Nanoparticles caged with DNA nanostructures

Jergens, Elizabeth; Winter, Jessica O.

doi:10.1016/j.copbio.2021.12.010

Title: Nanoparticles caged with DNA nanostructures

Journal Article · 09 January 2022 · Current Opinion in Biotechnology

DOI: https://doi.org/10.1016/j.copbio.2021.12.010 · OSTI ID:1887783

Jergens, Elizabeth ^[1];

^[2]

The Ohio State Univ., Columbus, OH (United States); The Ohio State University
The Ohio State Univ., Columbus, OH (United States)

Nanoparticles (NPs) offer many benefits in biotechnology because of their small size and unique properties. Furthermore, many applications require precise positioning of the NPs or biological targeting molecules on their surfaces. DNA cages constructed from DNA tile, origami, or wireframe nanostructures offer a promising path forward because of their simplicity and programmability that can be used to generate complex, dynamic 2D and 3D geometries. Such materials can be used to pattern DNA on NP surfaces and organize NPs into specific supramolecular structures. DNA-caged NPs can be implemented in biosensing and drug delivery applications with cavities precisely designed to encapsulate-specific biomolecules. Ultimately, such approaches provide a springboard for future DNA robot designs that will enable controlled interactions with biological systems.

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Research Organization:: The Ohio State Univ., Columbus, OH (United States)

Sponsoring Organization:: USDOE; USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0017270

OSTI ID:: 1887783

Journal Information:: Current Opinion in Biotechnology, Journal Name: Current Opinion in Biotechnology Vol. 74; ISSN 0958-1669

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

References (48)

