering and synthetic enzyme fusion journal March 2016
High production of valencene in Saccharomyces cerevisiae through metabolic engineering journal November 2019
Biosynthesis of pinene in purple non-sulfur photosynthetic bacteria journal May 2021
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Generation of Flavors and Fragrances Through Biotransformation and De Novo Synthesis journal September 2018
Towards synthesis of monoterpenes and derivatives using synthetic biology journal October 2016
Transcriptional Tuning of Mevalonate Pathway Enzymes to Identify the Impact on Limonene Production in Escherichia coli journal May 2022
Enhanced acetoin production by Serratia marcescens H32 with expression of a water-forming NADH oxidase journal September 2012
Systematic metabolic engineering of Escherichia coli for the enhanced production of cinnamaldehyde journal March 2023
Method for the enzymatic preparation of flavours rich in C6-C10 aldehydes book January 2006
Engineering of Clostridium tyrobutyricum for butyric acid and butyl butyrate production from cassava starch journal January 2024
Phenylpropanoid Biosynthesis journal January 2010
Engineering an Alcohol-Forming Fatty Acyl-CoA Reductase for Aldehyde and Hydrocarbon Biosynthesis in Saccharomyces cerevisiae journal October 2020
Connecting central carbon and aromatic amino acid metabolisms to improve de novo 2-phenylethanol production in Saccharomyces cerevisiae journal December 2019
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Construction and Optimization of Nonclassical Isoprenoid Biosynthetic Pathways in Yeast Peroxisomes for (+)-Valencene Production journal July 2023
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Sensing, Uptake and Catabolism of L-Phenylalanine During 2-Phenylethanol Biosynthesis via the Ehrlich Pathway in Saccharomyces cerevisiae journal February 2021
Plant-Derived Terpenes: A Feedstock for Specialty Biofuels journal March 2017
Metabolic engineering of Escherichia coli for the production of cinnamaldehyde journal January 2016
One‐Pot Production of Natural 2‐Phenylethanol from L‐Phenylalanine via Cascade Biotransformations journal January 2019
Engineered mitochondrial production of monoterpenes in Saccharomyces cerevisiae journal September 2019
Production of the Fragrance Geraniol in Peroxisomes of a Product-Tolerant Baker’s Yeast journal September 2020
Production of plant sesquiterpenes inSaccharomyces cerevisiae: Effect ofERG9 repression on sesquiterpene biosynthesis journal January 2007
Isobutyraldehyde production from Escherichia coli by removing aldehyde reductase activity journal January 2012
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids journal June 2003
Proteome reallocation enables the selective de novo biosynthesis of non-linear, branched-chain acetate esters journal September 2022
Enzymatic reactions towards aldehydes: An overview journal April 2023
Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture journal March 2016
Recent Developments in the Synthesis of the Flavors and Fragrances of Terpenoid Origin book April 2015
Combining metabolite doping and metabolic engineering to improve 2-phenylethanol production by engineered cyanobacteria journal September 2022
Enhancing the Production of Pinene in Escherichia coli by Using a Combination of Shotgun, Product-Tolerance and I-SceI Cleavage Systems journal October 2022
Engineered Rhodobacter capsulatus as a Phototrophic Platform Organism for the Synthesis of Plant Sesquiterpenoids journal September 2019
Genomic, transcriptomic, and metabolic characterization of 2-Phenylethanol-resistant Saccharomyces cerevisiae obtained by evolutionary engineering journal April 2023
Ethyl acetate production by the elusive alcohol acetyltransferase from yeast journal May 2017
Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production journal September 2013
Combinatorial engineering of Saccharomyces cerevisiae for improving limonene production journal December 2021