Small partners, big impacts

Journal Article · 26 January 2022 · Nature Reviews Microbiology

DOI: https://doi.org/10.1038/s41579-022-00693-1 · OSTI ID:2228475

Wang, Ying  ^[1]; Northen, Trent R.  ^[2]

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1. USDOE Joint Genome Institute (JGI), Berkeley, CA (United States); Cornell University
2. USDOE Joint Genome Institute (JGI), Berkeley, CA (United States)

Bioactive metabolites mediate interactions between hosts and their microbiomes, often to improve the fitness of the holobionts. However, the mechanistic basis of these interactions and their contributions to fitness are poorly understood owing to their multifaceted nature. Finally, recent studies integrating metabolomics with genomic and functional data are beginning to fill this gap.

• Research Organization: Cornell Univ., Ithaca, NY (United States)
• Sponsoring Organization: USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science (BSS)
• Grant/Contract Number: SC0016364
• OSTI ID: 2228475
• Journal Information: Nature Reviews Microbiology, Journal Name: Nature Reviews Microbiology Journal Issue: 3 Vol. 20; ISSN 1740-1526
• Publisher: Springer NatureCopyright Statement
• Country of Publication: United States
• Language: English