From a hunger-regulating hormone to an antimicrobial peptide: gastrointestinal derived circulating endocrine hormone-peptide YY exerts exocrine antimicrobial effects against selective gut microbiota

Xiao, Yuchen; Jin, Lingjing; Zhang, Chao

doi:10.1080/19490976.2024.2316927

Title: From a hunger-regulating hormone to an antimicrobial peptide: gastrointestinal derived circulating endocrine hormone-peptide YY exerts exocrine antimicrobial effects against selective gut microbiota

Journal Article · 13 February 2024 · Gut Microbes

DOI: https://doi.org/10.1080/19490976.2024.2316927 · OSTI ID:2305564

Xiao, Yuchen ^[1];

^[1];

^[1]

Fundamental Research Center, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai, China

Not Available

View Journal Article

Cite

Export

Save

Sponsoring Organization:: USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research

OSTI ID:: 2305564

Journal Information:: Gut Microbes, Journal Name: Gut Microbes Journal Issue: 1 Vol. 16; ISSN 1949-0976

Publisher:: Informa UK LimitedCopyright Statement

Country of Publication:: United States

Language:: English

References (25)

Regional epithelial cell diversity in the small intestine of pigs Wiarda, Jayne E.; Becker, Sage R.; Sivasankaran, Sathesh K. Journal of Animal Science, Vol. 101 https://doi.org/10.1093/jas/skac318	journal	October 2022
Peptide YY: A Paneth cell antimicrobial peptide that maintains Candida gut commensalism Pierre, Joseph F.; Peters, Brian M.; La Torre, Diana Science, Vol. 381, Issue 6657 https://doi.org/10.1126/science.abq3178	journal	August 2023
Antimicrobial Defense of the Intestine Mukherjee, Sohini; Hooper, Lora V. Immunity, Vol. 42, Issue 1 https://doi.org/10.1016/j.immuni.2014.12.028	journal	January 2015
Identification of antimicrobial peptides from the human gut microbiome using deep learning Ma, Yue; Guo, Zhengyan; Xia, Binbin Nature Biotechnology, Vol. 40, Issue 6 https://doi.org/10.1038/s41587-022-01226-0	journal	March 2022
Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut–brain axis Holzer, Peter; Reichmann, Florian; Farzi, Aitak Neuropeptides, Vol. 46, Issue 6 https://doi.org/10.1016/j.npep.2012.08.005	journal	December 2012
The Gut-Brain Axis, the Human Gut Microbiota and Their Integration in the Development of Obesity Bliss, Edward S.; Whiteside, Eliza Frontiers in Physiology, Vol. 9 https://doi.org/10.3389/fphys.2018.00900	journal	July 2018
Multifaceted involvements of Paneth cells in various diseases within intestine and systemically Cui, Chenbin; Wang, Xinru; Li, Lindeng Frontiers in Immunology, Vol. 14 https://doi.org/10.3389/fimmu.2023.1115552	journal	March 2023
The antimicrobial peptide Magainin-2 interacts with BamA impairing folding of E. coli membrane proteins Di Somma, Angela; Cané, Carolina; Moretta, Antonio Frontiers in Chemistry, Vol. 10 https://doi.org/10.3389/fchem.2022.1013788	journal	October 2022
Fungal microbiota dysbiosis in IBD Sokol, Harry; Leducq, Valentin; Aschard, Hugues Gut, Vol. 66, Issue 6 https://doi.org/10.1136/gutjnl-2015-310746	journal	February 2016
Paneth cells as a site of origin for intestinal inflammation Adolph, Timon E.; Tomczak, Michal F.; Niederreiter, Lukas Nature, Vol. 503, Issue 7475 https://doi.org/10.1038/nature12599	journal	October 2013
Adiponectin as a therapeutic target for diabetic foot ulcer Abdalla, Mona Mohamed Ibrahim; Mohanraj, Jaiprakash; Somanath, Sushela Devi World Journal of Diabetes, Vol. 14, Issue 6 https://doi.org/10.4239/wjd.v14.i6.758	journal	June 2023
Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice Hansen, Henrik H.; Grønlund, Rikke V.; Baader-Pagler, Tamara Scientific Reports, Vol. 11, Issue 1 https://doi.org/10.1038/s41598-021-87539-7	journal	April 2021
Spatiotemporal analysis of human intestinal development at single-cell resolution Fawkner-Corbett, David; Antanaviciute, Agne; Parikh, Kaushal Cell, Vol. 184, Issue 3 https://doi.org/10.1016/j.cell.2020.12.016	journal	February 2021