DNA Nanotechnology‐Based Biosensors and Therapeutics Shen, Luyao; Wang, Pengfei; Ke, Yonggang Advanced Healthcare Materials, Vol. 10, Issue 15 https://doi.org/10.1002/adhm.202002205	journal	June 2021
Icosahedral DNA Nanocapsules by Modular Assembly Bhatia, Dhiraj; Mehtab, Shabana; Krishnan, Ramya Angewandte Chemie International Edition, Vol. 48, Issue 23 https://doi.org/10.1002/anie.200806000	journal	May 2009
Non-covalent Single Transcription Factor Encapsulation Inside a DNA Cage Crawford, Robert; Erben, Christoph M.; Periz, Javier Angewandte Chemie International Edition, Vol. 52, Issue 8 https://doi.org/10.1002/anie.201207914	journal	January 2013
Programmable Assembly of Nano‐architectures through Designing Anisotropic DNA Origami Patches Wang, Mingyang; Dai, Lizhi; Duan, Jialin Angewandte Chemie International Edition, Vol. 59, Issue 16 https://doi.org/10.1002/anie.201913958	journal	February 2020
Programmed Nanopatterning of Organic/Inorganic Nanoparticles Using Nanometer-Scale Wells Embedded in a DNA Origami Scaffold Kuzuya, Akinori; Koshi, Naohiro; Kimura, Mayumi Small, Vol. 6, Issue 23 https://doi.org/10.1002/smll.201001484	journal	November 2010
Highly tumor-specific DNA nanostructures discovered by in vivo screening of a nucleic acid cage library and their applications in tumor-targeted drug delivery Kim, Kyoung-Ran; Kang, Seong Jae; Lee, A-Young Biomaterials, Vol. 195 https://doi.org/10.1016/j.biomaterials.2018.12.026	journal	March 2019
Molecular Printing with DNA Nanotechnology Rizzuto, Felix J.; Trinh, Tuan; Sleiman, Hanadi F. Chem, Vol. 6, Issue 7 https://doi.org/10.1016/j.chempr.2020.06.012	journal	July 2020
Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs Kim, Kyoung-Ran; Kim, Hyo Young; Lee, Yong-Deok Journal of Controlled Release, Vol. 243 https://doi.org/10.1016/j.jconrel.2016.10.015	journal	December 2016
The path towards functional nanoparticle-DNA origami composites Johnson, Joshua A.; Dehankar, Abhilasha; Robbins, Ariel Materials Science and Engineering: R: Reports, Vol. 138 https://doi.org/10.1016/j.mser.2019.06.003	journal	October 2019
Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages Raniolo, Sofia; Vindigni, Giulia; Ottaviani, Alessio Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 14, Issue 4 https://doi.org/10.1016/j.nano.2018.02.002	journal	June 2018
DNA nanotechnology enhanced single-molecule biosensing and imaging Fu, Shengnan; Zhang, Tengfang; Jiang, Huanling TrAC Trends in Analytical Chemistry, Vol. 140 https://doi.org/10.1016/j.trac.2021.116267	journal	July 2021
Maximizing DNA Loading on a Range of Gold Nanoparticle Sizes Hurst, Sarah J.; Lytton-Jean, Abigail K. R.; Mirkin, Chad A. Analytical Chemistry, Vol. 78, Issue 24 https://doi.org/10.1021/ac0613582	journal	December 2006
DNA Nanocages Chandrasekaran, Arun Richard; Levchenko, Oksana Chemistry of Materials, Vol. 28, Issue 16 https://doi.org/10.1021/acs.chemmater.6b02546	journal	August 2016
DNA Functional Materials Assembled from Branched DNA: Design, Synthesis, and Applications Dong, Yuhang; Yao, Chi; Zhu, Yi Chemical Reviews, Vol. 120, Issue 17 https://doi.org/10.1021/acs.chemrev.0c00294	journal	July 2020
Three-Dimensional Molecular Transfer from DNA Nanocages to Inner Gold Nanoparticle Surfaces Xie, Nuli; Liu, Shiyuan; Fang, Hongmei ACS Nano, Vol. 13, Issue 4 https://doi.org/10.1021/acsnano.8b09147	journal	March 2019
Dynamic Nanoparticle Assemblies Wang, Libing; Xu, Liguang; Kuang, Hua Accounts of Chemical Research, Vol. 45, Issue 11 https://doi.org/10.1021/ar200305f	journal	March 2012
Templated Synthesis of DNA Nanotubes with Controlled, Predetermined Lengths Lo, Pik Kwan; Altvater, Florian; Sleiman, Hanadi F. Journal of the American Chemical Society, Vol. 132, Issue 30, p. 10212-10214 https://doi.org/10.1021/ja1017442	journal	August 2010
Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route Zhang, Xu; Servos, Mark R.; Liu, Juewen Journal of the American Chemical Society, Vol. 134, Issue 17 https://doi.org/10.1021/ja3014055	journal	April 2012
Self-Assembly of Chiral Nanoparticle Pyramids with Strong R / S Optical Activity Yan, Wenjing; Xu, Liguang; Xu, Chuanlai Journal of the American Chemical Society, Vol. 134, Issue 36 https://doi.org/10.1021/ja3066336	journal	September 2012
Pyramidal and Chiral Groupings of Gold Nanocrystals Assembled Using DNA Scaffolds Mastroianni, Alexander J.; Claridge, Shelley A.; Alivisatos, A. Paul Journal of the American Chemical Society, Vol. 131, Issue 24, p. 8455-8459 https://doi.org/10.1021/ja808570g	journal	June 2009
Gold Nanoparticle Self-Similar Chain Structure Organized by DNA Origami Ding, Baoquan; Deng, Zhengtao; Yan, Hao Journal of the American Chemical Society, Vol. 132, Issue 10 https://doi.org/10.1021/ja9101198	journal	March 2010
Self-Assembly of Molecule-like Nanoparticle Clusters Directed by DNA Nanocages Li, Yulin; Liu, Zhiyu; Yu, Guimei Journal of the American Chemical Society, Vol. 137, Issue 13 https://doi.org/10.1021/jacs.5b01196	journal	March 2015
Development of DNA Nanostructures for High-Affinity Binding to Human Serum Albumin Lacroix, Aurélie; Edwardson, Thomas G. W.; Hancock, Mark A. Journal of the American Chemical Society, Vol. 139, Issue 21 https://doi.org/10.1021/jacs.7b02917	journal	May 2017
