Title: Qualitative and quantitative analysis of glutathione and related impurities in pharmaceuticals by qNMR

Journal Article · · Journal of Pharmaceutical and Biomedical Analysis
; ; ; ; ; ;

Not Available

Research Organization:
Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE; USDOE Office of Science (SC)
Grant/Contract Number:
SC0014664
OSTI ID:
2311906
Journal Information:
Journal of Pharmaceutical and Biomedical Analysis, Journal Name: Journal of Pharmaceutical and Biomedical Analysis Journal Issue: C Vol. 242; ISSN 0731-7085
Publisher:
ElsevierCopyright Statement
Country of Publication:
Country unknown/Code not available
Language:
English

References (20)

Capillary electrophoresis method for determination of related substances in glutathione reduced drug substance journal March 2003
Pharmaceutical Compounding: a History, Regulatory Overview, and Systematic Review of Compounding Errors journal November 2020
Analytical methods to investigate glutathione and related compounds in biological and pathological processes journal December 2002
Glutathione as a Marker for Human Disease book August 2018
Distinguishing between compounding facilities and the development of the 503B bulk drug substance list journal January 2021
Determination of glutathione and glutathione disulfide in biological samples: An in-depth review journal October 2009
Pharmaceutical impurities and degradation products: Uses and applications of NMR techniques journal December 2014
Pharmaceutical analysis by NMR can accommodate strict impurity thresholds: The case of choline journal May 2022
Seven cases of probable endotoxin poisoning related to contaminated glutathione infusions journal April 2018
Importance of Purity Evaluation and the Potential of Quantitative 1 H NMR as a Purity Assay: Miniperspective journal October 2014
Kinetics and equilibria of thiol/disulfide interchange reactions of selected biological thiols and related molecules with oxidized glutathione journal January 1992
Studies on the reaction of glutathione and formaldehyde using NMR journal January 2010
Toward Better-Quality Compounded Drugs — An Update from the FDA journal December 2017
Conformation of reduced glutathione in aqueous solution by 1H and 13C n.m.r. journal May 1987
Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study journal August 2017
A clinical trial of glutathione supplementation in autism spectrum disorders journal January 2011
The Drug Quality and Security Act journal July 2014
Glutathione: Pharmacological aspects and implications for clinical use in non-alcoholic fatty liver disease journal March 2023
Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation journal November 2022
Randomized Clinical Trial of How Long-Term Glutathione Supplementation Offers Protection from Oxidative Damage and Improves HbA1c in Elderly Type 2 Diabetic Patients journal May 2022

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Related Subjects

Chemistry
Pharmacology & Pharmacy