Recent developments in filtration media and respirator technology in response to COVID-19

Wang, Peter L.; Roschli, Alex; Paranthaman, M. Parans; Theodore, Merlin; Cramer, Corson L.; Zangmeister, Chris; Zhang, Yuepeng; Urban, Jeffrey J.; Love, Lonnie

doi:10.1557/s43577-021-00173-6

Title: Recent developments in filtration media and respirator technology in response to COVID-19

Journal Article · 14 September 2021 · MRS Bulletin

DOI: https://doi.org/10.1557/s43577-021-00173-6 · OSTI ID:1820484

; Roschli, Alex;

; Theodore, Merlin; Cramer, Corson L.; Zangmeister, Chris; Zhang, Yuepeng; Urban, Jeffrey J.; Love, Lonnie

Abstract The COVID-19 pandemic triggered a surge in demand for N95 or equivalent respirators that the global supply chain was unable to satisfy. This shortage in critical equipment has inspired research that addresses the immediate problems and has accelerated the development of the next-generation filtration media and respirators. This article provides a brief review of the most recent work with regard to face respirators and filtration media. We discuss filtration efficiency of the widely utilized cloth masks. Next, the sterilization of and reuse of existing N95 respirators to extend the existing stockpile is discussed. To expand near-term supplies, optimization of current manufacturing methods, such as melt-blown processes and electrospinning, has been explored. Future manufacturing methods have been investigated to address long-term supply shortages. Novel materials with antiviral and sterilizable properties with the ability for multiple reuses have been developed and will contribute to the development of the next generation of longer lasting multi-use N95 respirators. Finally, additively manufactured respirators are reviewed, which enable a rapidly deployable source of reusable respirators that can use any filtration fabric. Graphic abstract

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE Office of Energy Efficiency and Renewable Energy (EERE), Energy Efficiency Office. Advanced Manufacturing Office; USDOE Office of Science (SC), Basic Energy Sciences (BES); USDOE Office of Science (SC), Basic Energy Sciences (BES). Scientific User Facilities Division

Grant/Contract Number:: AC02-05CH11231; AC02-06CH11357; AC05-00OR22725

OSTI ID:: 1820484

Journal Information:: MRS Bulletin, Journal Name: MRS Bulletin Journal Issue: 9 Vol. 46; ISSN 0883-7694

Publisher:: Cambridge University Press (CUP)Copyright Statement

Country of Publication:: United States

Language:: English

References (52)

