Genomic Features and Pervasive Negative Selection in Rhodanobacter Strains Isolated from Nitrate and Heavy Metal Contaminated Aquifer

Peng, Mu; Wang, Dongyu; Lui, Lauren M.; Nielsen, Torben; Tian, Renmao; Kempher, Megan L.; Tao, Xuanyu; Pan, Chongle; Chakraborty, Romy; Deutschbauer, Adam M.; Thorgersen, Michael P.; Adams, Michael W. W.; Fields, Matthew W.; Hazen, Terry C.; Arkin, Adam P.; Zhou, Aifen; Zhou, Jizhong; DeAngelis, ed., Kristen M.

doi:10.1128/spectrum.02591-21

Title: Genomic Features and Pervasive Negative Selection in Rhodanobacter Strains Isolated from Nitrate and Heavy Metal Contaminated Aquifer

Journal Article · 22 February 2022 · Microbiology Spectrum

DOI: https://doi.org/10.1128/spectrum.02591-21 · OSTI ID:1843281

Peng, Mu ^[1]; Wang, Dongyu ^[2]; Lui, Lauren M. ^[3]; Nielsen, Torben ^[3]; Tian, Renmao ^[1];

^[1]; Tao, Xuanyu ^[1];

^[2];

^[4]; Deutschbauer, Adam M. ^[5]; Thorgersen, Michael P. ^[6];

^[6]; Fields, Matthew W. ^[7];

^[8]; Arkin, Adam P. ^[9];

^[1]; Zhou, Jizhong ^[10]; DeAngelis, ed., Kristen M.

Institute for Environmental Genomics, Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States
Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States
Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States
Earth and Environmental Sciences Area, Lawrence Berkeley National Laboratory, Berkeley, California, United States
Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States, Department of Plant and Microbial Biology, University of California, Berkeley, California, United States
Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States
Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, United States, Center for Biofilm Engineering, Montana State University, Bozeman, Montana, United States
Department of Civil and Environmental Engineering, University of Tennessee, Knoxville, Tennessee, United States, Oak Ridge National Laboratory, Bioscience Division, Oak Ridge, Tennessee, United States
Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States, Department of Bioengineering, University of California, Berkeley, California, United States
Institute for Environmental Genomics; Department of Microbiology and Plant Biology; University of Oklahoma; Norman; Oklahoma; United States; Earth and Environmental Sciences Area; Lawrence Berkeley National Laboratory; Berkeley; California; United States; State Key Joint Laboratory of Environment Simulation and Pollution Control; School of Environment; Tsinghua University; Beijing; China; School of Civil Engineering and Environmental Sciences; University of Oklahoma; Norman; Oklahoma; United States

Despite the dominance of Rhodanobacter species in the subsurface of the contaminated Oak Ridge Reservation (ORR) site, very little is known about the mechanisms underlying their adaptions to the various stressors present at ORR. Recently, multiple Rhodanobacter strains have been isolated from the ORR groundwater samples from several wells with varying geochemical properties.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE; USDOE Office of Science (SC), Biological and Environmental Research (BER)

Grant/Contract Number:: AC02-05CH11231; AC05-00OR22725

OSTI ID:: 1843281

Journal Information:: Microbiology Spectrum, Journal Name: Microbiology Spectrum Journal Issue: 1 Vol. 10; ISSN 2165-0497

Publisher:: American Society for MicrobiologyCopyright Statement

Country of Publication:: United States

Language:: English

References (69)