Anti-diabetics and antimicrobials: Harmony of mutual interplay Hegazy, Wael A. H.; Rajab, Azza A. H.; Abu Lila, Amr S. World Journal of Diabetes, Vol. 12, Issue 11 https://doi.org/10.4239/wjd.v12.i11.1832	journal	November 2021
Enterohormone therapy for short bowel syndrome Verbiest, Astrid; Wauters, Lucas; Vanuytsel, Tim Current Opinion in Endocrinology, Diabetes & Obesity, Vol. 29, Issue 2 https://doi.org/10.1097/MED.0000000000000710	journal	January 2022
Cell transcriptomic atlas of the non-human primate Macaca fascicularis Han, Lei; Wei, Xiaoyu; Liu, Chuanyu Nature, Vol. 604, Issue 7907 https://doi.org/10.1038/s41586-022-04587-3	journal	April 2022
Candida albicans Morphogenesis Programs Control the Balance between Gut Commensalism and Invasive Infection Witchley, Jessica N.; Penumetcha, Pallavi; Abon, Nina V. Cell Host & Microbe, Vol. 25, Issue 3 https://doi.org/10.1016/j.chom.2019.02.008	journal	March 2019
Melatonin inhibits Gram-negative pathogens by targeting citrate synthase He, Fang; Liu, Yuan; Li, Pan Science China Life Sciences, Vol. 65, Issue 7 https://doi.org/10.1007/s11427-021-2032-9	journal	January 2022
The Role of Neuropeptide Y and Peptide YY in the Development of Obesity via Gut-brain Axis Wu, Yi; He, Hengxun; Cheng, Zhibin Current Protein & Peptide Science, Vol. 20, Issue 7 https://doi.org/10.2174/1389203720666190125105401	journal	June 2019
Glicentin inhibits internalization of enteric bacteria by cultured INT-407 enterocytes Chiba, Masahiro; Sanada, Yutaka; Kawano, Shinya Pediatric Surgery International, Vol. 23, Issue 6 https://doi.org/10.1007/s00383-007-1895-9	journal	February 2007
Sitagliptin and Roux‐en‐Y gastric bypass modulate insulin secretion via regulation of intra‐islet PYY Guida, Claudia; McCulloch, Laura J.; Godazgar, Mahdieh Diabetes, Obesity and Metabolism, Vol. 20, Issue 3 https://doi.org/10.1111/dom.13113	journal	October 2017
Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease Wang, Shu-Ling; Shao, Bo-Zong; Zhao, Sheng-Bing Frontiers in Immunology, Vol. 9 https://doi.org/10.3389/fimmu.2018.00693	journal	April 2018
The antimicrobial activity of the appetite peptide hormone ghrelin Min, Christine; Ohta, Kouji; Kajiya, Mikihito Peptides, Vol. 36, Issue 2 https://doi.org/10.1016/j.peptides.2012.05.006	journal	August 2012
Construction of a cross-species cell landscape at single-cell level Wang, Renying; Zhang, Peijing; Wang, Jingjing Nucleic Acids Research, Vol. 51, Issue 2 https://doi.org/10.1093/nar/gkac633	journal	August 2022
Peptide Flexibility and the Hydrophobic Moment are Determinants to Evaluate the Clinical Potential of Magainins Balleza, Daniel The Journal of Membrane Biology, Vol. 256, Issue 4-6 https://doi.org/10.1007/s00232-023-00286-w	journal	April 2023

Similar Records

The effect of pancreatic polypeptide and peptide YY on pancreatic blood flow and pancreatic exocrine secretion in the anesthetized dog

Journal Article · 1991 · Pancreas; (USA) · OSTI ID:6060035

DeMar, A R; Lake, R; Fink, A S

Cell-selectivity of tryptophan and tyrosine in amphiphilic α-helical antimicrobial peptides against drug-resistant bacteria

Journal Article · 2018 · Biochemical and Biophysical Research Communications · OSTI ID:23107790

Lee, Min-Young; Park, Seong-Cheol; Jung, Myunghwan; +6 more

Effects of gastrointestinal hormonal peptides on the transformation of human peripheral lymphocytes

Journal Article · 1991 · Research Communications in Chemical Pathology and Pharmacology; (United States) · OSTI ID:5031734

Mihas, A A; Gibson, R G; Mihas, T A

Title: From a hunger-regulating hormone to an antimicrobial peptide: gastrointestinal derived circulating endocrine hormone-peptide YY exerts exocrine antimicrobial effects against selective gut microbiota

Citation Formats

References (25)

Similar Records

Related Subjects