Insight into the K channel's selectivity from binding of K + , Na + and water to N -methylacetamide
- Center for Integrated Nanotechnologies, Sandia National Laboratories, Albuquerque, NM 87185, USA
Binding site occupancy and the mechanism of K selectivity involve multiple K binding in multiple neighboring layers, or sites, of the K channel selectivity filter.
- Sponsoring Organization:
- USDOE
- Grant/Contract Number:
- NONE; NA0003525
- OSTI ID:
- 2202521
- Alternate ID(s):
- OSTI ID: 2530861
- Journal Information:
- Faraday Discussions, Journal Name: Faraday Discussions Vol. 249; ISSN FDISE6; ISSN 1359-6640
- Publisher:
- Royal Society of Chemistry (RSC)Copyright Statement
- Country of Publication:
- United Kingdom
- Language:
- English
Similar Records
Structural and Thermodynamic Properties of Selective Ion Binding in a K+ Channel
Mechanism of potassium-channel selectivity revealed by Na[superscript +] and Li[superscript +] binding sites within the KcsA pore
Novel insights into K[superscript +] selectivity from high-resolution structures of an open K[superscript +] channel pore
Journal Article
·
2007
· PLoS Biology
·
OSTI ID:960132
Mechanism of potassium-channel selectivity revealed by Na[superscript +] and Li[superscript +] binding sites within the KcsA pore
Journal Article
·
2010
· Nat. Struct. Mol. Biol.
·
OSTI ID:1006053
+3 more
Novel insights into K[superscript +] selectivity from high-resolution structures of an open K[superscript +] channel pore
Journal Article
·
2010
· Nat. Struct. Mol. Biol.
·
OSTI ID:1002556