N6-Methyladenine: A Conserved and Dynamic DNA Mark O’Brown, Zach Klapholz; Greer, Eric Lieberman DNA Methyltransferases - Role and Function https://doi.org/10.1007/978-3-319-43624-1_10	book	January 2016
Comparative Genomics of Nitrogen Cycling Pathways in Bacteria and Archaea Albright, Michaeline B. N.; Timalsina, Bibek; Martiny, Jennifer B. H. Microbial Ecology, Vol. 77, Issue 3 https://doi.org/10.1007/s00248-018-1239-4	journal	August 2018
Denitrifying genes in bacterial and Archaeal genomes Philippot, Laurent Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, Vol. 1577, Issue 3 https://doi.org/10.1016/S0167-4781(02)00420-7	journal	September 2002
KaKs_Calculator 2.0: A Toolkit Incorporating Gamma-Series Methods and Sliding Window Strategies Wang, Dapeng; Zhang, Yubin; Zhang, Zhang Genomics, Proteomics & Bioinformatics, Vol. 8, Issue 1 https://doi.org/10.1016/S1672-0229(10)60008-3	journal	March 2010
Nitrification/denitrification shaped the mercury-oxidizing microbial community for simultaneous Hg0 and NO removal Huang, Zhenshan; Wei, Zaishan; Xiao, Xiaoliang Bioresource Technology, Vol. 274 https://doi.org/10.1016/j.biortech.2018.11.069	journal	February 2019
Bacterial Autoimmunity Due to a Restriction-Modification System Pleška, Maroš; Qian, Long; Okura, Reiko Current Biology, Vol. 26, Issue 3 https://doi.org/10.1016/j.cub.2015.12.041	journal	February 2016
Comparative genomics: the bacterial pan-genome Tettelin, Hervé; Riley, David; Cattuto, Ciro Current Opinion in Microbiology, Vol. 11, Issue 5 https://doi.org/10.1016/j.mib.2008.09.006	journal	October 2008
Ten years of pan-genome analyses Vernikos, George; Medini, Duccio; Riley, David R. Current Opinion in Microbiology, Vol. 23 https://doi.org/10.1016/j.mib.2014.11.016	journal	February 2015
A Novel Tool for Microbial Genome Editing Using the Restriction-Modification System Bai, Hua; Deng, Aihua; Liu, Shuwen ACS Synthetic Biology, Vol. 7, Issue 1 https://doi.org/10.1021/acssynbio.7b00254	journal	August 2017
Metagenomic insights into evolution of a heavy metal-contaminated groundwater microbial community Hemme, Christopher L.; Deng, Ye; Gentry, Terry J. The ISME Journal, Vol. 4, Issue 5 https://doi.org/10.1038/ismej.2009.154	journal	February 2010
Nanopore sequencing and assembly of a human genome with ultra-long reads Jain, Miten; Koren, Sergey; Miga, Karen H. Nature Biotechnology, Vol. 36, Issue 4 https://doi.org/10.1038/nbt.4060	journal	January 2018
Improved data analysis for the MinION nanopore sequencer Jain, Miten; Fiddes, Ian T.; Miga, Karen H. Nature Methods, Vol. 12, Issue 4 https://doi.org/10.1038/nmeth.3290	journal	February 2015
Detecting DNA cytosine methylation using nanopore sequencing Simpson, Jared T.; Workman, Rachael E.; Zuzarte, P. C. Nature Methods, Vol. 14, Issue 4 https://doi.org/10.1038/nmeth.4184	journal	February 2017
Template-based protein structure modeling using the RaptorX web server Källberg, Morten; Wang, Haipeng; Wang, Sheng Nature Protocols, Vol. 7, Issue 8 https://doi.org/10.1038/nprot.2012.085	journal	July 2012
Mobile genetic elements: the agents of open source evolution Frost, Laura S.; Leplae, Raphael; Summers, Anne O. Nature Reviews Microbiology, Vol. 3, Issue 9 https://doi.org/10.1038/nrmicro1235	journal	September 2005
Horizontal gene transfer: perspectives at a crossroads of scientific disciplines Smets, Barth F.; Barkay, Tamar Nature Reviews Microbiology, Vol. 3, Issue 9 https://doi.org/10.1038/nrmicro1253	journal	September 2005
The selective pressures on the microbial community in a metal-contaminated aquifer Carlson, Hans K.; Price, Morgan N.; Callaghan, Mark The ISME Journal, Vol. 13, Issue 4 https://doi.org/10.1038/s41396-018-0328-1	journal	December 2018
High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries Jain, Chirag; Rodriguez-R, Luis M.; Phillippy, Adam M. Nature Communications, Vol. 9, Issue 1 https://doi.org/10.1038/s41467-018-07641-9	journal	November 2018
Single-molecule sequencing detection of N6-methyladenine in microbial reference materials McIntyre, Alexa B. R.; Alexander, Noah; Grigorev, Kirill Nature Communications, Vol. 10, Issue 1 https://doi.org/10.1038/s41467-019-08289-9	journal	February 2019
