Integrative visualization of the molecular structure of a cellular microdomain

Goodsell, David S.; Lasker, Keren

doi:10.1002/pro.4577

Title: Integrative visualization of the molecular structure of a cellular microdomain

Journal Article · 13 February 2023 · Protein Science

DOI: https://doi.org/10.1002/pro.4577 · OSTI ID:1924563

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Department of Integrative Structural and Computational Biology The Scripps Research Institute La Jolla California USA, Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey Piscataway New Jersey USA, Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey Piscataway New Jersey USA, Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey New Brunswick New Jersey USA
Department of Integrative Structural and Computational Biology The Scripps Research Institute La Jolla California USA

Abstract An integrative approach to visualization is used to create a visual snapshot of the structural biology of the polar microdomain of Caulobacter crescentus . The visualization is based on the current state of molecular and cellular knowledge of the microdomain and its cellular context. The collaborative process of researching and executing the visualization has identified aspects that are well determined and areas that require further study. The visualization is useful for dissemination, education, and outreach, and the study lays the groundwork for future 3D modeling and simulation of this well‐studied example of a cellular condensate.

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Research Organization:: Rutgers University, Piscataway, NJ (United States)

Sponsoring Organization:: National Institutes of Health (NIH); National Science Foundation (NSF); USDOE; USDOE Office of Science (SC)

Grant/Contract Number:: SC0019749

OSTI ID:: 1924563

Journal Information:: Protein Science, Journal Name: Protein Science Journal Issue: 3 Vol. 32; ISSN 0961-8368

Publisher:: Wiley Blackwell (John Wiley & Sons)Copyright Statement

Country of Publication:: United Kingdom

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
Biochemistry & Molecular Biology
Caulobacter crescentus
PopZ
cellular condensate
integrative structural biology
intrinsically disordered protein
molecular visualization

Title: Integrative visualization of the molecular structure of a cellular microdomain

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References (94)

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