Inhibition of ethylene involved in resistance to E. turcicum in an exotic-derived double haploid maize population

Lipps, Sarah; Lipka, Alexander E.; Mideros, Santiago; Jamann, Tiffany

doi:10.3389/fpls.2023.1272951

Title: Inhibition of ethylene involved in resistance to E. turcicum in an exotic-derived double haploid maize population

Journal Article · 06 October 2023 · Frontiers in Plant Science

DOI: https://doi.org/10.3389/fpls.2023.1272951 · OSTI ID:2007974

Lipps, Sarah; Lipka, Alexander E.; Mideros, Santiago; Jamann, Tiffany

Northern corn leaf blight (NCLB) is an economically important disease of maize. While the genetic architecture of NCLB has been well characterized, the pathogen is known to overcome currently deployed resistance genes, and the role of hormones in resistance to NCLB is an area of active research. The objectives of the study were (i) to identify significant markers associated with resistance to NCLB, (ii) to identify metabolic pathways associated with NCLB resistance, and (iii) to examine role of ethylene in resistance to NCLB. We screened 252 lines from the exotic-derived double haploid BGEM maize population for resistance to NCLB in both field and greenhouse environments. We used a genome wide association study (GWAS) and stepwise regression to identify four markers associated with resistance, followed by a pathway association study tool (PAST) to identify important metabolic pathways associated with disease severity and incubation period. The ethylene synthesis pathway was significant for disease severity and incubation period. We conducted a greenhouse assay in which we inhibited ethylene to examine the role of ethylene in resistance to NCLB. We observed a significant increase in incubation period and a significant decrease in disease severity between plants treated with the ethylene inhibitor and mock-treated plants. Our study confirms the potential of the BGEM population as a source of novel alleles for resistance. We also confirm the role of ethylene in resistance to NCLB and contribute to the growing body of literature on ethylene and disease resistance in monocots.

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Research Organization:: Univ. of Illinois at Urbana-Champaign, IL (United States)

Sponsoring Organization:: USDOE; USDOE Office of Science (SC)

Grant/Contract Number:: SC0019189

OSTI ID:: 2007974

Alternate ID(s):: OSTI ID: 2472275

Journal Information:: Frontiers in Plant Science, Journal Name: Frontiers in Plant Science Vol. 14; ISSN 1664-462X

Publisher:: Frontiers Media SACopyright Statement

Country of Publication:: Switzerland

Language:: English

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