Nemolizumab in patients with moderate-to-severe atopic dermatitis: Randomized, phase II, long-term extension study

Kabashima, Kenji; Furue, Masutaka; Hanifin, Jon M.; Pulka, Grazyna; Wollenberg, Andreas; Galus, Ryszard; Etoh, Takafumi; Mihara, Ryosuke; Nakano, Miwa; Ruzicka, Thomas

doi:10.1016/j.jaci.2018.03.018

Title: Nemolizumab in patients with moderate-to-severe atopic dermatitis: Randomized, phase II, long-term extension study

Journal Article · 01 October 2018 · Journal of Allergy and Clinical Immunology

DOI: https://doi.org/10.1016/j.jaci.2018.03.018 · OSTI ID:1898448

Kabashima, Kenji; Furue, Masutaka; Hanifin, Jon M.; Pulka, Grazyna; Wollenberg, Andreas; Galus, Ryszard; Etoh, Takafumi; Mihara, Ryosuke; Nakano, Miwa; Ruzicka, Thomas

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Sponsoring Organization:: USDOE Office of Environmental Management (EM), Acquisition and Project Management

OSTI ID:: 1898448

Journal Information:: Journal of Allergy and Clinical Immunology, Journal Name: Journal of Allergy and Clinical Immunology Journal Issue: 4 Vol. 142; ISSN 0091-6749

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

References (27)

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Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin Esaki, Hitokazu; Brunner, Patrick M.; Renert-Yuval, Yael Journal of Allergy and Clinical Immunology, Vol. 138, Issue 6 https://doi.org/10.1016/j.jaci.2016.07.013	journal	December 2016
Advances in atopic dermatitis in 2015 Nomura, Takashi; Kabashima, Kenji Journal of Allergy and Clinical Immunology, Vol. 138, Issue 6 https://doi.org/10.1016/j.jaci.2016.10.004	journal	December 2016
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Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice Dillon, Stacey R.; Sprecher, Cindy; Hammond, Angela Nature Immunology, Vol. 5, Issue 7 https://doi.org/10.1038/ni1084	journal	June 2004
Anti–Interleukin-31 Receptor A Antibody for Atopic Dermatitis Ruzicka, Thomas; Hanifin, Jon M.; Furue, Masutaka New England Journal of Medicine, Vol. 376, Issue 9 https://doi.org/10.1056/NEJMoa1606490	journal	March 2017
Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis Simpson, Eric L.; Bieber, Thomas; Guttman-Yassky, Emma New England Journal of Medicine, Vol. 375, Issue 24 https://doi.org/10.1056/NEJMoa1610020	journal	December 2016
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Title: Nemolizumab in patients with moderate-to-severe atopic dermatitis: Randomized, phase II, long-term extension study

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