Adsorptive separation and recovery of triacetic acid lactone from fermentation broth

Journal Article · 15 September 2022 · Biofuels, Bioproducts & Biorefining

DOI: https://doi.org/10.1002/bbb.2427 · OSTI ID:1887635

Singh, Ramkrishna  ^[1]; Bhagwat, Sarang S. ^[2]; Viswanathan, Mothi Bharath  ^[1]; Cortés‐Peña, Yoel R. ^[2]; Eilts, Kristen K. ^[3]; McDonough, Grace ^[4]; Cao, Mingfeng ^[5]; Guest, Jeremy S. ^[6]; Zhao, Huimin ^[5]; Singh, Vijay  ^[1]

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1. DOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) University of Illinois at Urbana‐Champaign Urbana IL USA, Department of Agricultural and Biological Engineering University of Illinois at Urbana‐Champaign Urbana IL USA
2. DOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) University of Illinois at Urbana‐Champaign Urbana IL USA, Department of Civil and Environmental Engineering University of Illinois at Urbana‐Champaign, 3221 Newmark Civil Engineering Laboratory Urbana IL USA
3. DOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) University of Illinois at Urbana‐Champaign Urbana IL USA
4. Department of Agricultural and Biological Engineering University of Illinois at Urbana‐Champaign Urbana IL USA
5. DOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) University of Illinois at Urbana‐Champaign Urbana IL USA, Department of Chemical and Biomolecular Engineering University of Illinois at Urbana‐Champaign Urbana IL USA
6. DOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) University of Illinois at Urbana‐Champaign Urbana IL USA, Department of Civil and Environmental Engineering University of Illinois at Urbana‐Champaign, 3221 Newmark Civil Engineering Laboratory Urbana IL USA, Institute for Sustainability, Energy, and Environment (iSEE) University of Illinois at Urbana‐Champaign Urbana IL USA

Abstract Triacetic acid lactone (TAL), an emerging bioprivileged molecule, can be produced microbially and further chemically upgraded to several high‐value chemicals. In this work, several acidic and basic ion‐exchange resins and activated charcoal were evaluated for their ability to adsorb microbially produced TAL. Activated charcoal and a weak base resin, Dowex 66, showed similar TAL adsorption capacity of 0.18 ± 0.002 g/g. At 15% w/v activated charcoal, about 98% of TAL present in fermentation broth could be adsorbed. Further, ethanol washing allowed recovery of 72% of adsorbed TAL. A biorefinery producing TAL from sucrose was designed, simulated, and evaluated (through technoeconomic analysis) under uncertainty, for an estimated TAL minimum product selling price (MPSP) of $4.27/kg ($3.71–4.94/kg; 5th–95th percentiles) given the current state of technology and $2.83/kg ($2.46–3.29/kg) following potential near‐term improvements to fermentation. This work provides an adsorptive process for the recovery of microbially produced TAL that can be upgraded chemically to a range of industrial products. © 2022 The Authors. Biofuels, Bioproducts and Biorefining published by Society of Industrial Chemistry and John Wiley & Sons Ltd.

• Sponsoring Organization: USDOE
• Grant/Contract Number: SC0018420
• OSTI ID: 1887635
• Journal Information: Biofuels, Bioproducts & Biorefining, Journal Name: Biofuels, Bioproducts & Biorefining Journal Issue: 1 Vol. 17; ISSN 1932-104X
• Publisher: Wiley Blackwell (John Wiley & Sons)Copyright Statement
• Country of Publication: United Kingdom
• Language: English