Title: Two clusters of residues contribute to the activity and substrate specificity of Fm1, a bifunctional oleate and linoleate desaturase of fungal origin

Journal Article · · Journal of Biological Chemistry
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Not Available

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES); USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22). Chemical Sciences, Geosciences & Biosciences Division
Grant/Contract Number:
SC0012704
OSTI ID:
1769474
Report Number(s):
BNL-209319-2018-JAAM; S0021925820311108; PII: S0021925820311108
Journal Information:
Journal of Biological Chemistry, Journal Name: Journal of Biological Chemistry Journal Issue: 51 Vol. 293; ISSN 0021-9258
Publisher:
ElsevierCopyright Statement
Country of Publication:
United States
Language:
English

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37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES
bifunctional desaturase
lipid metabolism
phospholipid
polyunsaturated fatty acid
regioselectivity
structural determinants
substrate specificity