Native Mass Spectrometry Dissects the Structural Dynamics of an Allosteric Heterodimer of SARS-CoV-2 Nonstructural Proteins

Thibert, Stephanie M.; Reid, Deseree J.; Wilson, Jesse W.; Varikoti, Rohith; Maltseva, Natalia; Schultz, Katherine J.; Kruel, Agustin; Babnigg, Gyorgy; Joachimiak, Andrzej; Kumar, Neeraj; Zhou, Mowei

doi:10.1021/jasms.3c00453

Title: Native Mass Spectrometry Dissects the Structural Dynamics of an Allosteric Heterodimer of SARS-CoV-2 Nonstructural Proteins

Journal Article · 26 March 2024 · Journal of the American Society for Mass Spectrometry

DOI: https://doi.org/10.1021/jasms.3c00453 · OSTI ID:2329351

Thibert, Stephanie M. ^[1]; Reid, Deseree J. ^[2];

^[1]; Varikoti, Rohith ^[3]; Maltseva, Natalia ^[4]; Schultz, Katherine J. ^[3];

^[3];

^[5]; Joachimiak, Andrzej ^[4];

^[3];

^[1]

Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99354, United States
Chemical and Biological Signature Sciences, Pacific Northwest National Laboratory, Richland, Washington 99354, United States
Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States
Center for Structural Biology of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, Illinois 60637, United States, Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, Illinois 60439, United States
Center for Structural Biology of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, Illinois 60637, United States, Biosciences Division, Argonne National Laboratory, Argonne, Illinois 60439, United States

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Sponsoring Organization:: USDOE

OSTI ID:: 2329351

Alternate ID(s):: OSTI ID: 2345198; OSTI ID: 2566109

Journal Information:: Journal of the American Society for Mass Spectrometry, Journal Name: Journal of the American Society for Mass Spectrometry Journal Issue: 5 Vol. 35; ISSN 1044-0305

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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