Epidemiology, Clinical Features, and Outcomes of Coccidioidomycosis, Utah, 2006–2015
[2];
- Univ. of Utah, Salt Lake City, UT (United States). School of Medicine
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- Centers for Disease Control and Prevention, Atlanta, GA (United States)
- Utah Department of Health, Salt Lake City, UT (United States)
- Intermountain Healthcare, Salt Lake City, UT (United States); Stanford Univ., Palo Alto, CA (United States). School of Medicine
On the basis of a 1957 geographic Coccidioides seropositivity survey, 3 counties in southwestern Utah, USA, were considered coccidioidomycosis-endemic, but there has been a paucity of information on the disease burden in Utah since. We report findings from a recent clinical and epidemiologic study of coccidioidomycosis in Utah. To describe clinical characteristics, we identified all coccidioidomycosis cases in an integrated health system in the state during 2006–2015. For epidemiologic analysis, we used cases reported to the Utah Department of Health during 2009–2015. Mean state incidence was 1.83 cases/100,000 population/year. Washington County, in southwestern Utah, had the highest incidence, 17.2 cases/100,000 population/year. In a generalized linear model with time as a fixed effect, mean annual temperature, population, and new construction were associated with regional variations in incidence. Using these variables in a spatiotemporal model, we estimated the adjusted regional variation by county to predict areas where Coccidioides infections might increase.
- Research Organization:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Organization:
- Intermountain Research and Medical Foundation; USDOE Laboratory Directed Research and Development (LDRD) Program; USDOE National Nuclear Security Administration (NNSA)
- Grant/Contract Number:
- 89233218CNA000001
- OSTI ID:
- 1825435
- Report Number(s):
- LA-UR--20-21991
- Journal Information:
- Emerging Infectious Diseases, Journal Name: Emerging Infectious Diseases Journal Issue: 9 Vol. 27; ISSN 1080-6040
- Publisher:
- Centers for Disease Control and PreventionCopyright Statement
- Country of Publication:
- United States
- Language:
- English
Similar Records
Coccidioidomycosis Dynamics in Relation to Climate in the Southwestern United States: Cocci. and climate in the SW U.S.
Estimating coccidioidomycosis endemicity while accounting for imperfect detection using spatio - temporal occupancy modeling