Deciphering bacterial epigenomes using modern sequencing technologies Beaulaurier, John; Schadt, Eric E.; Fang, Gang Nature Reviews Genetics, Vol. 20, Issue 3 https://doi.org/10.1038/s41576-018-0081-3	journal	December 2018
Assembly of long, error-prone reads using repeat graphs Kolmogorov, Mikhail; Yuan, Jeffrey; Lin, Yu Nature Biotechnology, Vol. 37, Issue 5 https://doi.org/10.1038/s41587-019-0072-8	journal	April 2019
Pan-genome analysis of Bacillus for microbiome profiling Kim, Yihwan; Koh, InSong; Young Lim, Mi Scientific Reports, Vol. 7, Issue 1 https://doi.org/10.1038/s41598-017-11385-9	journal	September 2017
The complete methylome of an entomopathogenic bacterium reveals the existence of loci with unmethylated Adenines Payelleville, Amaury; Legrand, Ludovic; Ogier, Jean-Claude Scientific Reports, Vol. 8, Issue 1 https://doi.org/10.1038/s41598-018-30620-5	journal	August 2018
Genetic variation regulates the activation and specificity of Restriction-Modification systems in Neisseria gonorrhoeae Sánchez-Busó, Leonor; Golparian, Daniel; Parkhill, Julian Scientific Reports, Vol. 9, Issue 1 https://doi.org/10.1038/s41598-019-51102-2	journal	October 2019
BPGA- an ultra-fast pan-genome analysis pipeline Chaudhari, Narendrakumar M.; Gupta, Vinod Kumar; Dutta, Chitra Scientific Reports, Vol. 6, Issue 1 https://doi.org/10.1038/srep24373	journal	April 2016
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial "pan-genome" Tettelin, H.; Masignani, V.; Cieslewicz, M. J. Proceedings of the National Academy of Sciences, Vol. 102, Issue 39 https://doi.org/10.1073/pnas.0506758102	journal	September 2005
Minimap2: pairwise alignment for nucleotide sequences Li, Heng Bioinformatics, Vol. 34, Issue 18 https://doi.org/10.1093/bioinformatics/bty191	journal	May 2018
DeepSignal: detecting DNA methylation state from Nanopore sequencing reads using deep-learning Ni, Peng; Huang, Neng; Zhang, Zhi Bioinformatics, Vol. 35, Issue 22 https://doi.org/10.1093/bioinformatics/btz276	journal	April 2019
Whole genomic DNA sequencing and comparative genomic analysis of Arthrospira platensis : high genome plasticity and genetic diversity Xu, Teng; Qin, Song; Hu, Yongwu DNA Research, Vol. 23, Issue 4 https://doi.org/10.1093/dnares/dsw023	journal	June 2016
MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0 Tamura, Koichiro; Stecher, Glen; Peterson, Daniel Molecular Biology and Evolution, Vol. 30, Issue 12 https://doi.org/10.1093/molbev/mst197	journal	October 2013
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Thompson, Julie D.; Higgins, Desmond G.; Gibson, Toby J. Nucleic Acids Research, Vol. 22, Issue 22, p. 4673-4680 https://doi.org/10.1093/nar/22.22.4673	journal	January 1994
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes Roberts, R. J. Nucleic Acids Research, Vol. 31, Issue 7 https://doi.org/10.1093/nar/gkg274	journal	April 2003
REBASE—a database for DNA restriction and modification: enzymes, genes and genomes Roberts, Richard J.; Vincze, Tamas; Posfai, Janos Nucleic Acids Research, Vol. 38, Issue suppl_1 https://doi.org/10.1093/nar/gkp874	journal	October 2009
Evolutionary genome engineering using a restriction–modification system Asakura, Yoko; Kojima, Hiroyuki; Kobayashi, Ichizo Nucleic Acids Research, Vol. 39, Issue 20 https://doi.org/10.1093/nar/gkr585	journal	July 2011
BacMet: antibacterial biocide and metal resistance genes database Pal, Chandan; Bengtsson-Palme, Johan; Rensing, Christopher Nucleic Acids Research, Vol. 42, Issue D1 https://doi.org/10.1093/nar/gkt1252	journal	December 2013
Specificity of the ModA11, ModA12 and ModD1 epigenetic regulator N6-adenine DNA methyltransferases of Neisseria meningitidis Seib, Kate L.; Jen, Freda E. -C.; Tan, Aimee Nucleic Acids Research, Vol. 43, Issue 8 https://doi.org/10.1093/nar/gkv219	journal	April 2015
Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center Wattam, Alice R.; Davis, James J.; Assaf, Rida Nucleic Acids Research, Vol. 45, Issue D1 https://doi.org/10.1093/nar/gkw1017	journal	November 2016
