Tuning the near infrared II emitting wavelength of small molecule dyes by single atom alteration

Qian, Kun; Qu, Chunrong; Ma, Xiangyu; Chen, Hao; Kandawa-Schulz, Martha; Song, Wei; Miao, Weimin; Wang, Yihong; Cheng, Zhen

doi:10.1039/c9cc08434g

Title: Tuning the near infrared II emitting wavelength of small molecule dyes by single atom alteration

Journal Article · 29 November 2019 · ChemComm

DOI: https://doi.org/10.1039/c9cc08434g · OSTI ID:1801820

Qian, Kun ^[1]; Qu, Chunrong ^[2]; Ma, Xiangyu ^[3]; Chen, Hao ^[2]; Kandawa-Schulz, Martha ^[4]; Song, Wei ^[4]; Miao, Weimin ^[5];

^[3];

^[2]

Southeast Univ., Nanjing (China). School of Chemistry and Chemical Engineering; Stanford Univ., CA (United States). Molecular Imaging Program at Stanford (MIPS). Bio-X Program. Dept. of Radiology. Canary Center at Stanford for Cancer Early Detection; OSTI
Stanford Univ., CA (United States). Molecular Imaging Program at Stanford (MIPS). Bio-X Program. Dept. of Radiology. Canary Center at Stanford for Cancer Early Detection
Southeast Univ., Nanjing (China). School of Chemistry and Chemical Engineering
Univ. of Namibia, Windhoek (Namibia). Dept. of Chemistry and Biochemistry
Jiangsu Meizhong Medical Technology Co., Ltd, Nantong (China)

A series of small molecule dyes demonstrate the feasibility of manipulating Near Infrared II emission by simply altering the donors’ heteroatoms, which involved both electronegativity and intramolecular steric effects. Furthermore, these dyes show high resolution and stability for in vivo imaging after being complexed with human serum albumin.

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Research Organization:: Stanford Univ., CA (United States)

Sponsoring Organization:: USDOE; USDOE Office of Science (SC), Biological and Environmental Research (BER)

Grant/Contract Number:: SC0008397

OSTI ID:: 1801820

Journal Information:: ChemComm, Journal Name: ChemComm Journal Issue: 4 Vol. 56; ISSN 1359-7345

Publisher:: Royal Society of ChemistryCopyright Statement

Country of Publication:: United States

Language:: English

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