Bacterial cellulose nanoparticles as a sustainable drug delivery platform for protein-based therapeutics

Journal Article · 20 March 2024 · RSC Applied Polymers

DOI: https://doi.org/10.1039/D3LP00184A · OSTI ID:2274986

Balistreri, Gabrielle N. ^[1]; Campbell, Ian R. ^[2]; Li, Xinqi ^[2]; Amorim, Julia ^[3]; Zhang, Shuai  ^[4]; Nance, Elizabeth  ^[1]; Roumeli, Eleftheria  ^[5]

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1. Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195, USA, Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA
2. Department of Materials Science and Engineering, University of Washington, Seattle, WA 98195, USA
3. Department of Biotechnology, Federal Rural University of Pernambuco, Recife PE 52171-900, Brazil
4. Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195, USA, Department of Materials Science and Engineering, University of Washington, Seattle, WA 98195, USA, Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA99354, USA
5. Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195, USA, Department of Materials Science and Engineering, University of Washington, Seattle, WA 98195, USA

BCNPs prepared from a kombucha co-culture can serve as a sustainable delivery platform for protein-based drugs. The amorphous nanoparticles form a mesh-like fibrillar network that is thermally stable and can be produced at scale.

• Sponsoring Organization: USDOE
• Grant/Contract Number: SC0019288
• OSTI ID: 2274986
• Journal Information: RSC Applied Polymers, Journal Name: RSC Applied Polymers Journal Issue: 2 Vol. 2; ISSN RAPSBD; ISSN 2755-371X
• Publisher: Royal Society of Chemistry (RSC)Copyright Statement
• Country of Publication: Country unknown/Code not available
• Language: English