Comparative genome and methylome analysis reveals restriction/modification system diversity in the gut commensal Bifidobacterium breve Bottacini, Francesca; Morrissey, Ruth; Roberts, Richard John Nucleic Acids Research, Vol. 46, Issue 4 https://doi.org/10.1093/nar/gkx1289	journal	December 2017
IslandViewer 4: expanded prediction of genomic islands for larger-scale datasets Bertelli, Claire; Laird, Matthew R.; Williams, Kelly P. Nucleic Acids Research, Vol. 45, Issue W1 https://doi.org/10.1093/nar/gkx343	journal	May 2017
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses Huerta-Cepas, Jaime; Szklarczyk, Damian; Heller, Davide Nucleic Acids Research, Vol. 47, Issue D1 https://doi.org/10.1093/nar/gky1085	journal	November 2018
Gene duplication as a mechanism of genomic adaptation to a changing environment Kondrashov, Fyodor A. Proceedings of the Royal Society B: Biological Sciences, Vol. 279, Issue 1749 https://doi.org/10.1098/rspb.2012.1108	journal	October 2012
The bacterial species definition in the genomic era Konstantinidis, Konstantinos T.; Ramette, Alban; Tiedje, James M. Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 361, Issue 1475 https://doi.org/10.1098/rstb.2006.1920	journal	October 2006
Rhodanobacter denitrificans sp. nov., isolated from nitrate-rich zones of a contaminated aquifer Prakash, Om; Green, Stefan J.; Jasrotia, Puja International Journal of Systematic and Evolutionary Microbiology, Vol. 62, Issue Pt_10 https://doi.org/10.1099/ijs.0.035840-0	journal	October 2012
Rhodanobacter humi sp. nov., an acid-tolerant and alkalitolerant gammaproteobacterium isolated from forest soil Dahal, Ram Hari; Kim, Jaisoo International Journal of Systematic and Evolutionary Microbiology, Vol. 67, Issue 5 https://doi.org/10.1099/ijsem.0.001786	journal	May 2017
Rhodanobacter rhizosphaerae sp. nov., isolated from soil of ginseng rhizosphere Cho, Geon-Yeong; Lee, Jae-Chan; Whang, Kyung-Sook International Journal of Systematic and Evolutionary Microbiology, Vol. 67, Issue 5 https://doi.org/10.1099/ijsem.0.001825	journal	May 2017
Mauve: Multiple Alignment of Conserved Genomic Sequence With Rearrangements Darling, A. C. E. Genome Research, Vol. 14, Issue 7 https://doi.org/10.1101/gr.2289704	journal	June 2004
Comparative genomics and the study of evolution by natural selection Ellegren, Hans Molecular Ecology, Vol. 17, Issue 21 https://doi.org/10.1111/j.1365-294X.2008.03954.x	journal	November 2008
Comparative Genomic Analysis Reveals the Distribution, Organization, and Evolution of Metal Resistance Genes in the Genus Acidithiobacillus Li, Liangzhi; Liu, Zhenghua; Meng, Delong Applied and Environmental Microbiology, Vol. 85, Issue 2 https://doi.org/10.1128/AEM.02153-18	journal	January 2019
Denitrifying Bacteria Isolated from Terrestrial Subsurface Sediments Exposed to Mixed-Waste Contamination Green, S. J.; Prakash, O.; Gihring, T. M. Applied and Environmental Microbiology, Vol. 76, Issue 10 https://doi.org/10.1128/AEM.03069-09	journal	March 2010
Type I Restriction Systems: Sophisticated Molecular Machines (a Legacy of Bertani and Weigle) Murray, N. E. Microbiology and Molecular Biology Reviews, Vol. 64, Issue 2 https://doi.org/10.1128/MMBR.64.2.412-434.2000	journal	June 2000
Lateral Gene Transfer in a Heavy Metal-Contaminated-Groundwater Microbial Community Hemme, Christopher L.; Green, Stefan J.; Rishishwar, Lavanya mBio, Vol. 7, Issue 2 https://doi.org/10.1128/mBio.02234-15	journal	April 2016
EDGAR: A software framework for the comparative analysis of prokaryotic genomes Blom, Jochen; Albaum, Stefan P.; Doppmeier, Daniel BMC Bioinformatics, Vol. 10, Issue 1 https://doi.org/10.1186/1471-2105-10-154	journal	May 2009
Understanding the evolutionary relationships and major traits of Bacillus through comparative genomics Alcaraz, Luis David; Moreno-Hagelsieb, Gabriel; Eguiarte, Luis E. BMC Genomics, Vol. 11, Issue 1 https://doi.org/10.1186/1471-2164-11-332	journal	May 2010
Comparative genomic analysis of four representative plant growth-promoting rhizobacteria in Pseudomonas Shen, Xuemei; Hu, Hongbo; Peng, Huasong BMC Genomics, Vol. 14, Issue 1 https://doi.org/10.1186/1471-2164-14-271	journal	January 2013