Spider‐Web‐Inspired PM _0.3 Filters Based on Self‐Sustained Electrostatic Nanostructured Networks Zhang, Shichao; Liu, Hui; Tang, Ning Advanced Materials, Vol. 32, Issue 29 https://doi.org/10.1002/adma.202002361	journal	June 2020
Encapsulating drugs in biodegradable ultrafine fibers through co-axial electrospinning Huang, Zheng-Ming; He, Chuang-Long; Yang, Aizhao Journal of Biomedical Materials Research Part A, Vol. 77A, Issue 1 https://doi.org/10.1002/jbm.a.30564	journal	January 2006
Microstructural Characterization, Mechanical, Physical and Thermal Properties of a Diesel Particulate Filter Calis Acikbas, Nurcan; Ture, Yigit; Gurlek, Emre Arabian Journal for Science and Engineering, Vol. 43, Issue 3 https://doi.org/10.1007/s13369-017-2872-9	journal	November 2017
Progress and Perspective of Antiviral Protective Material Zhou, Jialiang; Hu, Zexu; Zabihi, Fatemeh Advanced Fiber Materials, Vol. 2, Issue 3 https://doi.org/10.1007/s42765-020-00047-7	journal	June 2020
Electrospun Nanofibers-Based Face Masks Tebyetekerwa, Mike; Xu, Zhen; Yang, Shengyuan Advanced Fiber Materials, Vol. 2, Issue 3 https://doi.org/10.1007/s42765-020-00049-5	journal	June 2020
Experimental characterization of electrospinning: the electrically forced jet and instabilities Shin, Y. M.; Hohman, M. M.; Brenner, M. P. Polymer, Vol. 42, Issue 25 https://doi.org/10.1016/S0032-3861(01)00540-7	journal	December 2001
Quantitative Fit Tested N95 Respirator-Alternatives Generated With CT Imaging and 3D Printing: A Response to Potential Shortages During the COVID-19 Pandemic Ballard, David H.; Jammalamadaka, Udayabhanu; Meacham, Kathleen W. Academic Radiology, Vol. 28, Issue 2 https://doi.org/10.1016/j.acra.2020.11.005	journal	February 2021
N95 reprocessing by low temperature sterilization with 59% vaporized hydrogen peroxide during the 2020 COVID-19 pandemic Jatta, Maimuna; Kiefer, Carolyn; Patolia, Harsh American Journal of Infection Control, Vol. 49, Issue 1 https://doi.org/10.1016/j.ajic.2020.06.194	journal	January 2021
Probability of fit failure with reuse of N95 mask respirators Maranhao, Bruno; Scott, Alex W.; Scott, Alex R. British Journal of Anaesthesia, Vol. 125, Issue 3 https://doi.org/10.1016/j.bja.2020.06.023	journal	September 2020
Coating of ZnO nanoparticles onto the inner pore channel surface of SiC foam to fabricate a novel antibacterial air filter material Hu, Jian; Zhong, Zhaoxiang; Zhang, Feng Ceramics International, Vol. 41, Issue 5 https://doi.org/10.1016/j.ceramint.2015.02.016	journal	June 2015
Copper-impregnated three-layer mask efficiently inactivates SARS-CoV2 Hewawaduge, Chamith; Senevirathne, Amal; Jawalagatti, Vijayakumar Environmental Research, Vol. 196 https://doi.org/10.1016/j.envres.2021.110947	journal	May 2021
Evaluation of decontamination methods for commercial and alternative respirator and mask materials – view from filtration aspect Ou, Qisheng; Pei, Chenxing; Chan Kim, Seong Journal of Aerosol Science, Vol. 150 https://doi.org/10.1016/j.jaerosci.2020.105609	journal	December 2020
Highly permeable macroporous cordierite ceramics with controlled microstructure produced by particle-stabilized emulsions with a reactive thermal treatment Ma, Yu; Li, Jinhong; Wang, Xiang Journal of the European Ceramic Society, Vol. 37, Issue 9 https://doi.org/10.1016/j.jeurceramsoc.2017.03.035	journal	August 2017
N95 mask reuse in a major urban hospital: COVID-19 response process and procedure Czubryt, M. P.; Stecy, T.; Popke, E. Journal of Hospital Infection, Vol. 106, Issue 2 https://doi.org/10.1016/j.jhin.2020.07.035	journal	October 2020
Heat sterilization dramatically reduces filter efficiency of the majority of FFP2 and KN95 respirators van der Vossen, J. M. B. M.; Heerikhuisen, M.; Traversari, R. A. A. L. Journal of Hospital Infection, Vol. 107 https://doi.org/10.1016/j.jhin.2020.10.012	journal	January 2021
Recycling of poly(ethylene terephthalate) by electrospinning to enhanced the filtration efficiency Opálková Šišková, Alena; Frajová, Jaroslava; Nosko, Martin Materials Letters, Vol. 278 https://doi.org/10.1016/j.matlet.2020.128426	journal	November 2020
Sterilization of polypropylene membranes of facepiece respirators by ionizing radiation Pirker, Luka; Krajnc, Anja Pogačnik; Malec, Jan Journal of Membrane Science, Vol. 619 https://doi.org/10.1016/j.memsci.2020.118756	journal	February 2021
