Poly(vinyl alcohol) Hydrogels with Broad-Range Tunable Mechanical Properties via the Hofmeister Effect
Abstract
Hydrogels, exhibiting wide applications in soft robotics, tissue engineering, implantable electronics, etc., often require sophisticately tailoring of the hydrogel mechanical properties to meet specific demands. For examples, soft robotics necessitates tough hydrogels; stem cell culturing demands various tissue-matching modulus; and neuron probes desire dynamically tunable modulus. Herein, a strategy to broadly alter the mechanical properties of hydrogels reversibly via tuning the aggregation states of the polymer chains by ions based on the Hofmeister effect is reported. An ultratough poly(vinyl alcohol) (PVA) hydrogel as an exemplary material (toughness 150 ± 20 MJ m-3), which surpasses synthetic polymers like poly(dimethylsiloxane), synthetic rubber, and natural spider silk is fabricated. With various ions, the hydrogel's various mechanical properties are continuously and reversibly in situ modulated over a large window: tensile strength from 50 ± 9 kPa to 15 ± 1 MPa, toughness from 0.0167 ± 0.003 to 150 ± 20 MJ m-3, elongation from 300 ± 100% to 2100 ± 300%, and modulus from 24 ± 2 to 2500 ± 140 kPa. Importantly, the ions serve as gelation triggers and property modulators only, not necessarily required to remain in the gel, maintaining the high biocompatibility of PVA without excess ions. Overall, this strategy, enablingmore »
- Authors:
-
[1];
[2]
- Univ. of California, Los Angeles, CA (United States); Shanghai Jiao Tong Univ. (China). State Key Lab. of Metal Matrix Composites
- Univ. of California, Los Angeles, CA (United States)
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Shanghai Jiao Tong Univ. (China). State Key Lab. of Metal Matrix Composites
- Publication Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- National Science Foundation (NSF); US Air Force Office of Scientific Research (AFOSR); US Office of Naval Research (ONR); USDOE Office of Science (SC)
- OSTI Identifier:
- 1774628
- Grant/Contract Number:
- AC02-06CH11357; 1724526; FA9550-17-1-0311; FA9550-18-1-0449; FA9550-20-1-0344; N000141712117; N00014-18-1-2314
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Advanced Materials
- Additional Journal Information:
- Journal Volume: 33; Journal Issue: 11; Journal ID: ISSN 0935-9648
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 36 MATERIALS SCIENCE; Hofmeister effect; ions; poly (vinyl alcohol); tough hydrogel; tunable mechanical properties
Citation Formats
Wu, Shuwang, Hua, Mutian, Alsaid, Yousif, Du, Yingjie, Ma, Yanfei, Zhao, Yusen, Lo, Chiao‐Yueh, Wang, Canran, Wu, Dong, Yao, Bowen, Strzalka, Joseph, Zhou, Hua, Zhu, Xinyuan, and He, Ximin. Poly(vinyl alcohol) Hydrogels with Broad-Range Tunable Mechanical Properties via the Hofmeister Effect. United States: N. p., 2021.
Web. doi:10.1002/adma.202007829.
Wu, Shuwang, Hua, Mutian, Alsaid, Yousif, Du, Yingjie, Ma, Yanfei, Zhao, Yusen, Lo, Chiao‐Yueh, Wang, Canran, Wu, Dong, Yao, Bowen, Strzalka, Joseph, Zhou, Hua, Zhu, Xinyuan, & He, Ximin. Poly(vinyl alcohol) Hydrogels with Broad-Range Tunable Mechanical Properties via the Hofmeister Effect. United States. https://doi.org/10.1002/adma.202007829
Wu, Shuwang, Hua, Mutian, Alsaid, Yousif, Du, Yingjie, Ma, Yanfei, Zhao, Yusen, Lo, Chiao‐Yueh, Wang, Canran, Wu, Dong, Yao, Bowen, Strzalka, Joseph, Zhou, Hua, Zhu, Xinyuan, and He, Ximin. Mon .
"Poly(vinyl alcohol) Hydrogels with Broad-Range Tunable Mechanical Properties via the Hofmeister Effect". United States. https://doi.org/10.1002/adma.202007829. https://www.osti.gov/servlets/purl/1774628.
@article{osti_1774628,
title = {Poly(vinyl alcohol) Hydrogels with Broad-Range Tunable Mechanical Properties via the Hofmeister Effect},
author = {Wu, Shuwang and Hua, Mutian and Alsaid, Yousif and Du, Yingjie and Ma, Yanfei and Zhao, Yusen and Lo, Chiao‐Yueh and Wang, Canran and Wu, Dong and Yao, Bowen and Strzalka, Joseph and Zhou, Hua and Zhu, Xinyuan and He, Ximin},
abstractNote = {Hydrogels, exhibiting wide applications in soft robotics, tissue engineering, implantable electronics, etc., often require sophisticately tailoring of the hydrogel mechanical properties to meet specific demands. For examples, soft robotics necessitates tough hydrogels; stem cell culturing demands various tissue-matching modulus; and neuron probes desire dynamically tunable modulus. Herein, a strategy to broadly alter the mechanical properties of hydrogels reversibly via tuning the aggregation states of the polymer chains by ions based on the Hofmeister effect is reported. An ultratough poly(vinyl alcohol) (PVA) hydrogel as an exemplary material (toughness 150 ± 20 MJ m-3), which surpasses synthetic polymers like poly(dimethylsiloxane), synthetic rubber, and natural spider silk is fabricated. With various ions, the hydrogel's various mechanical properties are continuously and reversibly in situ modulated over a large window: tensile strength from 50 ± 9 kPa to 15 ± 1 MPa, toughness from 0.0167 ± 0.003 to 150 ± 20 MJ m-3, elongation from 300 ± 100% to 2100 ± 300%, and modulus from 24 ± 2 to 2500 ± 140 kPa. Importantly, the ions serve as gelation triggers and property modulators only, not necessarily required to remain in the gel, maintaining the high biocompatibility of PVA without excess ions. Overall, this strategy, enabling high mechanical performance and broad dynamic tunability, presents a universal platform for broad applications from biomedicine to wearable electronics.},
doi = {10.1002/adma.202007829},
journal = {Advanced Materials},
number = 11,
volume = 33,
place = {United States},
year = {Mon Feb 08 00:00:00 EST 2021},
month = {Mon Feb 08 00:00:00 EST 2021}
}
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