Shape-Controlled Synthesis of Gold Nanostructures Using DNA Origami Molds Helmi, Seham; Ziegler, Christoph; Kauert, Dominik J. Nano Letters, Vol. 14, Issue 11 https://doi.org/10.1021/nl503441v	journal	October 2014
DNA Cage Delivery to Mammalian Cells Walsh, Anthony S.; Yin, HaiFang; Erben, Christoph M. ACS Nano, Vol. 5, Issue 7 https://doi.org/10.1021/nn2005574	journal	June 2011
Synthesis from DNA of a molecule with the connectivity of a cube Chen, Junghuei; Seeman, Nadrian C. Nature, Vol. 350, Issue 6319 https://doi.org/10.1038/350631a0	journal	April 1991
A DNA-based method for rationally assembling nanoparticles into macroscopic materials Mirkin, Chad A.; Letsinger, Robert L.; Mucic, Robert C. Nature, Vol. 382, Issue 6592, p. 607-609 https://doi.org/10.1038/382607a0	journal	August 1996
Organization of 'nanocrystal molecules' using DNA Alivisatos, A. Paul; Johnsson, Kai P.; Peng, Xiaogang Nature, Vol. 382, Issue 6592 https://doi.org/10.1038/382609a0	journal	August 1996
Folding DNA to create nanoscale shapes and patterns Rothemund, Paul W. K. Nature, Vol. 440, Issue 7082, p. 297-302 https://doi.org/10.1038/nature04586	journal	March 2006
A synthetic icosahedral DNA-based host–cargo complex for functional in vivo imaging Bhatia, Dhiraj; Surana, Sunaina; Chakraborty, Saikat Nature Communications, Vol. 2, Issue 1 https://doi.org/10.1038/ncomms1337	journal	June 2011
Quantum dot-loaded monofunctionalized DNA icosahedra for single-particle tracking of endocytic pathways Bhatia, Dhiraj; Arumugam, Senthil; Nasilowski, Michel Nature Nanotechnology, Vol. 11, Issue 12 https://doi.org/10.1038/nnano.2016.150	journal	August 2016
Cell-targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules Veetil, Aneesh T.; Chakraborty, Kasturi; Xiao, Kangni Nature Nanotechnology, Vol. 12, Issue 12 https://doi.org/10.1038/nnano.2017.159	journal	August 2017
Encapsulation of a gold nanoparticle in a DNA origami container Kuzuya, Akinori; Kaino, Masafumi; Hashizume, Mirai Polymer Journal, Vol. 47, Issue 2 https://doi.org/10.1038/pj.2014.128	journal	December 2014
Ordered three-dimensional nanomaterials using DNA-prescribed and valence-controlled material voxels Tian, Ye; Lhermitte, Julien R.; Bai, Lin Nature Materials, Vol. 19, Issue 7 https://doi.org/10.1038/s41563-019-0550-x	journal	January 2020
DNA-caged gold nanoparticles for controlled release of doxorubicin triggered by a DNA enzyme and pH Zhang, Zi-Mou; Gao, Peng-Cheng; Wang, Zhi-Fei Chemical Communications, Vol. 51, Issue 65 https://doi.org/10.1039/C5CC05164A	journal	January 2015
Periodic nanostructures: preparation, properties and applications Yin, Hang; Xing, Kaijian; Zhang, Yurou Chemical Society Reviews, Vol. 50, Issue 11 https://doi.org/10.1039/D0CS01146K	journal	January 2021
Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold Endo, Masayuki; Yang, Yangyang; Emura, Tomoko Chemical Communications, Vol. 47, Issue 38 https://doi.org/10.1039/c1cc13984c	journal	January 2011
Programmable motion of DNA origami mechanisms Marras, Alexander E.; Zhou, Lifeng; Su, Hai-Jun Proceedings of the National Academy of Sciences, Vol. 112, Issue 3 https://doi.org/10.1073/pnas.1408869112	journal	January 2015
DNA cytoskeleton for stabilizing artificial cells Kurokawa, Chikako; Fujiwara, Kei; Morita, Masamune Proceedings of the National Academy of Sciences, Vol. 114, Issue 28 https://doi.org/10.1073/pnas.1702208114	journal	June 2017
Quantum dots–DNA bioconjugates: synthesis to applications Banerjee, Anusuya; Pons, Thomas; Lequeux, Nicolas Interface Focus, Vol. 6, Issue 6 https://doi.org/10.1098/rsfs.2016.0064	journal	December 2016
A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads Douglas, S. M.; Bachelet, I.; Church, G. M. Science, Vol. 335, Issue 6070 https://doi.org/10.1126/science.1214081	journal	February 2012
Casting inorganic structures with DNA molds Sun, W.; Boulais, E.; Hakobyan, Y. Science, Vol. 346, Issue 6210 https://doi.org/10.1126/science.1258361	journal	October 2014
Diamond family of nanoparticle superlattices Liu, W.; Tagawa, M.; Xin, H. L. Science, Vol. 351, Issue 6273, p. 582-586 https://doi.org/10.1126/science.aad2080	journal	February 2016
Nanoscale Robots Exhibiting Quorum Sensing Amir, Yaniv; Abu-Horowitz, Almogit; Werfel, Justin Artificial Life, Vol. 25, Issue 3 https://doi.org/10.1162/artl_a_00293	journal	August 2019
Thought-Controlled Nanoscale Robots in a Living Host Arnon, Shachar; Dahan, Nir; Koren, Amir PLOS ONE, Vol. 11, Issue 8 https://doi.org/10.1371/journal.pone.0161227	journal	August 2016
Nanotechnology-enabled biomedical engineering: Current trends, future scopes, and perspectives Ray, Shariqsrijon Sinha; Bandyopadhyay, Jayita Nanotechnology Reviews, Vol. 10, Issue 1 https://doi.org/10.1515/ntrev-2021-0052	journal	January 2021
Applications of Optically Controlled Gold Nanostructures in Biomedical Engineering Phummirat, Pisrut; Mann, Nicholas; Preece, Daryl Frontiers in Bioengineering and Biotechnology, Vol. 8 https://doi.org/10.3389/fbioe.2020.602021	journal	January 2021
Increasing Complexity in Wireframe DNA Nanostructures Piskunen, Petteri; Nummelin, Sami; Shen, Boxuan Molecules, Vol. 25, Issue 8 https://doi.org/10.3390/molecules25081823	journal	April 2020

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