Electrospun ultrafine fibers for advanced face masks Zhang, Zhenfang; Ji, Dongxiao; He, Haijun Materials Science and Engineering: R: Reports, Vol. 143 https://doi.org/10.1016/j.mser.2020.100594	journal	January 2021
Manufacturing a low-cost ceramic water filter and filter system for the elimination of common pathogenic bacteria Simonis, J. J.; Basson, A. K. Physics and Chemistry of the Earth, Parts A/B/C, Vol. 50-52 https://doi.org/10.1016/j.pce.2012.05.001	journal	January 2012
Biodegradable CA/CPB electrospun nanofibers for efficient retention of airborne nanoparticles de Almeida, Daniela Sanches; Martins, Leila Droprinchinski; Muniz, Edvani Curti Process Safety and Environmental Protection, Vol. 144 https://doi.org/10.1016/j.psep.2020.07.024	journal	December 2020
Charged PVDF multilayer nanofiber filter in filtering simulated airborne novel coronavirus (COVID-19) using ambient nano-aerosols Leung, Wallace Woon-Fong; Sun, Qiangqiang Separation and Purification Technology, Vol. 245 https://doi.org/10.1016/j.seppur.2020.116887	journal	August 2020
Contributing factors to personal protective equipment shortages during the COVID-19 pandemic Cohen, Jennifer; Rodgers, Yana van der Meulen Preventive Medicine, Vol. 141 https://doi.org/10.1016/j.ypmed.2020.106263	journal	December 2020
Ceramic foams by powder processing Montanaro, L.; Jorand, Y.; Fantozzi, G. Journal of the European Ceramic Society, Vol. 18, Issue 9 https://doi.org/10.1016/s0955-2219(98)00063-6	journal	January 1998
Immediate-use steam sterilization sterilizes N95 masks without mask damage Carrillo, Irene O.; Floyd, Anna C. E.; Valverde, Christian M. Infection Control & Hospital Epidemiology, Vol. 41, Issue 9 https://doi.org/10.1017/ice.2020.145	journal	April 2020
Extended use or reuse of N95 respirators during COVID-19 pandemic: An overview of national regulatory authority recommendations Kobayashi, Leticia Mitiko; Marins, Bianca Ramos; Costa, Patrícia Cristina dos Santos Infection Control & Hospital Epidemiology, Vol. 41, Issue 11 https://doi.org/10.1017/ice.2020.173	journal	April 2020
Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong Cheng, Vincent C. C.; Wong, Shuk-Ching; Chen, Jonathan H. K. Infection Control & Hospital Epidemiology, Vol. 41, Issue 5 https://doi.org/10.1017/ice.2020.58	journal	March 2020
The role of masks and respirator protection against SARS-CoV-2 Wang, Qiang; Yu, Chaoran Infection Control & Hospital Epidemiology, Vol. 41, Issue 6 https://doi.org/10.1017/ice.2020.83	journal	March 2020
Rationale and process for N95 respirator sanitation and re-use in the COVID-19 pandemic Golladay, Gregory J.; Leslie, Kevin A.; Zuelzer, Wilhelm A. Infection Control & Hospital Epidemiology https://doi.org/10.1017/ice.2021.37	journal	February 2021
Hydrogen peroxide vapor decontamination of N95 respirators for reuse Kenney, Patrick A.; Chan, Benjamin K.; Kortright, Kaitlyn E. Infection Control & Hospital Epidemiology https://doi.org/10.1017/ice.2021.48	journal	February 2021
Photoactive Antiviral Face Mask with Self-Sterilization and Reusability Kumar, Sumit; Karmacharya, Mamata; Joshi, Shalik Ram Nano Letters, Vol. 21, Issue 1 https://doi.org/10.1021/acs.nanolett.0c03725	journal	November 2020
Daylight-Induced Antibacterial and Antiviral Nanofibrous Membranes Containing Vitamin K Derivatives for Personal Protective Equipment Zhang, Zheng; El-Moghazy, Ahmed Y.; Wisuthiphaet, Nicharee ACS Applied Materials & Interfaces, Vol. 12, Issue 44 https://doi.org/10.1021/acsami.0c14883	journal	October 2020
Daylight-Induced Antibacterial and Antiviral Cotton Cloth for Offensive Personal Protection Tang, Peixin; Zhang, Zheng; El-Moghazy, Ahmed Y. ACS Applied Materials & Interfaces, Vol. 12, Issue 44 https://doi.org/10.1021/acsami.0c15540	journal	October 2020
Hydration of Hydrophilic Cloth Face Masks Enhances the Filtration of Nanoparticles Zangmeister, Christopher D.; Radney, James G.; Staymates, Matthew E. ACS Applied Nano Materials, Vol. 4, Issue 3 https://doi.org/10.1021/acsanm.0c03319	journal	March 2021
Polymer, Additives, and Processing Effects on N95 Filter Performance Larsen, Gregory S.; Cheng, Yongqiang; Daemen, Luke L. ACS Applied Polymer Materials, Vol. 3, Issue 2 https://doi.org/10.1021/acsapm.0c01294	journal	January 2021
Can N95 Respirators Be Reused after Disinfection? How Many Times? Liao, Lei; Xiao, Wang; Zhao, Mervin ACS Nano, Vol. 14, Issue 5 https://doi.org/10.1021/acsnano.0c03597	journal	May 2020
