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Title: CCL2 promotes lymphatic metastasis via activating RhoA and Rac1 pathway and predict prognosis to some extent in tongue cancer

Journal Article · · Cancer Biology & Therapy
 [1];  [1];  [2];  [2];  [2]; ORCiD logo [2];  [3]
  1. State Key Laboratory of Oral Disease &, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China, Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China
  2. State Key Laboratory of Oral Disease &, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China, Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu, China
  3. Yunnan Key Laboratory of Stomatology, The Affiliated Hospital of Stomatology, School of Stomatology, Kunming Medical University, Kunming, Yunnan, PR China

Not Available

Sponsoring Organization:
USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research
OSTI ID:
1972414
Journal Information:
Cancer Biology & Therapy, Journal Name: Cancer Biology & Therapy Journal Issue: 1 Vol. 24; ISSN 1538-4047
Publisher:
Informa UK LimitedCopyright Statement
Country of Publication:
Country unknown/Code not available
Language:
English

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CCL2 induces prostate cancer transendothelial cell migration via activation of the small GTPase Rac journal August 2008
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Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic journal January 2005
CCL2 Protects Prostate Cancer PC3 Cells from Autophagic Death via Phosphatidylinositol 3-Kinase/AKT-dependent Survivin Up-regulation journal September 2008
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Altered phenotype of lymphatic endothelial cells induced by highly metastatic OTSCC cells contributed to the lymphatic metastasis of OTSCC cells journal March 2010
Oral cancer cells with different potential of lymphatic metastasis displayed distinct biologic behaviors and gene expression profiles journal February 2010
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B7-H3 Suppresses Antitumor Immunity via the CCL2–CCR2–M2 Macrophage Axis and Contributes to Ovarian Cancer Progression journal November 2021
Association of CCL2 with Lymph Node Metastasis and Macrophage Infiltration in Oral Cavity and Lip Squamous Cell Carcinoma journal January 2008
Oral Cancer Screening: Past, Present, and Future journal May 2021
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression journal July 2000
CCL2/CCR2 signaling in cancer pathogenesis journal May 2020
PLEK2 promotes gallbladder cancer invasion and metastasis through EGFR/CCL2 pathway journal June 2019
Progression-Free Survival: Meaningful or Simply Measurable? journal April 2012
High Level of Plasma Matrix Metalloproteinase-11 Is Associated with Clinicopathological Characteristics in Patients with Oral Squamous Cell Carcinoma journal November 2014
CCL2 is a Potent Regulator of Prostate Cancer Cell Migration and Proliferation journal July 2006
Cancer statistics, 2019 journal October 2018
Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses journal September 2020

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