The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A
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journal
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February 2014 |
Capturing a substrate in an activated RING E3/E2–SUMO complex
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August 2016 |
Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
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December 2006 |
Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks
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August 2012 |
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
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June 2013 |
Activation of UbcH5c∼Ub Is the Result of a Shift in Interdomain Motions of the Conjugate Bound to U-Box E3 Ligase E4B
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April 2013 |
Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18
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May 2017 |
Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination
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May 2020 |
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
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May 2010 |
Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome
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October 2014 |
RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
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September 2012 |
Preparation of nucleosome core particle from recombinant histones
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book
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January 1999 |
3D variability analysis: Resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM
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journal
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June 2021 |
RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
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June 2009 |
Integrated proteomic analysis of post-translational modifications by serial enrichment
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June 2013 |
RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling
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October 2007 |
Towards automated crystallographic structure refinement with phenix.refine
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March 2012 |
The role of dynamic conformational ensembles in biomolecular recognition
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October 2009 |
Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168
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January 2018 |
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
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October 2019 |
Structural insights into DNA double-strand break signaling
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January 2021 |
Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling
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journal
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March 2014 |
Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome
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April 2011 |
Structure and Histone Binding Properties of the Vps75-Rtt109 Chaperone-Lysine Acetyltransferase Complex
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May 2011 |
GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers
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September 2015 |
A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
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July 2012 |
Autologous K63 deubiquitylation within the BRCA1-A complex licenses DNA damage recognition
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August 2022 |
Structural Basis of Ubiquitin Recognition by Translesion Synthesis DNA Polymerase ι
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journal
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November 2010 |
Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106
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journal
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February 2012 |
BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer
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journal
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August 2012 |
The structural basis of modified nucleosome recognition by 53BP1
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journal
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July 2016 |
Addressing preferred specimen orientation in single-particle cryo-EM through tilting
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journal
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July 2017 |
Crystal Structure of UbcH5b∼Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2∼Ub Conjugates
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journal
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January 2010 |
Crystal structure of the nucleosome core particle at 2.8 Å resolution
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journal
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September 1997 |
KRAS Protein Stability Is Regulated through SMURF2: UBCH5 Complex-Mediated β-TrCP1 Degradation
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journal
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February 2014 |
Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4
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journal
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August 2010 |
UCSF Chimera?A visualization system for exploratory research and analysis
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journal
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January 2004 |
Structural basis for role of ring finger protein RNF168 RING domain
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journal
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January 2013 |
Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination
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journal
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May 2023 |
Architecture of the high mobility group nucleosomal protein 2-nucleosome complex as revealed by methyl-based NMR
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July 2011 |
BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation
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March 2019 |
Gctf: Real-time CTF determination and correction
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journal
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January 2016 |
Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia
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journal
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March 2011 |
New answers to the old RIDDLE: RNF168 and the DNA damage response pathway
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journal
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April 2021 |
Generation of nonhydrolyzable ubiquitin–histone mimics
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journal
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December 2014 |
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
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journal
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May 2011 |
A spectrophotometric assay for conjugation of ubiquitin and ubiquitin-like proteins
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journal
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November 2011 |
Structural basis of specific H2A K13/K15 ubiquitination by RNF168
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journal
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April 2019 |
Activation of a Primed RING E3-E2–Ubiquitin Complex by Non-Covalent Ubiquitin
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journal
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April 2015 |
Canonical sampling through velocity rescaling
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journal
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January 2007 |
Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
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journal
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May 2017 |
LINCS: A linear constraint solver for molecular simulations
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journal
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September 1997 |
BRCA1–BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes
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journal
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October 2023 |
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
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journal
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October 2015 |
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin
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journal
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March 2006 |
MolProbity : all-atom structure validation for macromolecular crystallography
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journal
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December 2009 |
Coot model-building tools for molecular graphics
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journal
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November 2004 |
Visualization of arrestin recruitment by a G-protein-coupled receptor
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journal
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June 2014 |
Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
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journal
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March 2011 |
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
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journal
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December 2012 |
53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
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journal
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April 2010 |
Histone ubiquitination in the DNA damage response
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journal
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August 2017 |
NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly
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journal
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February 2020 |
Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools
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journal
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July 2011 |
Molecular Insights into the Function of RING Finger (RNF)-containing Proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent Ubiquitylation
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journal
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May 2012 |
Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response
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journal
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November 2020 |
UCSF ChimeraX: Meeting modern challenges in visualization and analysis: UCSF ChimeraX Visualization System
|
journal
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September 2017 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
|
journal
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January 2010 |
BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination
|
journal
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July 2021 |
Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin
|
journal
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July 2021 |
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
|
journal
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February 2009 |
SOFAST-HMQC Experiments for Recording Two-dimensional Deteronuclear Correlation Spectra of Proteins within a Few Seconds
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journal
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December 2005 |
Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway
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journal
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May 2006 |
Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases
|
journal
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September 2012 |
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
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journal
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November 1995 |
Mechanisms of BRCA1–BARD1 nucleosome recognition and ubiquitylation
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journal
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July 2021 |
BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation
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journal
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June 2023 |
Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways
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journal
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April 2014 |
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
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journal
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July 2012 |
L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
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journal
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March 2018 |
A smooth particle mesh Ewald method
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journal
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November 1995 |
A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination
|
journal
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March 2006 |
Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination
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journal
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March 2011 |
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
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journal
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February 2017 |
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage
|
journal
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April 2017 |
Structural Basis of Heterochromatin Formation by Human HP1
|
journal
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February 2018 |
[20] Processing of X-ray diffraction data collected in oscillation mode
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book
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January 1997 |
Structure of the Yeast Mitochondrial Large Ribosomal Subunit
|
journal
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March 2014 |
Ring Finger Protein RNF169 Antagonizes the Ubiquitin-dependent Signaling Cascade at Sites of DNA Damage
|
journal
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June 2012 |
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
|
journal
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February 2009 |
BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1
|
journal
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February 2021 |
Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex
|
journal
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December 2018 |
RNF168 Promotes Noncanonical K27 Ubiquitination to Signal DNA Damage
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journal
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January 2015 |