Editorial: Multi-Omics Technologies for Optimizing Synthetic Biomanufacturing

Journal Article · 14 December 2021 · Frontiers in Bioengineering and Biotechnology

DOI: https://doi.org/10.3389/fbioe.2021.818010 · OSTI ID:1841872

Kim, Young-Mo  ^[1]; Petzold, Christopher J. ^[2]; Kerkhoven, Eduard J. ^[3]; Baker, Scott E.  ^[4]

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1. Pacific Northwest National Lab. (PNNL), Richland, WA (United States); USDOE Agile BioFoundry, Emeryville, CA (United States)
2. USDOE Agile BioFoundry, Emeryville, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
3. Chalmers University of Technology, Gothenburg (Sweden)
4. USDOE Agile BioFoundry, Emeryville, CA (United States); Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

Industrial manufacturing endures as an essential human activity yielding a variety of useful products; it plays a significant role in the global economy with huge impacts in everyday life. However, the manufacturing process requires consumption of various raw materials (especially petroleum derivatives), generates a variety of harmful waste products, causes pollution, and is energetically inefficient. Biological manufacturing from sustainable, affordable, and scalable feedstocks potentially enables the displacement of the entire portfolio of currently available products produced by industrial processes, enabling the manufacturing of renewable and eco-friendly products (Clomburg et al., 2017). Thus, successful development of a robust biomanufacturing strategy and technology platform, based on the latest advances in synthetic biology and chemical catalysis, will decrease both the cost and production time compared with previous manufacturing processes. Development of biomanufacturing processes using a synthetic biology platform requires the multidisciplinary efforts of science and engineering fields including molecular biology, microbiology, genetic engineering, informatics, metabolic modeling and chemical or process engineering (El Karoui et al., 2019).

• Research Organization: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
• Sponsoring Organization: USDOE Office of Energy Efficiency and Renewable Energy (EERE), Transportation Office. Bioenergy Technologies Office
• Grant/Contract Number: AC05-76RL01830
• OSTI ID: 1841872
• Report Number(s): PNNL-SA-168498
• Journal Information: Frontiers in Bioengineering and Biotechnology, Journal Name: Frontiers in Bioengineering and Biotechnology Vol. 9; ISSN 2296-4185
• Publisher: Frontiers Research FoundationCopyright Statement
• Country of Publication: United States
• Language: English