Quadrupole and multi-collector ICP-MS analysis of 226Ra in brain from a radium dial painter

Arbova, D. L.; Tolmachev, S. Y.; Brockman, J. D.

doi:10.1039/d1ja00393c

Title: Quadrupole and multi-collector ICP-MS analysis of ²²⁶Ra in brain from a radium dial painter

Journal Article · 19 May 2022 · Journal of Analytical Atomic Spectrometry

DOI: https://doi.org/10.1039/d1ja00393c · OSTI ID:1978799

Arbova, D. L. ^[1];

^[2];

^[3]

University of Missouri, Columbia, MO (United States); OSTI
Washington State University, Pullman, WA (United States)
University of Missouri, Columbia, MO (United States)

We report two ICP-MS methods were developed to measure the radiotoxic isotope ²²⁶Ra in brain tissues from a radium dial painter worker. The first method was a direct analysis of acid digested samples using quadrupole ICP-MS. The instrumental LOD of ²²⁶Ra was 0.1 ng kg^-1. Polyatomic interferences at m/z 226 were investigated and Pb was identified from a polyatomic interferent in an in-house sample prepared from bovine brain, with a 226/208 formation ratio of 4 × 10^-8. The quadrupole ICP-MS method was also used to measure levels of beryllium, strontium, and uranium. A second method was developed that included cation-exchange chromatography to separate ²²⁶Ra followed by analysis with sector field MC-ICP-MS. The instrumental LOD for the cation exchange method with MC-ICP-MS detection was 0.5 pg kg^-1 (19 mBq kg^-1). The measured concentrations of ²²⁶Ra in different brain regions ranged from 0.09–0.72 ng kg^-1 (3.3–27 Bq kg^-1) and radium was non-uniformly distributed in the brain.

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Research Organization:: Washington State University, Pullman, WA (United States)

Sponsoring Organization:: USDOE Office of Environment, Health, Safety and Security (AU); Nuclear Regulatory Commission (USNRC)

Grant/Contract Number:: HS0000073

OSTI ID:: 1978799

Journal Information:: Journal of Analytical Atomic Spectrometry, Journal Name: Journal of Analytical Atomic Spectrometry Journal Issue: 6 Vol. 37; ISSN 0267-9477

Publisher:: Royal Society of ChemistryCopyright Statement

Country of Publication:: United States

Language:: English

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