Comparative genomic analysis of Acinetobacter baumannii clinical isolates reveals extensive genomic variation and diverse antibiotic resistance determinants Liu, Fei; Zhu, Yuying; Yi, Yong BMC Genomics, Vol. 15, Issue 1 https://doi.org/10.1186/1471-2164-15-1163	journal	January 2014
The RAST Server: Rapid Annotations using Subsystems Technology Aziz, Ramy K.; Bartels, Daniela; Best, Aaron A. BMC Genomics, Vol. 9, Issue 1, Article No. 75 https://doi.org/10.1186/1471-2164-9-75	journal	January 2008
Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies Wang, Yu; Guo, Jinxin; Wang, Lin BMC Genomics, Vol. 20, Issue 1 https://doi.org/10.1186/s12864-019-5804-0	journal	June 2019
Comparative genomic analysis revealed great plasticity and environmental adaptation of the genomes of Enterococcus faecium Zhong, Zhi; Kwok, Lai-Yu; Hou, Qiangchuan BMC Genomics, Vol. 20, Issue 1 https://doi.org/10.1186/s12864-019-5975-8	journal	July 2019
Performance of neural network basecalling tools for Oxford Nanopore sequencing Wick, Ryan R.; Judd, Louise M.; Holt, Kathryn E. Genome Biology, Vol. 20, Issue 1 https://doi.org/10.1186/s13059-019-1727-y	journal	June 2019
Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads Wick, Ryan R.; Judd, Louise M.; Gorrie, Claire L. PLOS Computational Biology, Vol. 13, Issue 6 https://doi.org/10.1371/journal.pcbi.1005595	journal	June 2017
Discordance of Species Trees with Their Most Likely Gene Trees Degnan, James H.; Rosenberg, Noah A. PLoS Genetics, Vol. 2, Issue 5 https://doi.org/10.1371/journal.pgen.0020068	journal	May 2006
Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement Walker, Bruce J.; Abeel, Thomas; Shea, Terrance PLoS ONE, Vol. 9, Issue 11 https://doi.org/10.1371/journal.pone.0112963	journal	November 2014
Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia Johnston, Christopher D.; Skeete, Chelsey A.; Fomenkov, Alexey PLOS ONE, Vol. 12, Issue 9 https://doi.org/10.1371/journal.pone.0185234	journal	September 2017
In-silico Taxonomic Classification of 373 Genomes Reveals Species Misidentification and New Genospecies within the Genus Pseudomonas Tran, Phuong N.; Savka, Michael A.; Gan, Han Ming Frontiers in Microbiology, Vol. 8 https://doi.org/10.3389/fmicb.2017.01296	journal	July 2017
New Insights into the Diversity of the Genus Faecalibacterium Benevides, Leandro; Burman, Sriti; Martin, Rebeca Frontiers in Microbiology, Vol. 8 https://doi.org/10.3389/fmicb.2017.01790	journal	September 2017
Genome Sequencing and Pan-Genome Analysis of 23 Corallococcus spp. Strains Reveal Unexpected Diversity, With Particular Plasticity of Predatory Gene Sets Livingstone, Paul G.; Morphew, Russell M.; Whitworth, David E. Frontiers in Microbiology, Vol. 9 https://doi.org/10.3389/fmicb.2018.03187	journal	December 2018
Mechanism Across Scales: A Holistic Modeling Framework Integrating Laboratory and Field Studies for Microbial Ecology Lui, Lauren M.; Majumder, Erica L. -W.; Smith, Heidi J. Frontiers in Microbiology, Vol. 12 https://doi.org/10.3389/fmicb.2021.642422	journal	March 2021
The Patchy Distribution of Restriction–Modification System Genes and the Conservation of Orphan Methyltransferases in Halobacteria Fullmer, Matthew S.; Ouellette, Matthew; Louyakis, Artemis S. Genes, Vol. 10, Issue 3 https://doi.org/10.3390/genes10030233	journal	March 2019
Mobility of DNA sequence recognition domains in DNA methyltransferases suggests epigenetics-driven adaptive evolution Furuta, Yoshikazu; Kobayashi, Ichizo Mobile Genetic Elements, Vol. 2, Issue 6 https://doi.org/10.4161/mge.23371	journal	November 2012

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59 BASIC BIOLOGICAL SCIENCES
Rhodanobacter
comparative genomics
horizontal gene transfer
methylation
negative selection
restriction-modification system genes

Title: Genomic Features and Pervasive Negative Selection in Rhodanobacter Strains Isolated from Nitrate and Heavy Metal Contaminated Aquifer

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