Cobalamin-Dependent Radical S -Adenosylmethionine Enzymes: Capitalizing on Old Motifs for New Functions

Bridwell-Rabb, Jennifer; Li, Bin; Drennan, Catherine L.

doi:10.1021/acsbiomedchemau.1c00051

Title: Cobalamin-Dependent Radical S -Adenosylmethionine Enzymes: Capitalizing on Old Motifs for New Functions

Journal Article · 26 January 2022 · ACS Bio & Med Chem Au

DOI: https://doi.org/10.1021/acsbiomedchemau.1c00051 · OSTI ID:1842552

^[1]; Li, Bin ^[1];

^[2]

Department of Chemistry, University of Michigan, 930 N University Avenue, Ann Arbor, Michigan 48109, United States
Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States, Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States, Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

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Research Organization:: Univ. of Michigan, Ann Arbor, MI (United States); University of Michigan, Ann Arbor, MI (United States)

Sponsoring Organization:: National Institutes of Health; USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0021240

OSTI ID:: 1842552

Journal Information:: ACS Bio & Med Chem Au, Journal Name: ACS Bio & Med Chem Au Journal Issue: 3 Vol. 2; ISSN 2694-2437

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
S-adenosylmethionine
chemical structure
cluster chemistry
cobalamin
metalloenzyme
monomers
organic reactions
peptides and proteins
radical SAM
vitamin B12

Title: Cobalamin-Dependent Radical S -Adenosylmethionine Enzymes: Capitalizing on Old Motifs for New Functions

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