Mechanistic Studies of a Skatole-Forming Glycyl Radical Enzyme Suggest Reaction Initiation via Hydrogen Atom Transfer

Fu, Beverly; Nazemi, Azadeh; Levin, Benjamin J.; Yang, Zhongyue; Kulik, Heather J.; Balskus, Emily P.

doi:10.1021/jacs.1c13580

Title: Mechanistic Studies of a Skatole-Forming Glycyl Radical Enzyme Suggest Reaction Initiation via Hydrogen Atom Transfer

Journal Article · 14 June 2022 · Journal of the American Chemical Society

DOI: https://doi.org/10.1021/jacs.1c13580 · OSTI ID:1872508

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Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States, Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts 02138, United States

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Research Organization:: Harvard Univ., Cambridge, MA (United States)

Sponsoring Organization:: Alan T. Waterman; Howard Hughes Medical Institute (HHMI); NSF Graduate Research Fellowships; National Science Foundation (NSF); USDOE; USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0019112

OSTI ID:: 1872508

Journal Information:: Journal of the American Chemical Society, Journal Name: Journal of the American Chemical Society Journal Issue: 25 Vol. 144; ISSN 0002-7863

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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