Evaluation of Regeneration Processes for Filtering Facepiece Respirators in Terms of the Bacteria Inactivation Efficiency and Influences on Filtration Performance He, Weidong; Guo, Yinghe; Gao, Hanchao ACS Nano, Vol. 14, Issue 10 https://doi.org/10.1021/acsnano.0c04782	journal	September 2020
Filtration Efficiencies of Nanoscale Aerosol by Cloth Mask Materials Used to Slow the Spread of SARS-CoV-2 Zangmeister, Christopher D.; Radney, James G.; Vicenzi, Edward P. ACS Nano, Vol. 14, Issue 7 https://doi.org/10.1021/acsnano.0c05025	journal	June 2020
Decontamination of SARS-CoV-2 and Other RNA Viruses from N95 Level Meltblown Polypropylene Fabric Using Heat under Different Humidities Campos, Rafael K.; Jin, Jing; Rafael, Grace H. ACS Nano, Vol. 14, Issue 10 https://doi.org/10.1021/acsnano.0c06565	journal	September 2020
Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE Cramer, Avilash K.; Plana, Deborah; Yang, Helen Scientific Reports, Vol. 11, Issue 1 https://doi.org/10.1038/s41598-021-81365-7	journal	January 2021
A comprehensive review on antimicrobial face masks: an emerging weapon in fighting pandemics Pullangott, Gayathri; Kannan, Uthradevi; S., Gayathri RSC Advances, Vol. 11, Issue 12 https://doi.org/10.1039/D0RA10009A	journal	January 2021
Meltblown technology for production of polymeric microfibers/nanofibers: A review Drabek, Jiri; Zatloukal, Martin Physics of Fluids, Vol. 31, Issue 9 https://doi.org/10.1063/1.5116336	journal	September 2019
Ceramic media amended with metal oxide for the capture of viruses in drinking water Brown, J.; Sobsey, M. D. Environmental Technology, Vol. 30, Issue 4 https://doi.org/10.1080/09593330902753461	journal	April 2009
UV light dosage distribution over irregular respirator surfaces. Methods and implications for safety Baluja, Aurora; Arines, Justo; Vilanova, Ramón Journal of Occupational and Environmental Hygiene, Vol. 17, Issue 9 https://doi.org/10.1080/15459624.2020.1786576	journal	August 2020
Ceramic Diesel Particulate Filters Adler, Joerg International Journal of Applied Ceramic Technology, Vol. 2, Issue 6 https://doi.org/10.1111/j.1744-7402.2005.02044.x	journal	November 2005
Decontamination of N95 masks for re-use employing 7 widely available sterilization methods Kumar, Anand; Kasloff, Samantha B.; Leung, Anders PLOS ONE, Vol. 15, Issue 12 https://doi.org/10.1371/journal.pone.0243965	journal	December 2020
Polymers with antiviral properties: A brief review [Polimery o własnościach antywirusowych] Zmonarski, Sławomir Zmonarski; Stojanowski, Jakub; Zmonarska, Joanna Polymers in Medicine, Vol. 50, Issue 2 https://doi.org/10.17219/pim/131643	journal	January 2020
Robocasting Periodic Lattices for Advanced Filtration Stuecker, John N.; Joseph, Cesarano III,; Smay, James E. The University of Texas at Austin https://doi.org/10.26153/tsw/3351	other	January 2001
Effectiveness of N95 Respirator Decontamination and Reuse against SARS-CoV-2 Virus Fischer, Robert J.; Morris, Dylan H.; van Doremalen, Neeltje Emerging Infectious Diseases, Vol. 26, Issue 9 https://doi.org/10.3201/eid2609.201524	journal	September 2020
Quadrupling the N95 Supply during the COVID-19 Crisis with an Innovative 3D-Printed Mask Adaptor Imbrie-Moore, Annabel M.; Park, Matthew H.; Zhu, Yuanjia Healthcare, Vol. 8, Issue 3 https://doi.org/10.3390/healthcare8030225	journal	July 2020
3-D Printed Protective Equipment during COVID-19 Pandemic Wesemann, Christian; Pieralli, Stefano; Fretwurst, Tobias Materials, Vol. 13, Issue 8 https://doi.org/10.3390/ma13081997	journal	April 2020
Face Masks and Respirators in the Fight Against the COVID-19 Pandemic: A Review of Current Materials, Advances and Future Perspectives O’Dowd, Kris; Nair, Keerthi M.; Forouzandeh, Parnia Materials, Vol. 13, Issue 15 https://doi.org/10.3390/ma13153363	journal	July 2020
Novel Three-Dimensional Ceramic Lattices as Catalyst Supports and Diesel Particulate Traps Stuecker, J. N.; Cesarano, J.; Miller, J. E. SAE 2003 World Congress & Exhibition, SAE Technical Paper Series https://doi.org/10.4271/2003-01-0838	conference	March 2003

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Title: Recent developments in filtration media and respirator technology in response to COVID-19

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